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a new Pristiq guinea pig here..... Rate Topic: ****- 2 Votes

#41 Guest_guest julie_*

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Posted 20 August 2008 - 02:20 PM

Blue eyes and Isolde

Thank you for posting your experiences. Today my doc put me on Pristiq and I have been quite anxious about what to expect. I appreciate you taking the time to document what has happened to you.


Julie

#42 User is offline   Isolde 

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Posted 20 August 2008 - 02:45 PM

Just make sure that you stick with it. It doesn't jolt you like some anti-depressants do and it does take awhile before you notice changes. At least it did with me.
:D
Bipolar since my twenties.
Hypothyroid since my thirties.

Currently taking Seroquel,200 per night.
Klonopin 0.10 at night.
Ritalin SR 20 mg am.
Synthroid 137 mcg a day.
Pristiq 40 mg am (new)

I've had back surgery in my twenties; a hip replacement 4 years ago, a c-section at 36,
I am currently extremely exhausted/foggy thinking, depressed.
I am feeling much better, alive and active and able to do activities of daily living.

#43 Guest_Guest_kimbo_*_*

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Posted 24 August 2008 - 10:48 AM

I agree, keep with it. I am beginning week four and feel FABULOUS! I have tried Paxil, Zoloft, Prozac, Celexa, Lexapro, Wellbutrin and back to Prozac last. I can not even tell you how much better I feel on Pristiq. I have had some adverse reactions like the first week I was very irritable-that went away, I have not had the stomach upset that others have expressed (wish I could report that I have lost some weight, I have not BUT I have not gained any either which I did with others), it takes a bit longer to 'compete' sexual experiences but it is still there and enjoyable, and I have not had insomnia since the first week. In fact I sleep more soundly at night and wake more energized in the morning.
The best way that I can decribe this experience is that I feel like I lived in smog, walked in sand and carried water buckets on other AD's and now I see much more clearly, my senses are not dull, I have a spring in my step and I am much more confident and relaxed...I can enjoy my life, my children, my husband, my friends, my pets and my experiences. I was so reluctant to try all of these meds, I hope this post helps some one else who may be on the fence.
Remember that not everyone reacts the same though, if it doesn't work for you try another one. I am so glad I took the plunge. FYI-while on Lexapro the first year it worked great, just stopped. Prozac was what I was on the longest and return to after the Lexapro stopped helping, other than weight gain and sluggish feeling, no energy, no motivation- it did help my mood.
I hope I never have to stop taking the Pristiq, and I don't have the poop out with it, it has changed my life!
kimbo

#44 Guest_Sorcy_*

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  Posted 08 September 2008 - 01:41 PM

View PostBlueEyes, on Jul 22 2008, 07:09 AM, said:

View Poststrachml, on Jul 21 2008, 10:13 PM, said:

Hi everyone! :P

I was diagnosed with Generalized Anxiety Disorder and Panic Disorder in January 2002. I was on paxil (paroxetene) for about 5 1/2 years, which obviously worked pretty well, but I thought maybe trying a different drug would aleiviate some of the minor side effects I had (weight gain, pretty much no sex drive, etc). I tried lexapro for 2 months (not enough time to notice any change), then was switched to Effexor XR to also help treat a chronic pain problem. In addition to the GAD and PD, I have a fear of flying that I use ativan for.

I was fine on Effexor XR-- it didn't noticably help the pain problem, but anxiety was fairly non-existant. The high dose I worked up to (300mg) was great for when I flew (with the addition of the ativan I took a couple hours before the flight, it pretty much knocked me out, which is the best thing to happen when I fly haha!). I went back down to 225mg due to a little moodiness, and was still fine. UNFORTUNATELY, around the time I started Effexor (this past Jan) I also started having horrible acne breakouts (I've struggled with mild-persistent acne for 11 years, but this was much noticably worse :wtf: ). I blamed it on new birth control at first, but having been off that for about 3 months and still having the horrible acne... I realized that the Effexor may be the culprit (doing Yahoo searches, I saw that I may not have been the only one! But it seems like a pretty rare side effect). The acne was/is causing me problems, so I went back to the doc again...

