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If you miss a dose, then take it the following day

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#1 LexFlex



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Posted 12 July 2012 - 01:34 PM

Hi to everybody out there who are on AP's.. Lets say you miss a dose, but you take it the next following day. How do you feel? Usually if I miss one dose and take it the next day I don't notice much of a difference. But I'm suspicious my thinking will change somewhat slightly because of it. Its got me worried a bit.

#2 The Emperor

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Posted 12 July 2012 - 02:05 PM

If it happens once in a while, I'm okay. If it happens several days in the same week- not so much.

What do you mean you're afraid your thinking will change because of it?

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#3 Furious George

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Posted 12 July 2012 - 02:14 PM

I can go 2 days at the most without any noticeable changes. The 3rd day and shit starts going sideways. I bought at alarm clock that is set specifically for my med times, so I don't forget.

#4 sylvan


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Posted 12 July 2012 - 05:43 PM

Honestly, it depends on which med we're talking about. Some of them I notice pretty quickly. Others, it takes a week or more.

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#5 wj74



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Posted 12 July 2012 - 05:46 PM

I notice more of a difference missing the Lamictal than I do the seroquel.

SZA, bipolar type.



#6 LexFlex



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Posted 12 July 2012 - 07:33 PM

Well if I miss a dose my thinking is fine but by like the third missed one my thinking, feelings, emotions start effecting me negatively. Thats what I meant by 'I'm afraid my thinking will change'. I hope it didn't imply anything else. Now Seroquel when I was on it, I couldn't miss a dose because if I did, I'd know that same night by not being able to sleep. What works for me for sleep and its a good one is, 4 melatonin and 1 diphenhydramine sleep aid. I had my best consecutive restful nights sleep until last night, I drank just a large coffee in the morning and it altered my sleeping pattern. But anyway, I agree some meds you don't notice hardly anything if just one dose is missed but like you say, if its several then that may be something to be concerned about.

#7 Revan



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Posted 12 July 2012 - 08:28 PM

If I miss a dose of risperdal I feel a bit edgy the next day. However, after resuming it I feel normal within a few hours. I can take double the amount the next day if I miss a day but I try not to do this too often. It's best too keep the dose fairly constant for me. Sometimes spacing out my APs twice or three times daily is necessary. With risperdal I take a lower dose in the morning and a higher dose at night because it makes me sleepy and apathetic if I take too much during the daytime.



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#8 Cetkat


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Posted 12 July 2012 - 08:43 PM

With the Seroquel - that impacts sleep because it can be a sedative. So, yes, missing a single night will hinder your ability to sleep.

That's different from the half-life time period (where afterwards you will experience withdrawal symptoms) - as well as the anti-psychotic properties that may take longer to wear off because it takes longer to produce the effect.

Half-life is very med specific and cannot really be generalized.

Mostly, my opinion would be that unless the half-life is rather short, missing one dose would not affect the ability for it to keep away psychosis so long as you take the next dose.

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Dx: Major Depression w/ Dysthymia, Panic Disorder, GAD, ADHD, Fibromyalgia
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#9 gizmo


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Posted 13 July 2012 - 04:00 PM

I generally can go three days (which I only do if im actively vomiting for that long) without feeling any effects from not taking my meds. If I happen to forget a dose, I do not take it in the morning, but just wait and take my next regularly scheduled dose.
Diagnosis: BP I with Psychotic Features, GAD, ADHD, Chronic Migraines, various physical stuff.
Meds Currently On: Depakote 2000 mg, Risperdal 8 mg, Latuda 80 mg, Prozac 60 mg, Vyvanse 70 mg, Propranolol 40 mg BID, Klonopin 2 mg BID PRN
Meds Sort-Of Mental Related: Lipitor 40 mg, Zofran 4 mg PRN, Fioricet PRN, Stadol PRN, Botox received on 8/16/13

I post on an iPhone, so please forgive grammatical errors or strange word inclusions. It's the auto correct!

#10 hallowedink


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Posted 13 July 2012 - 04:14 PM

I've gone a maximum of two days without taking a med (e.g. when I don't get refills in time), but each time it was only one single med at a time. Once I forgot to take a dose of Seroquel in the evening, so I took it the next morning. I can't actually remember anything about that day, except that I felt awful - groggy, completely out of it... I haven't forgotten to take a dose since then.

My Brain Salad: BPD, MDD, Insomnia, Anorexia Nervosa, "very likely" C-PTSD, Migraines
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#11 g8orgirl



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Posted 13 July 2012 - 04:58 PM

If I miss a dose of Seroquel I notice it for sure because I cannot sleep without it. With the Risperdal if I go more than about 3 days, I notice my psychotic symptoms coming back. I've always been affected by meds very quickly. Whenever I've switched to a new antipsychotic, I usually notice a significant reduction in my symptoms within a few days as opposed to the several weeks that it's supposed to take.
Schizoaffective - depressive type
Meds: Abilify 5 mgs, Effexor 75 mgs, Trazodone 100 mgs

#12 Titania



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Posted 14 July 2012 - 09:36 AM

The point is that it is very individal how people will experience the effects of a medication, so it's impossible to tell from a straw poll how long it's safe to leave it until retaking your dose. I know this is just a hypothetical discussion on peoples experiences, but it's worth pointing out.

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#13 LexFlex



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Posted 14 July 2012 - 08:29 PM

Yes, very individual because we don't all take the same AP's. And no two bodies are the same. I just wondered how people felt in general if they miss a dose, then the next day go back to their same regimen. I wondered if there was any noticeable fluctuation that a person could feel in their bodies due to just one missed dose.

#14 ghostrx



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Posted 24 July 2012 - 12:58 PM

Used to feel a bit 'strange' (was only on it for a few months) but now I can go two days without it and feel fine, although I can't sleep when I'm off it (either ran out or can't get down to fill it on the day).

Rx: 300mg Ranitidine (2x150mg), 45mg Mirtazapine, 25mg x 4 Thorazine, 100mg Thorazine, 50mg Promethazine
Past Rx: Prozac, Citalopram, Paroxetine, Sertraline, Effexor, Cymbalta, Ambien, Temazepam, Valium, Omeprazole, Valdoxan, Zopiclone, Seroquel

#15 konings



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Posted 25 July 2012 - 07:39 PM

It affects me pretty badly. When I dont take seroquel in time the positive symptoms start to return fast. When I didnt take risperidone my senses sharpened and i became very irritable. All this within 3-4 hours after not having taken meds.

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