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Found 48 results

  1. I have been titrating lamictal, was at 25 for 2 weeks, and just started 50 today. I have been having increasingly worse sleep, and the past few nights couldn't sleep without taking klonipin, and still woke in the middle of the night. My question is could this be a temporary side effect that goes away once I am on a therapeutic dose for awhile? I have called my pdoc to see if they can subscribe something to help me sleep. I also take zyprexa (which usually helps sleep but not anymore) and gabapentin. Very stressed out bc I really want lamictal to work for my bipolar depression, and so far no other side effects. I feel like my mood is already better and things are going well except for the sleep issue. Thanks for any input!
  2. My psych doc has called two times to see if I started on the Latuda. I haven't. I originally wanted to wait until the Seroquel and Pamelor left my system before I started anything new. That was 3 weeks ago. Now experiencing inking in of paranoia, insomnia, fear, anxiety, depression, more migraine and it's preventing me from starting Latuda. I have some key appointments I have to keep between now and the end of the month that I absolutely cannot cancel. I don't want to start Latuda and experience overwhelming side effects that will scare me from leaving my home to make these appointments. However, living in agony with these symptoms is horrible and I know I need to start on the Latuda. After todays appointment, I will have 10 business days until my next appointment, I could take a small sample and see how I react for a few days. I'm also still spending like crazy, have maxed out all my credit cards, applied for more. I know I am doing this to comfort myself. However, I am now sending back more than half what I am buying, but I am in trouble with one credit card. I called my bank and asked for help and they agreed to suspend my credit card until I get it under the credit limit. All this spending started after I watched my neighbor pass away and since then I have not been doing my daily walk because the only path I can use with my rollator is right where she passed away. I just haven't been able to get myself beyond this. I tried starting with a trauma therapist but that ended badly, she wanted me to discuss my past traumas in detail during the first and second meeting and half way thru the second meeting I flew out of her room having a panic attack. I kept warning her I needed to work on grounding and she wouldn't, so won't go back. She hasn't called to see why I haven't been back, so will let that one go. I'm a basket case right now.
  3. This is what I go thru every day from the moment I wake up: anxiety throughout the day, uncontrollable anxiety and panic only when I leave my home, dissociation in times of high stress and high anxiety and panic, insomnia every night, daily depression, scary cycling mood swings. My psych doc called me on a Saturday afternoon (now this doc is semi-retired and only works 3 days a week now). I was shocked when I saw his name come up on caller ID. He was calling to suggest I go into the hospital until I become stabilized. Stabilized in one week, no way I say. It's gonna take time for that to happen. He said with the dissociation and everything else I am going thru on a daily basis he is worried I might self harm. I assured him I am not at that point and he knows that I call him when I need to go back in, plus I have a new kitten and don't want anyone in my home anyway. I think I can manage all this at home. I will be seeing him on Tuesday. That was soo out of character for him to call me like that, kinda got my attention and am I worse off then I realize. I have known him for 30+ years and he knows me well, so I have to trust his direction. His concern is that I am in the middle of a perfect storm and anything can happen and he worries that if anything triggers me I might not be able to control what happens to me. Then several neighbors stopped by to see if I was okay as they have not seen me last week, curtains have remained closed, not answering phones nor texts. I know I have been avoiding alot of neighbors now as I am selectively avoiding those that trigger me and those that knocked on my door I call them "the axis of terror" for what they have been known to do to other people here. So, I had their phones on block. I have been protecting myself while I work on medication and mood and it's nobody's business. Had a game of RummyKub set up for this evening and really looked forward to this all week, and everyone just canceled, really bummed about that. I have had no interest in bath, washing my hair, eating. I can't focus on TV, can't read, nor listen to my book tapes. No interest in anything, I am soo flooded with anxiety/panic. My HMO has restricted how many benzos I take, I have been on Klonopin for 30 years and that takes the edge off, but have to stock pile them due to the restrictions and delays in getting the medication to me, so had to cut back and that makes my anxiety worse. So, back to my psych doc. The plan is to keep me on Seroquel (1/2 of a 25 mg) at night for sleep and for mood control for now during the day until I see him next week. It just sedates me too much if I take more than 1/2 of 25 mg in a 24 hour period. But the Seroquel puts the breaks on mood cycling, I just can't tolerate the side effects, they never go away, just increase. So, I am going to suggest to him for sleep (I want to get off Seroquel due to over sedation and muscle rigidity), Ambien or Trazodone. I read up that Trazodone helps with insomnia, panic, migraine. Then I need a mood stabilizer/seizure medication so may go back on Depakote and Xanax for rescue from intense anxiety/panic. I don't want to go back on Lithium. Goal for the day, making my bed and taking a bath, maybe washing my hair.
  4. Anyone here have any recommendations for a soft soothing "pink noise" machine? someone mentioned this the other day, and i wasn't sure the difference between pink vs white noise (maybe just marketing ploy). I need something to block out very subtle electrical-type noises (noises that seem loud at night - like the whirring of a refrigerator, or a neighbors appliance, for example. But some white noise machines (like at therapist offices) are too loud. Ear plugs are not comfortable for me, or they fall out of my ears when sleeping.