My doc suggested Pristiq, saying it was the same compounds as Effexor, but seems to nix the side effects (seems too good to be true to me??)-- I was wary, but said I'd try it. I've taken it for 3 nights now, and I'm notiably more anxious. I hadn't felt the unexplained "everyday anxiety" (explained: e.g. forgetting to take my pills at night, or having to fly, etc.) for a long time. So this is definitely not a good sign to me. Sure, maybe it'll help the acne problem and not cause weight gain, which is great!!! But ultimately, I'm trying to not have anxiety/panic attacks here!!!!

I didn't have any problems when I started Effexor XR--- didn't feel like I needed time to ease into it. It seemed to start working right off the bat. My doc told me I didn't need to wean off Effexor to start Pristiq-- I could just go straight into 50mg from the 225 Effexor. I'm thinking of calling my doc tomorrow and telling him that its not going well so far.

I understand that it sometimes takes a while to really work, but dealing with the anxiety is really posing a challenge for me since I've pretty much been without it for a while.

I was seriously considering going back on Paxil... I didn't gain an exorbitant amount of weight, and I can deal with decreased/non-existant sex drive, even though it sucks. Or even lexapro since I didn't get a good feel for that one. Effexor did the same thing paxil did for me in terms of anxiety, but I'd rather deal with some weight gain than worsened acne (mind you, I still have the mild acne anyway!). BLAH!!!! :violin:

Any suggestion????? I would appreciate any ideas :)


I would give it a little more time unless it is completely unbearable. I'm no expert, but most of the side effects I experienced would last for a few days to a week, then they would be gone. Of course, everyone is affected differently. I had a couple of days of major anxiety as well, but that subsided. My pdoc gave me xanax to take as needed should any anxiety occur again, but it hasn't. I think it's worth sticking with it for a couple of weeks if you can. It might be worth it if it means you can avoid jumping back on the med-go-round. There are a couple of Pristiq threads for you to check out. I think there are a couple of people that take it for anxiety, you could always PM them and see how they are doing on it.

Oh, and it can't hurt to call your pdoc to discuss the symptoms that are worrying you.

Good luck!

-Blue




I was put on Pristiq yesterday to help with depression that had not been fully helped by Paxil I was taking I took Paxil for GAD and Panic Disorder as well as Xanax 3 times a day (which I've heard can worsen depression). According to my doctor Paxil is mainly for anxiety were Pristiq is supposed to help depression more so. I was also on Trazadon for insomnia............ Seems like I am being put on more and more meds to combat the side effects of meds then put on more to combat the side effects of the drug I went on to combat other side effects. But I will take the meds to combat the horrible anxiety and depression To me it's worth it. Anyways back to Pristiq last night was the first night taking it I could not sleep for the life of me after 3 xanax (.5 each) and a trazadon I wasn't even a little drowsy. I did not make it to sleep until 5 and unfortunately had to wake up at 9 for class. The good thing about it is that I am still not tired. I did get a little nausea about and hour after taking it tonight I will try taking it with food hope that helps. Not in the best mood today tho having a down day but I am going to associate that with the lack of sleep. Hopefully when the insomnia subsides I will start to feel better. I am a little peeved at my doctor however. I have told her time and time again I am a poor college student with no health insurance. From some research I did I found that Pristiq is 3.41 a pill. Hopefully the Pristiq will work tho and I can keep getting samples until the price comes down some or since its similar to effexor I will be able to switch once the patent runs out...... Anywho wish me luck And good luck to all out there

#45 Guest_Ladylee_*

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Posted 08 September 2008 - 07:43 PM

View PostBlueEyes, on Jun 12 2008, 06:30 PM, said:

Hi all-

I am new to this whole thing, as in diagnosed by a pdoc just yesterday. I took my first dose of Pristiq last night. I really have no clue about what to expect with it, and it kinda freaks me out that I can't be my usual research happy self with the drug since it is so new. Most things written about it have been negative, but I'm hoping that is because people are more likely to bitch about something that didn't work than they are to jump online and write about how much they loved it....right?? Anyway, I feel like a total test subject, and thought I should share. And since Pristiq isn't mentioned in too many places here, I can't just lurk the board in secret to find out what other people are experiencing.

