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Seroquel in the morning?


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#1 enlightened_plutonian

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Posted 17 May 2012 - 02:46 PM

I've always taken all my Seroquel at night, and that is good because it sedates me. But for some reason my pdoc decided to increase my dose to 800mg, as 400 in the morning and 400 in the night. He didn't want me taking it all at once.

Of course I am worried that this will turn me into a zombie. Seroquel sedates me and I am worried about taking it in the morning as I need to be functional during the day. I don't work or anything, but keeping busy is one of my coping strategies and I don't want to be stuck in bed all the time.

So does anyone have any tips to not be affected by the sedation when I take the morning dose? Would exercise help, or fresh air? Or anything I haven't thought of?

Does anyone take Seroquel in the morning and it not bother them?

Thanks in advance.
- enlightened_plutonian
Current diagnosis = psychosis NOS
History = depression (remission since April 2009), SI (remission since April 2009), alcohol abuse (remission since March 2007)
Past false dx = BPD (only symptom I had was SI), schizophrenia (I was very sleep deprived at the time)
Also have diabetes and pain issues (undiagnosed) and hayfever (April - June)

Current meds = Seroquel 800mg XR (as 400 in the morning and 400 in the night)
Also on insulin and Microgynon

I am not deluded, I just don't agree with your reality!


#2 gizmo

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Posted 17 May 2012 - 03:19 PM

I took 200 mg or the IR during the day, and 200mg at bedtime. While it didn't specifically make me sleep, it did make me very lethargic the entire day.

I found that getting off the couch every half hour or so to do anything, even if it was just to use the bathroom or get a drink, helped me feel a little better. I tried walks, but I'll be honest with you, I still can't really get motivated to do that.

What I found made me the sleepiest was reading. I just couldn't focus and I would find myself drifting away, tired and bored as hell and unfocused.

I hope I've helped you a bit. I had to get off the quel because of the all day lethargy, so I feel you.
Diagnosis: BP I with Psychotic Features, GAD, ADHD, Chronic Migraines, various physical stuff.
Meds Currently On: Depakote 2000 mg, Risperdal 8 mg, Latuda 80 mg, Prozac 60 mg, Vyvanse 70 mg, Propranolol 40 mg BID, Klonopin 2 mg BID PRN
Meds Sort-Of Mental Related: Lipitor 40 mg, Zofran 4 mg PRN, Fioricet PRN, Stadol PRN, Botox received on 8/16/13

I post on an iPhone, so please forgive grammatical errors or strange word inclusions. It's the auto correct!

#3 bpladybug

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Posted 17 May 2012 - 03:33 PM

I have to be able to function and work, talk on the phone, etc.
I take a certain dosage of ER in the exening.
Then towards bed time I take some regular Seroquel which helps with sleep.

Total 400 mgs.
300 mgs extended release in the evening
100 mgs regular before bedtime

This way I always have it in my system. The only reason I would take
additional 'quel in the morning would be if I was manic.

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Bipolar 1
Treatment: 900 mgs Lithium, 900 mgs Neurontin, 400 mgs Seroquel, Xanax prn, Temazepam, fish oil, vitamins, Vit. D 5, 000 IU, exercize, some talk therapy and CBT Therapy. Exercize helps as does the Light Box; 30 mins every morning. I also have physical health challenges.


#4 Chiaroscuro

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Posted 17 May 2012 - 04:22 PM

Personally, I find any from of Seroquel massively sedating. Originally my GP wanted me to take the IR version both morning & night, but it made me a zombie. I now take the the XR version at night.

The only thing I found helpful in trying to combat the sedation during the day was making sure I was a bit cold rather than warm (temperature-wise), being a bit cold seemed to help me stay a bit more awake.

I'm sorry I can't give you any better information :(

"Visual bruises can be covered with makeup. But down to the core I'm all bruises" Majandra Delfino.
* These are just my personal opinions/ experiences/ things that have worked for me over time, they may or may not work for you, I'm not a medical professional. Seek medical advice before undertaking any exercise, medication, diet, or any major lifestyle changes *
Chiaroscuro: basically put; a juxtaposition of light & dark, commonly used in Art.
Current Dx:
Bipolar I -Rapid Cycling without psychosis-| Generalised Anxiety Disorder (GAD)| Asthma| Irritable Bowel Syndrome (IBS)| Self Dx: ED/ Calorie restriction/ Binging/ Over Eating/ Slight Purging/ Over Exercising /Fasting/ Abuse of laxatives/ Disordered Eating/ Self Injury/Harm.

