Blood test for depression? Thoughts?
#1
Posted 01 February 2013 - 12:57 PM
Rx: 225 mg venlafaxine HCL (currently titrating up to 300 mg), 900 mg gabapentin AM, 900 mg gabapentin PM, 50 mg trazodone
past Rx: Paxil, Wellbutrin, Lexapro, clonazepam, lorazepam
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#2
Posted 01 February 2013 - 01:00 PM
I can see this being a research tool to help us understand endophenotypes of depression and predictors of treatmet response. But I can't see this being a good idea at point of care unless it can be proven that it is extremely sensitive.
Edited by tryp, 01 February 2013 - 01:08 PM.
Dx: C-PTSD, MDD, BPD
Rx: Lamictal (250) Seroquel (200/tapering) prazosin (7) + DBT + Supportive Psychotherapy
#3
Posted 01 February 2013 - 01:08 PM
I think it's interesting. I wonder what else is going to come out? But, I wouldn't pay for it out-of-pocket if it isn't covered by insurance.
schizoaffective bipolar type
abilify, lamictal, lexapro, wellbutrin
#4
Posted 01 February 2013 - 01:33 PM
Well, my last thought is the cost. I fully admit I have no idea how much a blood test for lithium costs, or a blood test for thyroid stuff costs. These are fairly "regular" tests that insurance companies pay for. But if i was queen of insurance I don't know if I would pay for this depression test.
I've read other articles about the prospects of a blood test for MI and I may have posted them. I like the idea but its the correct answer rate (for lack of better scientific term) that concerns me for a blood screening for depression, MI, etc.
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#5
Posted 01 February 2013 - 03:00 PM
I think this is an incredible breakthrough! Medicine is finally coming out with tests for mental illnesses. It could be devastating but if the person is self-harming, suicidal or otherwise not functioning I doubt a decent physician would suggest it's not real. Plus if a blood test told me I wasn't depressed maybe it would cause a placebo effect. I don't know, this raises a lot of questions but I'm optimistic about it!
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#6
Posted 01 February 2013 - 03:07 PM
Sure, it would feel good for people who tested positive, but what about the negatives?
In physical illnesses, a screening test is followed by further imaging and confirmation. There is nothing further to verify the results of this test or catch individuals who are missed.
Dx: C-PTSD, MDD, BPD
Rx: Lamictal (250) Seroquel (200/tapering) prazosin (7) + DBT + Supportive Psychotherapy
#7
Posted 01 February 2013 - 03:11 PM
I think it might be easier to accept a dx if you have a test and data. I would think the competent physician would still take a history to verify the results.
schizoaffective bipolar type
abilify, lamictal, lexapro, wellbutrin
#8
Posted 01 February 2013 - 03:12 PM
Dx: C-PTSD, MDD, BPD
Rx: Lamictal (250) Seroquel (200/tapering) prazosin (7) + DBT + Supportive Psychotherapy
#9
Posted 01 February 2013 - 03:17 PM
I just think it's exciting that they are starting to come out with tests. If you could differentiate bipolar and schizophrenia or major depression from bipolar that would be helpful. And, I'm waiting for one that will predict which meds will work best.
(I know this test doesn't do any of that, just thinking)
schizoaffective bipolar type
abilify, lamictal, lexapro, wellbutrin
#10
Posted 01 February 2013 - 03:19 PM
I can just foresee a test like this being used to replace a comprehensive assessment by a psychiatrist, leading to incorrect treatment.
I have always been taught "Don't order a test unless it will change your management of the patient."
Edited by tryp, 01 February 2013 - 03:24 PM.
Dx: C-PTSD, MDD, BPD
Rx: Lamictal (250) Seroquel (200/tapering) prazosin (7) + DBT + Supportive Psychotherapy
#11
Posted 01 February 2013 - 03:41 PM
For example how many wipe BP who seek treatment during a depressive episode would get this blood test and if they did would they test positive? If not then would they be turned away and told there is nothing wrong with them? And if they test positive, got diagnosed with MDD and put on an SSRI, we know the damage that can cause and tons of people could be sent into destructive mania.
I think releasing this might be premature. They're is too much of a spectrum and too many overlapping symptoms in MI but if they could come with more test or a test that explores other possibilities than just one diagnosis than it. would be awesome.