Annnyway, I know it's a little early to be posting things about my experience, but I had such weird side effects with just the one pill, that I thought I should....
  • nauseous an hour after taking it
  • restless and unable to sleep
  • woke up dizzy and nauseous with a headache
  • chills off and on all day today
  • this weird feeling of being halfway to the point of barfing, but not. like the muscles in my throat were tightening like a gag reflex...it intensifies when I drink liquids. Has been going on all day. effin' weird!
  • just feeling hazy and out of it in general


of course I have nothing to compare it to...any opinions?

- s


#46 Guest_lADYLEE_*

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Posted 08 September 2008 - 07:58 PM

EFFEXOR VS PRESTIQ

View PostSorcy, on Sep 8 2008, 12:41 PM, said:

View PostBlueEyes, on Jul 22 2008, 07:09 AM, said:

View Poststrachml, on Jul 21 2008, 10:13 PM, said:

Hi everyone! :P

I was diagnosed with Generalized Anxiety Disorder and Panic Disorder in January 2002. I was on paxil (paroxetene) for about 5 1/2 years, which obviously worked pretty well, but I thought maybe trying a different drug would aleiviate some of the minor side effects I had (weight gain, pretty much no sex drive, etc). I tried lexapro for 2 months (not enough time to notice any change), then was switched to Effexor XR to also help treat a chronic pain problem. In addition to the GAD and PD, I have a fear of flying that I use ativan for.

I was fine on Effexor XR-- it didn't noticably help the pain problem, but anxiety was fairly non-existant. The high dose I worked up to (300mg) was great for when I flew (with the addition of the ativan I took a couple hours before the flight, it pretty much knocked me out, which is the best thing to happen when I fly haha!). I went back down to 225mg due to a little moodiness, and was still fine. UNFORTUNATELY, around the time I started Effexor (this past Jan) I also started having horrible acne breakouts (I've struggled with mild-persistent acne for 11 years, but this was much noticably worse :wtf: ). I blamed it on new birth control at first, but having been off that for about 3 months and still having the horrible acne... I realized that the Effexor may be the culprit (doing Yahoo searches, I saw that I may not have been the only one! But it seems like a pretty rare side effect). The acne was/is causing me problems, so I went back to the doc again...

My doc suggested Pristiq, saying it was the same compounds as Effexor, but seems to nix the side effects (seems too good to be true to me??)-- I was wary, but said I'd try it. I've taken it for 3 nights now, and I'm notiably more anxious. I hadn't felt the unexplained "everyday anxiety" (explained: e.g. forgetting to take my pills at night, or having to fly, etc.) for a long time. So this is definitely not a good sign to me. Sure, maybe it'll help the acne problem and not cause weight gain, which is great!!! But ultimately, I'm trying to not have anxiety/panic attacks here!!!!

I didn't have any problems when I started Effexor XR--- didn't feel like I needed time to ease into it. It seemed to start working right off the bat. My doc told me I didn't need to wean off Effexor to start Pristiq-- I could just go straight into 50mg from the 225 Effexor. I'm thinking of calling my doc tomorrow and telling him that its not going well so far.

I understand that it sometimes takes a while to really work, but dealing with the anxiety is really posing a challenge for me since I've pretty much been without it for a while.

I was seriously considering going back on Paxil... I didn't gain an exorbitant amount of weight, and I can deal with decreased/non-existant sex drive, even though it sucks. Or even lexapro since I didn't get a good feel for that one. Effexor did the same thing paxil did for me in terms of anxiety, but I'd rather deal with some weight gain than worsened acne (mind you, I still have the mild acne anyway!). BLAH!!!! :violin:

Any suggestion????? I would appreciate any ideas :)


I would give it a little more time unless it is completely unbearable. I'm no expert, but most of the side effects I experienced would last for a few days to a week, then they would be gone. Of course, everyone is affected differently. I had a couple of days of major anxiety as well, but that subsided. My pdoc gave me xanax to take as needed should any anxiety occur again, but it hasn't. I think it's worth sticking with it for a couple of weeks if you can. It might be worth it if it means you can avoid jumping back on the med-go-round. There are a couple of Pristiq threads for you to check out. I think there are a couple of people that take it for anxiety, you could always PM them and see how they are doing on it.