Previous Dxs:

BPII

Rapid Cycling BPII
Major Depressive Disorder (MDD)

Some traits of some sort of personality disorder (Pdoc never said which PD he felt it was)

Lack of coping mechanisms

Impulse control issues
Current Rx:

Lamictal (Lamotrigine) 100mg AM| Zactin/Lovan/Prozac (fluoxetine) 20mg AM|Valium (Diazepam) 2mg tablets prn|Eutroxsig (levothyroxine as thyroxine sodium) 50mg AM 5 days & 100mg 2 days a week|Symbicort Inhaler 200mcd/6mcg prn|Nexium (esomeprazole) 20mg AM & PM |Zantac (ranitidine) prn|~for Hayfever~ Telfast (Fexofenadine) 180mg AM OR Zyrtec (cetirizine) 10mg AM 
Previous Rx:
Lithium| Seroquel XR & IR (Quetiapine) | Epilim (Sodium Valproate)|Pristiq (Desvenlafaxine)| Effexor XR (Venlafaxine)| Aropax (Paroxetine Hydrochloride)| Cipramil (Citalopram Hydrobromide)

"Think of the solution, not the problem" ~Richard Rahl~ -Terry Goodkind's Sword of Truth Series-


#5 claire466

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Posted 17 May 2012 - 04:57 PM

I only take 25g 4 times a day, and at night i take a 100mg one. And i don't feel anything from it.
Social anxiety disorder/Depression.

meds= 150mg Venlafaxine, 200mg Seroquel.


If you don’t like something change it; if you can’t change it, change the way you think about it. ~Mary Engelbreit



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#6 konings

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Posted 17 May 2012 - 05:55 PM

I take 150mg in the morning and night and unfortunately I have to laugh in the face of seroquel cause it doesnt even sedate me anymore (I liked the sedation). If I didnt take seroquel twice a day id probably spend at least several good hours every day being psychotic. Ultimately its up to you if you want to change your treatment regime.

#7 hallowedink

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Posted 17 May 2012 - 07:17 PM

Maybe you could speak to your Pdoc about not splitting the dose equally - ie taking something like 600mg at night and 200mg in the morning? I don't know if that would change anything... I don't really get any sedation from the Seroquel, but I once missed my dose at night, so took it the next morning instead, and I was ridiculously groggy from it.

I'm afraid that I don't really have any advice. The best thing I can suggest is speaking to your Pdoc about your concerns, or if you can't speak to him then maybe a pharmacist or case manager? They might be able to advise you on what to do.

My Brain Salad: BPD, MDD, Insomnia, Anorexia Nervosa, "very likely" C-PTSD, Migraines
What they give me for it: Seroquel 300mg, Wellbutrin 300mg, Lofepramine 140mg, Pizotifen 3mg, Naproxen PRN, Zopiclone PRN, Valium PRN`

Have also dealt with: Panic Disorder (now in remission), Self-harm (stopped ~4 months, but still relapsing occasionally)


#8 g8orgirl

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Posted 17 May 2012 - 07:21 PM

I'm 800mgs of Seroquel and I take it all at night. I would ask your pdoc why he/she doesn't want you taking it all at once. I know for me, I could not take the Seroquel in the morning because I would be way too tired.
Schizoaffective - depressive type
Meds: Abilify 5 mgs, Effexor 75 mgs, Trazodone 100 mgs

#9 rowan77

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Posted 18 May 2012 - 01:36 PM

In the past I have taken 700mg IR and took 300mg in the morning and 400mg at night and once the initial sedation wore off I was ok. However, at that point in my life I was neither studying or working and was able to sleep til lunchtime and maybe if I had to be up early and be a well functioning member of society I might have had a problem.

I agree with Hallowedink about maybe taking the smaller dose in the morning. Also, I don't understand why you just can't take 800mg XR at night. It is an extended release formulation that is designed to be taken once daily. I'm sure your pdoc has his reasons for not wanting you to take it all at once, but I think I would question him if it were me......

DX: Bipolar Disorder, Social Anxiety Disorder

Current RX: Lithium Carbonate 800mg, Seroquel XR 800mg, Lamictal 100mg x2 daily, Procyclidine 5mg, prozac 40mg, Zopiclone 7.5mg PRN 

Also Yasmin 0.3/3mg for PCOS and Losec 40mg for Hiatus Hernia, Oesophagitis and Gastritis

 

Previous RX:
Anti-depressants: dothiepin, clomipramine, paroxetine, mirtazepine, lofepramine, venlafaxine, escitalopram, agomelatine
Anti-psychotics: thoridazine, risperidone, olanzapine, haloperidol, aripiprazole, chlorpromazine
Mood Stabilisers: carbamazepine, sodium valproate,
Anxiolytics: alprazolam, diazepam, lorazepam, clonazepam
Hypnotics: lormetazepam, temazepam, zolpidem, flurazepam
ECT: 6 Treatments in 2003; 11 Treatments in 2005

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#10 scatty

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Posted 18 May 2012 - 01:42 PM

I agree to ask your pdoc if you can take less in the a.m. and more in the p.m. If your insurance will cover it, the xr version might be an option, as rowntree said.

