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So, just got back from the pdoc's with samples for 30mg Cymbalta. I am already taking 50mg Paxil for severe OCD, and he thought that the Paxil wasn't doing enough for my norepinephrine(?). Has anyone else here taken a combo of paxil + cymbalta or something similar with multiple AD's? Any side effects or other symptoms I should look out for? I hope this does something for my OCD.
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Paxil & Cymbalta
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#1
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Posted 11 March 2010 - 12:39 PM
Dx: Severe OCD (with poor insight), Trichotillomania, GAD, Schizoaffective Disorder (Depressive type);
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
MultiQuote
#2
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Posted 11 March 2010 - 12:43 PM
Hi Alien 
I'm still alive...lol. Although I don't have a THING to say about Paxil and Cymbalta...I hope for your sake that it helps you because I know your obsessive thoughts cause you a lot of distress. Let me know how it works out...
I'm still alive...lol. Although I don't have a THING to say about Paxil and Cymbalta...I hope for your sake that it helps you because I know your obsessive thoughts cause you a lot of distress. Let me know how it works out...
My "issues": Evaluation in progress...
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
#3
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Posted 11 March 2010 - 12:47 PM
Hey you! How have you been? Did you end up going to the hospital? I haven't seen you around in a few days and I'm wondering how you're doing.
How have you been? Did you end up going to the hospital? I haven't seen you around in a few days and I'm wondering how you're doing.
Dx: Severe OCD (with poor insight), Trichotillomania, GAD, Schizoaffective Disorder (Depressive type);
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
#4
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Posted 11 March 2010 - 12:58 PM
I will write you a note about it so I don't dominate your post; you probably want replies about Paxil/Cymbalta still
My "issues": Evaluation in progress...
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
#5
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Posted 11 March 2010 - 08:22 PM
Paxil and Cymbalta both do serotonin reuptake inhibition. since you're on a fairly high paxil dose there might be some risk of serotonin syndrome when combining it with Cymbalta unless the plan is to taper off the paxil fairly soon after starting the Cymbalta. Be aware of the signs of serotonin syndrome so you can get yourself to the ER if that happens.
http://en.wikipedia....otonin_syndrome
http://en.wikipedia....otonin_syndrome
De-gnosis: ADD, recurrent depression (or maybe bpII in the guise of such), Asperger's, OCD, social anxiety
Today's Pill Menu: Dexedrine, Wellbutrin (Budeprion), Topamax, Risperdal, clonazepam
Like other moderators and staff of crazyboards.org, I am not a health care professional. You have no way of knowing that I am not talking out my ass. Please do your own homework before making any health related decisions.
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#6
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Posted 11 March 2010 - 09:12 PM
Yikes! Thanks for the tip.
Dx: Severe OCD (with poor insight), Trichotillomania, GAD, Schizoaffective Disorder (Depressive type);
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
#7
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Posted 11 March 2010 - 09:34 PM
That is scary. I wonder why he gave it to you then. Maybe it'll be okay, I'm sure he knows about serotonin syndrome and stuff. Btw I wrote you
My "issues": Evaluation in progress...
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
My meds: Pristiq 50 mg, Klonopin 0.5 mg as needed
Past meds: Celexa, Rozerem, Vyvanse, Zoloft, Lexapro, Abilify, Trazodone, Seroquel, Geodon, Anafranil, Saphris, Cogentin, Risperdal
#9
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Posted 23 April 2010 - 11:39 AM
Just want to pipe in that I was on both meds at the same time at around the same cumulative dose and didn't have a problem with Serotonin Syndrome. So definitely be on the lookout for it, but don't assume that you'll get it either.
_ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _
Dx: Major Depression w/ Dysthymia and Panic Disorder
Pdoc's Theory Dx: Bipolar NOS
Rx : Amitriptyline 100mg, Abilify 30mg, Lamictal 300mg, Neurontin 900mg, Trazodone 100mg, Concerta 27mg, Armour Thyroid 120mg (2 gr), Nadolol prn, Xanax prn, Omega-3, L-Dopa, L-Tyrosine, B-Complex, Skelaxin prn, Probiotic
EXRx : Zoloft, Seroquel, Wellbutrin, Prozac, Lithium, Lamictal, Remeron, Lexapro, Abilify, Zyprexa, Geodon, Cymbalta, Paxil, Sonata, Lunesta, Effexor, Metadate, Risperdal, BuSpar, Ambien, Invega, Tegretol, Nortriptyline, Desipramine, Deplin
I do whatever my rice krispies tell me to.