Oh, and it can't hurt to call your pdoc to discuss the symptoms that are worrying you.

Good luck!

-Blue




I was put on Pristiq yesterday to help with depression that had not been fully helped by Paxil I was taking I took Paxil for GAD and Panic Disorder as well as Xanax 3 times a day (which I've heard can worsen depression). According to my doctor Paxil is mainly for anxiety were Pristiq is supposed to help depression more so. I was also on Trazadon for insomnia............ Seems like I am being put on more and more meds to combat the side effects of meds then put on more to combat the side effects of the drug I went on to combat other side effects. But I will take the meds to combat the horrible anxiety and depression To me it's worth it. Anyways back to Pristiq last night was the first night taking it I could not sleep for the life of me after 3 xanax (.5 each) and a trazadon I wasn't even a little drowsy. I did not make it to sleep until 5 and unfortunately had to wake up at 9 for class. The good thing about it is that I am still not tired. I did get a little nausea about and hour after taking it tonight I will try taking it with food hope that helps. Not in the best mood today tho having a down day but I am going to associate that with the lack of sleep. Hopefully when the insomnia subsides I will start to feel better. I am a little peeved at my doctor however. I have told her time and time again I am a poor college student with no health insurance. From some research I did I found that Pristiq is 3.41 a pill. Hopefully the Pristiq will work tho and I can keep getting samples until the price comes down some or since its similar to effexor I will be able to switch once the patent runs out...... Anywho wish me luck And good luck to all out there



I was put on Prestiq after the Effexor failed to work for me..I have GAD and have had it for 7years..i have tried all SSRI and they aggravated my other health condition Vaso Vago Syncope.. a quick drop of BP and heart failure when passingout.. So I have now been forced to try the SNRI's Ive tri.. ed Lexapro...no good... Effexor as okay but he switched me to Prestiq instead of upping my dose of effexor.
Its been a fewmonths now...I weaned from Effexor to the Prestiq..that went well.. You definetely have to wean from one to the other on all SSRI or SNRI's...a three week wean atleast with adding the new med to the mix at the same time.. Sothe above person will have problems..Thats why the increased anxiety...levels are too low on both meds she is taking..
I do need to increase my prestiq only up to 100mg a day and starting to get anxiety again...so I attribute that to needing to be increased.
It is important to note...EFFEXOr will RAISE your BP...as well as Prestiq...but not as bad as effexor...which is okay for me since I have a low bP condition anyway.
Ive had no side effects from the Prestiq at all..NONE.. I think once the right dose is reached I should be good with this...If not I'll go back to EFFEXOR and increase my dose I was taking 185mg a day and the dr. thought that was a high dose?? But I read it takes sometimes a dose of atleast 250mg to be therapeutic..

Good Luck to ya all..
Lisa

#47 Guest_e_*

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Posted 20 September 2008 - 01:02 PM

View Postalex, on Jun 17 2008, 02:14 PM, said:

View PostBlueEyes, on Jun 17 2008, 07:39 AM, said:

oh. my. god. the insomnia!


I use melatonin to induce sleep. You can get it in the vitamin section of most stores.

I usually take it pretty early on -- like 8 or 9PM to get to bed by midnight. It's safe stuff, since melatonin is naturally occuring in the body anyway, and is the very thing that regulates sleep. It doesn't "knock me out," but makes me drowsy. A true insomniac can push through the effects of even melatonin, so you have to make an effort to give into the drowsiness.

In general, insomnia sucks ass. It does so with a high-power vacuum style. I wish there was a good solution for it, because I get hit by insomniac phases many times per year. The down side to almost any sleep aid is that it can keep you sleeping longer than you want, and make it difficult to wake up. So, take it very early in the evening -- before 9PM, and help it by TRYING to sleep, not trying to stay awake and fighting the effect.