Ofcourse if someone had been going too a pdoc for a while and pdoc was already pretty sure it was MDD then gives a blood test just too further prove the diagnosis that would be great too
It definitly has potential too destigmatize MI but should not replace pyschological evaluations
Dx BP I Rapid Cycling, GAD, Social Phobia, Panic Disorder,PCOS
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#12
Posted 01 February 2013 - 03:42 PM
I wonder how this would work with depression that is situational, rather than purely chemical. Would it be able to identify "oh, you're grieving, and that's why you're sad" without a history being taken? I doubt it.
I did manage to get dx'd with depression once: they didn't do a good screening job and we were being abused at the time, as well as abusing drugs to cope with the abuse. Because they were never told about the abuse the symptoms seemed similar enough, I guess. I wonder what a test would have said; I doubt that it, too, would have noticed that pain that we were actually in.
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#13
Posted 01 February 2013 - 03:45 PM
Dx BP I Rapid Cycling, GAD, Social Phobia, Panic Disorder,PCOS
Rx lamictal 300mg, Busprone 60mg, cymbalta 30mg, Abilify 5mg, Metformin 2000mg
previous Rx zoloft, prozac, lexapro, geodon, seraquel, depakote, xannax, ambien, trazadone
Mental Illness is a flaw in chemistry not character.
#14
Posted 01 February 2013 - 03:55 PM
The MDDScore test is expected to cost $745.
Dx: Major Depressive Disorder, Attention Deficit Disorder PI, Refractory Insomnia, CSA, Temporal Lobe Epilepsy, Dyspraxia, Tremor
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#15
Posted 01 February 2013 - 04:30 PM
I think that money could better spent on working on other areas of mental health treatment.
The blood test seems kind of unnecessary, like the only point of it is to try prove that depression is a 'real' illness, and those of us who are depressed already know that. ![]()
It'd be interesting to see how accurate this would be though.
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#16
Posted 01 February 2013 - 05:32 PM
I wouldn't want it solely to diagnose depression, but maybe as an adjunct to other factors.
Current Psychiatric Dxs ... Schizoaffective, bipolar type; Anxiety disorder, PTSD, agoraphobia
Also recovered Anorexic/Bulimic finally after 20 years.
Current meds: Provigil, Klonopin, Naltrexone, Wellbutrin, Abilify, Lamictal, Prozac, Lansoprazole (Rx strength), Linzess, Flonase, Methimazole, QVAR inhaler, Xopenex inhaler, Xanax, atenolol.
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#17
Posted 01 February 2013 - 05:41 PM
The MDDScore test is expected to cost $745.
Psh. Yeah, okay.
I don't need to spend $745 to figure out that I feel like ass. I already KNOW that, and so does my doctor. I mean, the people who are going to pay for these tests, well, they already know something is wrong with them, right? So why don't they go see a person to diagnose them? It's cheaper. I find it interesting that it's possible to tell whether or not someone suffers from depression with a blood test, but I have no idea why this would be necessary. "He fits the DSM criteria for depression, but I think he's lying! Let's submit him to a blood test!"
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#18
Posted 01 February 2013 - 05:51 PM
If it werent for alll the concerns though I would love too take the results and shove it in alll the peoples faces who tell me too just get over it.
Something needs too happen too destigmitize.
Also I wonder how this test might eventually be used too determine dissability eligibility
Dx BP I Rapid Cycling, GAD, Social Phobia, Panic Disorder,PCOS
Rx lamictal 300mg, Busprone 60mg, cymbalta 30mg, Abilify 5mg, Metformin 2000mg
previous Rx zoloft, prozac, lexapro, geodon, seraquel, depakote, xannax, ambien, trazadone
Mental Illness is a flaw in chemistry not character.
#20
Posted 02 February 2013 - 10:21 PM
There seems to be too many variables when looking at depression in general, let alone a blood test.
Current Psychiatric Dxs ... Schizoaffective, bipolar type; Anxiety disorder, PTSD, agoraphobia
Also recovered Anorexic/Bulimic finally after 20 years.
Current meds: Provigil, Klonopin, Naltrexone, Wellbutrin, Abilify, Lamictal, Prozac, Lansoprazole (Rx strength), Linzess, Flonase, Methimazole, QVAR inhaler, Xopenex inhaler, Xanax, atenolol.
Any questions just ask ![]()
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