~~~~~~~~~~~~~~~~~~~
"All of life is a struggle. It's a struggle just to get out of bed in the morning. You're fighting gravity all day long." - Richard Rose
_ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _. _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _
Dx: Major Depression w/ Dysthymia and Panic Disorder
Pdoc's Theory Dx: Bipolar NOS
Rx : Amitriptyline 100mg, Abilify 30mg, Lamictal 300mg, Neurontin 900mg, Trazodone 100mg, Concerta 27mg, Armour Thyroid 120mg (2 gr), Nadolol prn, Xanax prn, Omega-3, L-Dopa, L-Tyrosine, B-Complex, Skelaxin prn, Probiotic
EXRx : Zoloft, Seroquel, Wellbutrin, Prozac, Lithium, Lamictal, Remeron, Lexapro, Abilify, Zyprexa, Geodon, Cymbalta, Paxil, Sonata, Lunesta, Effexor, Metadate, Risperdal, BuSpar, Ambien, Invega, Tegretol, Nortriptyline, Desipramine, Deplin
I do whatever my rice krispies tell me to.
~~~~~~~~~~~~~~~~~~~
"All of life is a struggle. It's a struggle just to get out of bed in the morning. You're fighting gravity all day long." - Richard Rose
_ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _. _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _ . _
#10
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Posted 23 April 2010 - 12:47 PM
Cetkat, on 23 April 2010 - 11:39 AM, said:
Just want to pipe in that I was on both meds at the same time at around the same cumulative dose and didn't have a problem with Serotonin Syndrome. So definitely be on the lookout for it, but don't assume that you'll get it either.
Thanks. I think my pdoc believes that I'm getting slightly manic though. I'm currently on Paxil 20mg and Cymbalta 60mg. I want to go up to 90mg on the Cymbalta. I really don't care what he does with the Paxil.
Dx: Severe OCD (with poor insight), Trichotillomania, GAD, Schizoaffective Disorder (Depressive type);
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
#11
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Posted 23 April 2010 - 01:13 PM
I'm not sure why he'd give you more SSRIs if there's a chance of you being manic, unless he's also raising your mood stabilizers.
Serotonin syndrome is something to keep an eye on definitely, but it's not guaranteed.
Serotonin syndrome is something to keep an eye on definitely, but it's not guaranteed.
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"I sat up late and I watched you sleep. You said you'd waited 30 years for me."
“Better to reign in hell than serve in heaven.”
#12
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Posted 23 April 2010 - 01:52 PM
dianthus, on 23 April 2010 - 01:13 PM, said:
I'm not sure why he'd give you more SSRIs if there's a chance of you being manic, unless he's also raising your mood stabilizers.
Serotonin syndrome is something to keep an eye on definitely, but it's not guaranteed.
Serotonin syndrome is something to keep an eye on definitely, but it's not guaranteed.
Well, he's added Geodon and it's going up soon. I'm pretty sure that Geodon is anti-manic.
I need high doses of SSRI's b/c of my OCD, so I guess I may have to risk mania for now. My OCD is pure hell, worse than my other conditions even.
Dx: Severe OCD (with poor insight), Trichotillomania, GAD, Schizoaffective Disorder (Depressive type);
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
Current Rx meds: Prozac 80mg, Geodon 240mg, Cogentin 1mg, Klonopin 0.5mg 4 X daily, Trazodone 50mg - 100mg nightly;
Ex-Rx and OTC meds: Cymbalta 120mg, Paxil 20mg, Abilify 5mg, Zyprexa 2.5mg, Ativan 0.5mg 3 X daily, Inositol, GABA;
How I'm doing: Feeling great! Almost in remission for both OCD and Schizoaffective Disorder. Still struggling with general anxiety, however.
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