#48 Guest_e_*

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Posted 20 September 2008 - 01:02 PM

View Poste, on Sep 20 2008, 12:02 PM, said:

View Postalex, on Jun 17 2008, 02:14 PM, said:

View PostBlueEyes, on Jun 17 2008, 07:39 AM, said:

oh. my. god. the insomnia!


I use melatonin to induce sleep. You can get it in the vitamin section of most stores.

I usually take it pretty early on -- like 8 or 9PM to get to bed by midnight. It's safe stuff, since melatonin is naturally occuring in the body anyway, and is the very thing that regulates sleep. It doesn't "knock me out," but makes me drowsy. A true insomniac can push through the effects of even melatonin, so you have to make an effort to give into the drowsiness.

In general, insomnia sucks ass. It does so with a high-power vacuum style. I wish there was a good solution for it, because I get hit by insomniac phases many times per year. The down side to almost any sleep aid is that it can keep you sleeping longer than you want, and make it difficult to wake up. So, take it very early in the evening -- before 9PM, and help it by TRYING to sleep, not trying to stay awake and fighting the effect.



#49 Guest_Tbell_*

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Posted 21 September 2008 - 06:19 PM

Hello all. I have been very surprised that I havent seen many negative responses online to pristiq. I recently forced myself to go in and get on something for anxiety, panic attacks, and depression, and my doctor threw Pristiq at me. I HAVE NEVER HAD SUCH AWFUL SIDE EFFECTS! I was a nervous wreck, hands shaking, insomnia, irritability, stomach upset, headache, my teeth were clenching- I felt like I had done 10 lines of coke or something. I had to explain to my office staff that I was taking new medication because I was so crazed. I toughed it out for 4 days and called my doctor and BEGGED her to prescribe something else. She switched me to Zoloft, which has had no side effects at all- except I still wake up in the middle of the night, but not freaking out like I did with Pristiq. I think this may be great for some, but definately didnt work well with my system. I am prone to having panic attacks, I definately dont want a drug that causes additional episodes-
Just wanted to post in case someone else has similiar symptoms- TALK TO YOUR DOCTOR!!!

#50 Guest_the red_*

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Posted 24 September 2008 - 02:32 PM

Hi Blue Eyes,

I just though I'd post, as your description on how you immediately felt on Pristiq mirror my symptoms exactly, so it's definitely helpful.
It's day 4 and I no longer have a metal taste in my mouth, my stomach is not in knots and I don't feel so dizzy. But I am TIRED. I've been trying to get sleep and taking it easy when I get home from work. But I am hoping it will subside soon.
I'm also on 300 mg of Lamictal for bipolar (the other half of the symptoms). I haven't had any anxiety or suicidal thoughts or crying, but I've felt very hazy, tired and generally emotionless. Will this subside?

Suggestions anyone?

thanks!

#51 User is offline   the red 

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Posted 24 September 2008 - 02:39 PM

Hi guys, just created an account, so re-posting this -- sorry!!

View Postthe red, on Sep 24 2008, 02:32 PM, said:

Hi Blue Eyes,

I just though I'd post, as your description on how you immediately felt on Pristiq mirror my symptoms exactly, so it's definitely helpful.
It's day 4 and I no longer have a metal taste in my mouth, my stomach is not in knots and I don't feel so dizzy. But I am TIRED. I've been trying to get sleep and taking it easy when I get home from work. But I am hoping it will subside soon.
I'm also on 300 mg of Lamictal for bipolar (the other half of the symptoms). I haven't had any anxiety or suicidal thoughts or crying, but I've felt very hazy, tired and generally emotionless. Will this subside?

Suggestions anyone?

thanks!

dx: bipolar disorder, S.A.D.
for ups: lamictal (100 mg x 3)
for downs: pristiq (50 mg x 1)
recently weaned off Neurotin (300 mg x 2)

currently seeking new therapist
alternative: dr. bach's flower essences make my life.
light box therapy for S.A.D.

