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mikl_pls

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About mikl_pls

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  • Birthday 09/11/1987

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    Alabama, US

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  1. I looked in the US FDA National Drug Code Directory for authorized generics of clonazepam, which means it would basically be just like brand name, but unfortunately, out of all the generic manufacturers, there are no authorized generic manufacturers. I was gonna rely on that being my input, but that fell through the bottom. I'm sorry. I hope your situation gets resolved ASAP.
  2. I understand. They can be pretty tricky. I had to take a class in 7th grade to learn how to use Office, so I guess that's how I got started with them.
  3. But... but... Why nooooot? They have such potential to be a great friend for you! They're so handy and helpful! (This is coming from someone who's a spreadsheet addict though, so take that with a grain of salt... I'm also just kidding...)
  4. I use two Android apps to track my current meds that I'm taking and to remind me to take them regularly: Medisafe (also on iPhone), and Med Helper (I believe it's on iPhone as well). Also, my mood tracking app, eMoods, helps keep track of taking meds. As for what meds I've taken, I used to use Word, but now use Google Docs (either are pretty much the same, just one syncs with your Gmail account so you can access it anywhere like with your smartphone). I have a document that lists my current medications, dose, directions, what it treats, and prescriber. Then I list my surgeries, OTC supplements, etc. Then below all that on a separate page(s), I list all the meds I have taken. If you want, I can send you a copy of it in a message as an example. It's really handy to keep up with all the meds you've taken in the past.
  5. I didn't have any good luck with Pristiq. I was on 50 mg and it did nothing. Went up to 100 mg and I still felt very weepy and dysphoric. I switched back to Cymbalta at the time, which I was on prior to Pristiq the first time and immediately felt better, but put myself on a higher dose than I was on previously, 90 mg Cymbalta, because my pdoc refused to go above 60 mg (max is 120 mg). My pdoc finally agreed to give me 90 mg Cymbalta then. Then when Pristiq went generic, I asked my gdoc if he would give me higher than the max dose, since he actually does PAs (my pdoc literally has no time to do PAs), and he agreed to put me on 150 mg. Not surprisingly, it did nothing. I wanted to try even higher, but my pdoc said 150 mg was too much, which I disagreed with. So I had to switch to something else. They actually studied up to 400 mg in the clinical trials. But as @CeremonyNewOrder said, no additional benefit was shown above 50 mg. The 100 mg dose is kinda a "just for the hell of it" dose I think. Some people actually do get benefit out of going above the max dose. I've read of people taking 300-400 mg Pristiq and getting benefit from it, but at the same time, I've heard of some taking that much and it being a nightmare.
  6. I'm so happy to hear this! You have a lot of room to go up on the glycopyrrolate if you need to. But if you do, you might have stuff like not sweating enough which could lead to overheating in hot weather and stuff like that, plus blurry vision, etc., etc. (other anticholinergic symptoms) I wish you continued good luck!
  7. I think the only experience I've had with brand vs. generic like this has been with Effexor. My best friend had a bunch of brand-name left over that he got directly from the pharmaceutical company after he quit taking it that he gave me when I started it. I started on brand-name and then switched to generic and it was like day and night. Other than that, I haven't had any experiences. I mean, I took brand-name Pristiq and generic Pristiq too, but neither of them worked for me at all anyway. My pdoc said that when Cymbalta went generic, many of her patients had a lot of problems with it. If you go here, https://www.accessdata.fda.gov/scripts/cder/ndc/index.cfm, and select "proprietary name," and type in the generic name of the drug, then it will come up with all FDA approved generics. Then what you will need to search for on the next screen is "authorized" in the search bar on the top right. If anything shows up under the "Market Category" as "NDA AUTHORIZED GENERIC," then that will be as close to brand-name as you can get with a generic. For generic Cymbalta, there appears to be only one manufacturer, "Carilion Materials Management," and it's only the 60 mg capsule. You will need to copy the NDC Package code (for this product, 68151-4727-3) But it appears it's only 1 capsule in the package for some reason... so... I guess never mind on that... otherwise you could bring that information to your pharmacy and request that they order from that manufacturer.
  8. Lithium made me more depressed too, in addition to causing seizures.
  9. You may actually need a higher dose of Cymbalta. Cymbalta 60 mg worked for me for a few months, then I felt like I needed a higher dose, which my pdoc denied me until I put myself on a higher dose of 90 mg, which she then agreed to put me on. The max dose is 120 mg. But you gotta give it a chance at the initial dose for it to take effect so you have somewhere to go later on if you really need to increase it, if that makes any sense.