Dx:
Bipolar I & Anxiety.  Self diagnosed cunt.

My New (old) Meds: (previously these kept me the most stable)
Lithium ER 1350 mgs.
Lamictal 200 mgs.

Klonopin 2 mgs.

 

Practicing CBT, DBT, and ACT self-help therapy.

Crazy since the 80's!
 


#11 enlightened_plutonian

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Posted 18 May 2012 - 02:39 PM

Thanks all for the suggestions. I will see how I go at the weekend (I couldn't get to the pharmacy until today to get the extra pills). I plan to use exercise to keep me awake if I can. But if it is too much for me I will have to call my pdoc.
Current diagnosis = psychosis NOS
History = depression (remission since April 2009), SI (remission since April 2009), alcohol abuse (remission since March 2007)
Past false dx = BPD (only symptom I had was SI), schizophrenia (I was very sleep deprived at the time)
Also have diabetes and pain issues (undiagnosed) and hayfever (April - June)

Current meds = Seroquel 800mg XR (as 400 in the morning and 400 in the night)
Also on insulin and Microgynon

I am not deluded, I just don't agree with your reality!

#12 bluechick

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Posted 18 May 2012 - 03:01 PM

I have found that when a med is sedating there is nothing that can be done to combat it. I would just make it clear to your pdoc that you are not willing to live this way and ask what can be done. There is no reason for you to be turned into a zombie.

Dx: Bipolar Disorder I, ADD, BDD
Rx: Lamictal 300mg; Wellbutrin 300mg: Celexa 40mg
FAIL: Lithium; Geodon. Abilify


#13 enlightened_plutonian

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Posted 19 May 2012 - 04:12 PM

So I took the 400mg Seroquel this morning and did the extra exercise. I didn't notice anything until I had been in the library for a couple of hours (until about 3:30pm), when I felt like I was about to collapse whilst doing the supermarket shopping. Taking the bus home (about 4:30pm) I felt lethargic but was able to stay awake. When I got home (about 5pm) I realised I needed to go back to bed, and I felt a lot better after waking up.

This is ok for me at the weekend, but will cause difficulties during the week. But I am hopeful that once my body gets used to the dose change that I may feel a little better. If not I will definitely report back to my pdoc and see if I can go back to taking it all at night, but for now I will stick with the split dosage in the hope that I will feel better about it soon.

I will definitely be keeping up with the exercise, as that seemed to be a positive.

Thank you for all the responses.
Current diagnosis = psychosis NOS
History = depression (remission since April 2009), SI (remission since April 2009), alcohol abuse (remission since March 2007)
Past false dx = BPD (only symptom I had was SI), schizophrenia (I was very sleep deprived at the time)
Also have diabetes and pain issues (undiagnosed) and hayfever (April - June)

Current meds = Seroquel 800mg XR (as 400 in the morning and 400 in the night)
Also on insulin and Microgynon

I am not deluded, I just don't agree with your reality!

#14 Gearhead

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Posted 19 May 2012 - 04:24 PM

Maybe you could speak to your Pdoc about not splitting the dose equally - ie taking something like 600mg at night and 200mg in the morning?

Also, I don't understand why you just can't take 800mg XR at night. It is an extended release formulation that is designed to be taken once daily. I'm sure your pdoc has his reasons for not wanting you to take it all at once, but I think I would question him if it were me......


I find that even with the XR I do need to split the dose and take it twice daily to get the desired effect. But making the morning dose smaller if you find it sedating is probably a good idea. Also, I found the morning dose very sedating for about the first week, and then I got used to it. I do need to take it with food; a bowl of cereal is enough.

Bipolar I, sports fans. Autism spectrum. With just un soupçon of migraine...Crazy, but not irrational.

Give us this day our daily meds: 150 lamotrigine, 75 topiramate, 150 Seroquel XR, 100 Seroquel IR, 12.5 Ambien CR,
60 mgs Cymbalta

4000 i.u. Vit. D3
Azelastine nasal spray 2x/per nostril 2x daily
Etodolac 400 mgs 2x/daily and Votaren Gel 2 grams 2x/daily for joint pain NOS

Cyclobenzaprine and Midrin PRN

Past, failed attempts: Effexor XR, Celexa, amitriptyline, Depakote, escitalopram, Geodon, klonopin, ativan, bupropion, busipirone, lithium, trazodone, Lunesta, Rozerem, gabapentine, mirtazapine, Wellbutrin, Temazepam, Sonata


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