#52 User is offline   BlueEyes 

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Posted 24 September 2008 - 05:55 PM

Quote

Hi Blue Eyes,

I just though I'd post, as your description on how you immediately felt on Pristiq mirror my symptoms exactly, so it's definitely helpful.
It's day 4 and I no longer have a metal taste in my mouth, my stomach is not in knots and I don't feel so dizzy. But I am TIRED. I've been trying to get sleep and taking it easy when I get home from work. But I am hoping it will subside soon.
I'm also on 300 mg of Lamictal for bipolar (the other half of the symptoms). I haven't had any anxiety or suicidal thoughts or crying, but I've felt very hazy, tired and generally emotionless. Will this subside?

Suggestions anyone?

thanks!


Hi red-

From the bulk of the experiences people have posted here (including myself), the sleeplessness and/or tiredness will subside. However, it may take 6 to 8 weeks for all or most of the side effects to go away. The other thing my pdoc mentioned is that some people do better taking it at night (like me) and some have to take it in the morning. I would say that if it lasts past the 6 weeks, you might want to ask your pdoc about changing the time you take it. Also, I have noticed that I have to get a full 8 hours of sleep now instead of the 6 hours I was getting before the meds or else I will be tired all day.

It doesn't sound like you have had any unbearable side effects and you are probably going through the worst of it now. See if you can stick with it a little longer. Keep us posted on your positive and negative experiences. There was hardly any info anywhere when I started taking it, so I'm hoping others can find our posts and see if what they are going through is "normal". :)

-Blue

"Fortunately, I'm adhering to a pretty strict, uh, drug, uh, regimen to keep my mind, you know, uh, limber."
-The Dude

dx: major depressive disorder
rx: pristiq 50mg. xanax for my freakouts

other junk:
daily - gigantic multi vitamins, 1200mg omega 3-6-9, chromium picolinate 200mcg
I'm feelin' good!

#53 User is offline   the red 

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Posted 25 September 2008 - 04:47 PM

Hi Blue,

Thanks for getting back to me so soon! Side effects were pretty bad at first (very sick stomach for the first few days, exhaustion, no appetite, dizziness, completely brain-dead) but getting a bit better every day. (I'm on Day 5 here.) I have definitely been getting more sleep and I take the 50 mg at night (so to avoid any nausea) and fall asleep pretty fast but wake up many times during the night. =(

I'm just coming off 600 mg of Neurontin and am taking 300 mg of Lamictal (50 in the day and 250 at night) to try to have as little tiredness as possible during the day. I still get very tired midday on the Pristiq, but have been trying to combat it with Emergen-C drinks and espresso.

Other than the tiredness I haven't felt depressed or irritable for the most part (which I was). I feel pretty even, but I feel very subdued (which is obviously strange for someone bi-polar). Hopefully I'll get some of my energy back soon, I'm a very energetic person and am missing my fervor for life. Also I have no sex drive whatsoever. Although it's not a huge issue in my mind, as I'm still getting accustomed just to basic functioning on the meds -- I'd like it to improve. My boyfriend's been very helpful and attentive so far, so we'll see how that progresses.

Thanks all for your comments!

Red
dx: bipolar disorder, S.A.D.
for ups: lamictal (100 mg x 3)
for downs: pristiq (50 mg x 1)
recently weaned off Neurotin (300 mg x 2)

currently seeking new therapist
alternative: dr. bach's flower essences make my life.
light box therapy for S.A.D.

#54 User is offline   coffeeisntbreakfast 

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Posted 27 September 2008 - 10:42 AM

Hello, I'm new here too. I have experienced similar effects as you. I have felt nauseaus and then get weepy at the same time, or just weepy in general. Sometimes I feel good. I get headaches I can't get rid of but that's not new to me. I do get stomach pains almost every day and feel dizzy. I take Pristiq with Wellbutrin, Topamax and Lamictal. I used to take Effexor XR and I want to go back on it, but my doc wants me to give Pristiq a fair shot. I think I'm having Effexor withdrawal and side effects of Pristiq at the same time. Most every day I have bouts of nausea and stomach aches. Does anybody else have this too, plus tiredness. I've been taking this over a week and just upped to 100 mgs.