  10. What dosage of the glycopyrrolate did she prescribe you and how often can you take it? As an antisialogogue (to prevent salivation), it can be taken 1-2 mg 2-3 times per day up to a max of 8 mg/day according to Epocrates.
  11. It has been said that Fanapt can be useful for those with PTSD itself because of its affinity for the α1 receptor. So theoretically you could probably replace the prazosin with Fanapt. I don't know exactly how the binding affinity compares for Fanapt vs. prazosin for the α1 receptor. But here's an article about using Fanapt for PTSD. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140622/ I hope that gives some insight into using Fanapt. There are also a few other SGAs you haven't tried, I believe, by looking at your OP and your signature: clozapine (last resort, of course... Has pretty potent α1A antagonism anyway...), Rexulti (has potent α1B antagonism, even more potent than Fanapt's α1 antagonism, so might interact with prazosin...), Saphris (has potent α1 antagonism, so might interact with prazosin), and Vraylar (not much α1 antagonism really to speak of...).
  12. If you're taking prazosin, you may have to stop taking it if you start taking Fanpat because they are both potent α1 adrenergic antagonists. Also, the up-titration for Fanapt is kinda slow if I remember correctly. (I've not taken it before, I just remember reading about it.)
  13. My pdoc says the same thing about me sometimes. I tell her that I haven't been doing well lately at all, and she responds with, "well you're looking good!" It feels very invalidating sometimes, but I think I see what she's saying. She has insight that I don't. There's the me that I see, and there's the me that she sees. But then again, there's also the me that my family and friends see that she doesn't see, so sometimes I have to bring them with me into my sessions to make a point about just how badly I'm doing sometimes if she's not quite getting the point. But apparently I'm doing well here lately as she has left my cocktail alone more or less for the last three months or so. But I don't feel like I've been doing that well off. But I think it's good that she's done that, because there have been times in the last three months when I wanted her to alter my meds because I felt horrible (depressed or manic), but she thought I was doing fine, so she only altered it a little or left it mostly alone so as to keep me stable. Stability is paramount. This may or may not be the case for you, though. I just thought I'd mention that. But I do confess that I have purposely not showered and shown up in sweat pants and a dirty shirt and messy hair just to show her how shitty I feel. I have taken to making almost "chatty" notes for myself, like, verbatim notes as to exactly what I want to say to her and how I want to say it so I won't forget, because when I'm in the moment at my appointment, I tend to get flustered and overwhelmed with my thoughts, and I will forget something. Even then, I forget stuff, and often times have to skip over stuff because my notes are too long. If you feel you aren't doing well and you really need to see your pdoc, there's nothing wrong with calling in and getting an appointment with your pdoc to see her in between appointments. I hope you get to feeling better!
  14. Here is a link to your other thread that you mentioned in your OP in case anyone wants to refer to it. I'm not very sure if this could be the cause of your symptoms, but since Abilify is a dopamine partial agonist, you could be experiencing dopamine agonist withdrawal syndrome (DAWS). https://www.ncbi.nlm.nih.gov/pubmed/23686524
  15. She might have mentioned glycopyrrolate, as glimepiride is indeed a diabetes drug. Glycopyrrolate is an anticholinergic drug like benztropine (which is as you said Cogentin) that can be used for sialorrhea (I believe both are mentioned in the article). WHY WOULD SHE WANT TO WAIT?! I would call like, the next day and be like, "yeah, it's worse, she said to call if it's worse, gimme one of those meds..." lol. Omg, I so understand phone anxiety, I haaaate making phone calls about certain things. I do believe the second "g" medicine is glycopyrrolate. Brand names are Robinul (1 mg tab) and Robiul Forte (2 mg tab). If you just call it "Robinul" then they will know what you're talking about most likely. I'm not sure which is a more potent anticholinergic, but I know that Cogentin is a very potent anticholinergic, and if you take it more than a few days at a time regularly, you will get an insatiably dry mouth (that you can't get rid of by drinking water), blurry up-close vision (you will have to get reading glasses), possibly urinary retention, and, in my case, possibly hallucinations and delirium set in after about 2-3 weeks of taking it. I was taking it for hyperhidrosis, and good lord at the side effects! I don't see how people take this medicine regularly, especially older patients who take it for Parkinson's disease, who are more susceptible to anticholinergic side effects and who are on higher doses! Just a little warning about the side effects of Cogentin. I think Robinul (glycopyrrolate) is peripherally selective, meaning that it doesn't act on the central nervous system, but don't quote me on that! That means that you wouldn't get the hallucinations and delirium, or there would be less likely of a chance to get that anyway... But still, don't quote me on that. I think your pdoc would be the one to make the decision as to which medicine you should take for the sialorrhea (excess drooling). EDIT: Just checked and yes, glycopyrrolate (Robinul) has "a very limited effect" the CNS.
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