D, on Jan 12 2009, 09:10 PM, said:
My, that was a bit off the point. Yeah, I've mixed it. With alcohol, the hangovers sucked badly while on my way up to 200 mg/day. After taking it for a couple years, the massive hangover effect has slightly diminished (still worse I think). Also, hangovers don't seem to be as bad the second day if you ended up going out and drinking both nights on a weekend.
I wouldn't drink on it unless you are already climatized to the medication and feeling decent and stable. Obviously, it depends on how much you drink as well. I'm speaking more from the perspective of people drink to get drunk (or end up drunk sometimes). Even my psychiatrist says you can have 1-2 drinks on it occasionally if you aren't using it for epilepsy. Under those circumstances, the effects aren't too noticeable for me.
Reply: My boyfriend of two years is on 200mg of lamictal for bi-polar disorder. He takes it at 9:00 am every day. He eats breakfast at 11:00 am every day. He leaves for work at 1:23 pm every day. He starts work at 2:00 pm every day. He is loving and kind and thoughtful and works very hard to control his anger and unreasonable responses to "normal" stress (having to wait in line at jack in the box used to send him into a rage of yelling and beating the steering wheel and basically LOSING IT). I have noticed a HUGE improvement in his overall happiness. THEN HE STARTED SMOKING WEED....

he detached from our relationship slowly but surely, he started getting annoyed by everything and anything, being very distant and void, and after about 6 mos started major depression, having crying fits, bursts of rage over the tiniest thing (not returning a movie to blockbuster a day early for him would induce punching-a-hole in-the-wall anger). He was a complete stranger and I had to leave him for a month before he realized what was happening and quit for good. He hasn't touched weed since. I have noticed a HUGE improvement and he thanks me every day. We went through the same thing with alcohol. He is so fun and charismatic and we would have a great time drinking, a glass of wine with sunset or saki bombs at the local sushi restaraunt. I was very unfamiliar with bi-polar and meds for it before all this. I began doing research when he started getting really moody and when we would wake up, i would be fine and he would be so depressed. It was like he wasn't taking the medication at all. I actually sat him down and asked him if he was taking his meds or if he had gone off them and was hiding. He listened to me as i asked him " when was the last day you didn't struggle all day?". He realized that he had been struggling so hardcore and it was largely due to the alcohol. After 2 weeks of not drinking he was a whole new man. we used to have a blast getting buzzed and dancing and being silly but nothing could be more rewarding for me than seeing him wake up feeling good and being able to sleep 8 hours at night and making love to me and having more good days than bad days. there are still bad days but he/we is/are able to get through them in one piece now.
After doing research I learned that alcohol can basically counteract or subtract the affect/benefit of lamictal and increase the symptoms of bi-polar. Also, since scientists don't actually know exactly how lamictal works, it doesn't surprise me that so many people have such a varied reaction. You may think it isn't affecting you but you may want to sit a partner or a loved one down and ask them to be honest with you. He didn't even realize how much more miserable he had become until it was right in his face.
All said and done, his quality of life, happiness, success at work and in friendships, health, self esteem, our relationship, is SO much better sans alcohol and rec. drugs. We find highs in life (i know it sounds so corny) but ziplining, rafting, salsa dancing, naked hide and go seek..... there a million more rewarding things to do than jepordize your life and relationships.