Thanks, Lisa


View PostBlueEyes, on Jun 12 2008, 07:30 PM, said:

Hi all-

I am new to this whole thing, as in diagnosed by a pdoc just yesterday. I took my first dose of Pristiq last night. I really have no clue about what to expect with it, and it kinda freaks me out that I can't be my usual research happy self with the drug since it is so new. Most things written about it have been negative, but I'm hoping that is because people are more likely to bitch about something that didn't work than they are to jump online and write about how much they loved it....right?? Anyway, I feel like a total test subject, and thought I should share. And since Pristiq isn't mentioned in too many places here, I can't just lurk the board in secret to find out what other people are experiencing.

Annnyway, I know it's a little early to be posting things about my experience, but I had such weird side effects with just the one pill, that I thought I should....
  • nauseous an hour after taking it
  • restless and unable to sleep
  • woke up dizzy and nauseous with a headache
  • chills off and on all day today
  • this weird feeling of being halfway to the point of barfing, but not. like the muscles in my throat were tightening like a gag reflex...it intensifies when I drink liquids. Has been going on all day. effin' weird!
  • just feeling hazy and out of it in general


of course I have nothing to compare it to...any opinions?

- s


#55 User is offline   BlueEyes 

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Posted 27 September 2008 - 11:01 AM

Hi Lisa, welcome to CB!

The worst of the side effects were over for me by the end of week two. Hopefully, that will be the case for you too.


Red-

I got my energy back and was able to start sleeping by the end of my second week. Also, the brain zaps and subdued feeling also stopped. I also made an effort to change my diet by eating foods that keep my blood sugar even and that helped a lot (and cut out a lot of sugary foods). As for the sexual side effects, my depression had affected my self-esteem so much that once the depression was under control, my self-esteem has improved a ton. I actually feel more confident and sexual than before. Hopefully, any of the sexual side effects you have will subside, but I have heard that they are common. But I'm guessing that not being depressed may be worth dealing with the sexual side effects?


Good luck to both of you!

-Blue

"Fortunately, I'm adhering to a pretty strict, uh, drug, uh, regimen to keep my mind, you know, uh, limber."
-The Dude

dx: major depressive disorder
rx: pristiq 50mg. xanax for my freakouts

other junk:
daily - gigantic multi vitamins, 1200mg omega 3-6-9, chromium picolinate 200mcg
I'm feelin' good!

#56 User is offline   Isolde 

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Posted 27 September 2008 - 11:14 AM

I have to say that I was way way depressed. I had lost 50 pounds (good side effect, though) because I was too depressed to eat, clean the house, cook or do much of anything. I saw around in a depressed stupor all the time. I think that depending on how depressed you are, is also how much Pristiq will help you or not, side effects or not.

Like I said, I was afraid I was going to have to be hospitalized if I kept on going like I was. Pristiq saved my life, surely as anything else physical would have put me in a hospital. My hormones, also, changed. I went through menopause and everything got whacked out because of it. Bipolar is tough on menopausal women and vice-versa.
Bipolar since my twenties.
Hypothyroid since my thirties.

Currently taking Seroquel,200 per night.
Klonopin 0.10 at night.
Ritalin SR 20 mg am.
Synthroid 137 mcg a day.
Pristiq 40 mg am (new)

I've had back surgery in my twenties; a hip replacement 4 years ago, a c-section at 36,
I am currently extremely exhausted/foggy thinking, depressed.
I am feeling much better, alive and active and able to do activities of daily living.

#57 User is offline   the red 

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Posted 30 September 2008 - 09:42 AM

Hi Blue eyes and all,

CB has been acting up lately, so sorry for the delay on the post. So far I am on one week and a day of Pristiq.

Don't want to speak too soon, but the sex drive has GREATLY improved overall -- which is amazing because it's been a big roadblock for almost my entire relationship with my BF (3 years!). I feel so much more comfortable, joyful and in the present moment as opposed to so often "in my own head" in the past. Physically, I am not having climaxes the way I used to, they can be delayed or underwhelming. But at least my sex drive and the impetus is there to work around these new issues!! Unfortunately, my monthly visit from Mother Nature cut our newly found tryst short, so I'll be reporting back to see if the situation is the same next week.

