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bipolarsara posted a topic in Antidepressants - If You're Crappy and You Know ItI am on 300 my of effexor xr and have been for several months. Prior to a breakdown, I'd previously been on between 75 and 150mg for maintenance and found I had almost no side effects (except for the terrible brain zaps when I'd miss a dose). Current meds are 300mg effexor, 50mg lamictal and 50 mg seroquel. Over time I'd like to decrease the effexor back to a level where side effects were minimal. First my doctor wants to titrate up on lamictal. My primary complaints are brain fog and sexual side effects. I know that these are not as serious as other side effects but they really do impede on my general enjoyment of life.. Basically I am hoping to hear from other people who have had experience with effexor at various doses and what their experiences with various side effects were. Thanks in advance for any replies.