By now I'm not feeling the loss of appetite and chronic nausea in the day hours and significantly less tired than when I began. I take the Pristiq right before bed so as to avoid nausea. Although I am falling asleep quickly, I do wake up several times during the night with nausea. I am often able to have some bread and water and fall back asleep though. Perhaps I will try the melatonin soon, I keep forgetting.

Definitely hoping to get some more of my daily energy back, but that too is improving. It's only been a week and I have already felt a significant improvement on my whole outlook on life. I am bipolar, but was always on mood stabilizers and never an anti-depressant. I never realized how much I was missing! I am significantly less irritated, tearful and hopeless than before.

Thanks for your help Blue Eyes, your support and positive experiences (congratulations on the elopement!!) have really been a comfort and motivation for me.

Thanks all!

Red
dx: bipolar disorder, S.A.D.
for ups: lamictal (100 mg x 3)
for downs: pristiq (50 mg x 1)
recently weaned off Neurotin (300 mg x 2)

currently seeking new therapist
alternative: dr. bach's flower essences make my life.
light box therapy for S.A.D.

#58 User is offline   coffeeisntbreakfast 

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Posted 30 September 2008 - 11:22 AM

Hello, thanks all for sharing your experiences. My stomach aches are going away which is good. I'm teary on and off still. I've been taking 100mg of Pristiq for 4 days. My Wellbutrin was upped to 150 mg. Lamictal stays at 300mg, Topamax at 100mg and Klonopin at 1.5 mg. I'm not tired during the day as much but don't have any motivation yet to get up and do anything. I haven't showered for 3 days but I have gotten out one day and ran errands. I feel more subdued still, slowed down. I hope this passes. I am going to force myself to get off the couch now and take a shower and clean up the place a bit as I'm going out of town for awhile. My doctor was hoping my sex drive would come back but there is no hint of it yet. Luckily my husband and I don't see each other every day! It's More like 1 week per month because we live in different cities because of our jobs. I was taking 300 mg of Effexor XR with the Wellbutrin and I did feel much better then, or so I thought. I'll give Pristiq more time because my doc has had so many good responses to it but I'm still discouraged because of the lack of motivation and general down in the dumps feelings. My sugar cravings have gotten better which I'm happy about.

If anyone would like to comment on anything I've shared here, please feel free to do so, I could use any insight you can give me,

Thanks all,

Lisa

#59 User is offline   BlueEyes 

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Posted 01 October 2008 - 03:09 AM

Red-
You're welcome! Glad to hear everything is improving. The idea of meds scared the s&*t out of me, and CB really helped me feel like I wasn't alone. I hope you continue to post updates.

Lisa-
Hang in there, it really does take some time. The first 2 weeks sucked for me, then everyday I felt better and better. Feel free to PM me if you have questions or if you need a motivational pep talk.

:)
-Blue

"Fortunately, I'm adhering to a pretty strict, uh, drug, uh, regimen to keep my mind, you know, uh, limber."
-The Dude

dx: major depressive disorder
rx: pristiq 50mg. xanax for my freakouts

other junk:
daily - gigantic multi vitamins, 1200mg omega 3-6-9, chromium picolinate 200mcg
I'm feelin' good!

#60 User is offline   the red 

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Posted 01 October 2008 - 09:46 AM

Hi Lisa,

I would just say to give yourself a break. You've only been on the meds for 4 days. My first 4 days all I did was eat bread and water for the nausea, go to work and come home and go to sleep. I could barely make it through my first few days -- much less even THINK about sex! You're also on a lot of other meds and so probably everything is a little out of whack. Just give yourself some time before you really take into account whether or not the Pristiq is working. It took me about a week just to feel like I could cope with my appetite and my job and everything. I'm at a week and a half and I'm still having trouble with the sleeping and still feeling kind of tired, but many of my other discomforts are gone (not to mention my crying, irritability and hopelessness, thankfully) and every day gets better. :)

This post has been edited by the red: 01 October 2008 - 09:47 AM

dx: bipolar disorder, S.A.D.
for ups: lamictal (100 mg x 3)
for downs: pristiq (50 mg x 1)
recently weaned off Neurotin (300 mg x 2)

currently seeking new therapist
alternative: dr. bach's flower essences make my life.
light box therapy for S.A.D.

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