  5. I want to try Nortriptyline again, but my psych doc is hesitant. He prescribed me Seroquel and Abilify but my pharmacist refused to fill them, advising not to take them together at my age (67). I used to take Pamelor for 30 years and where it did nothing for depression, it controlled anxiety, panic disorders and managed migraine. Waiting to hear back from my psych doc today if he will approve Nortriptyline. I need to sleep. I need something to help with agoraphobia, terrible anxiety and panic. Everything I take activates anxiety and panic. Leaving my home is a battle with fear. Thank you.
  6. Just got a phone call from my pharmacist. She will not fill the Seroquel and Abilify together due to the black box warning about prolonged QT interval causing sudden death. Any of these class of medications, she is urging that I have an EEG to see how my heart is doing before starting any of them. I am 67. I need to be able to sleep and insomnia is a big player in my life. Seroquel helps me sleep, but pharmacist does not want me to mix Seroquel with anything else in any category. So, will stop the Seroquel tonight, only have been on this for 3 days, so I shouldn't have any adverse effects. I do have GAD and panic disorder with insomnia. She did fill Abilify for me, but that is activating (prior experience). I need something to counterbalance the anxiety it provokes and the insomnia. I asked her to check Pamelor, a trycyclic antidepressant and it is not recommended for anyone over 65, only due to sedation issues. I was on Pamelor for 30 years about 10 years ago and went off of it due to having interactions with other medications. I tried to go back on it this year while on Zonegran but it interacted with that medication. I am now off of Zonegran due to a kidney stone. I do feel that Pamelor is the best for my GAD and does aid with sleep. Now that I am a senior trying to take medication I am finding all these obstacles. Reaching out to this community to see if anyone has any suggestions or had experience combining Seroquel an d Abilify. Thanks
  7. Hello again.

    Hello again friends. It has been a few years. I was HaloGirl66. Or IndyMode. I can't remember. But I re-registered because I couldn't recover my old user info. I've had severe insomnia, ADHD, GAD & Migraines for years and am now going through a bipolar diagnosis. So hello again. -Mandy
  8. I am 22 y/o and have filed for SSI twice. The first time I got denied I didn't appeal within 60 days so I had to apply all over again. Now I am going through to extensive appeal process and no lawyer seems to want to help me. They claim since I am young, I almost need to have schizophrenia or an autistic/spectrum disorder to be able to actually be approved and get benefits otherwise it is going to be very hard to get SSI. Now here are some of the facts of my case. I was fired from my job last November due to "no call, no show" because I was in a bipolar depressive episode where I literally didn't leave my room but maybe 5x to make a microwave meal and shower once. This episode lasted a little bit shy of 2 weeks. So for my 3 no call, no shows I was terminated from my job at University. I asked if they would accept a physician's note explaining my circumstances but the manager actually refused documentation, saying "No it's not necessary, I don't need that". She also said that I should have called and at least have told her what was going on so she knew I couldn't come in, but let's be real guys, doing that during a severe bipolar depressive episode is like writing a PhD dissertation in less than a day. So I applied for unemployment and get a denial letter saying I am denied benefits of $50/week because they contacted my former employer and was told I was terminated for misconduct. So that was the end of that. I had applied for SSI last year around August I would say and was denied 1st time. Re-applied December and got denial letter again, this time on Feb. 8th stating "your conditions are not severe enough for you not to work. You are capable of substantial gainful activity". Yet on my listed disabilities I listed epilepsy (reoccurring grand-mal seizures), bipolar disorder NOS, insomnia NOS, ADHD, generalized anxiety disorder, panic attacks, manic episodes, social anxiety disorder, delayed sleep phase syndrome, and listed all the medications I was on and how some of them has side effects that were impairing themselves. Has anyone here who is young actually gotten approved for SSI benefits? If so, how many times did it take for you to finally get approved and did you use a lawyer to help you through the process? Also, if you don't mind, what conditions/disabilities did you report to them that you believed qualified you for SSI or SSDI? I can't apply for SSDI because I don't have enough work credits so I can only apply for SSI. This whole process kinda sucks and is difficult especially for people with disabilities. So frustrating.
  9. I realize that I have been having a bad physical reaction to remeron since I started taking it near the end of November. I am currently taking 7.5 mg, cutting down from 15 mg two weeks ago. I was wondering if anyone had stopped taking remeron after being on a 7.5 mg dose or do you need to break that in half? I was also wondering if anyone had gone from remeron to seroquel? I am already having a hard time sleeping and was thinking about going back to my old 50 mg seroquel dose at night instead of the remeron. I will see nurse practitioner on Monday but wanted to hear experiences from other people.
  10. So I have been on xanax 1mg two to three times daily for about 1-1.5 years now; Paxil is great and I don't need xanax when on paxil but it makes me manic as hell so that isn't really an option. Been thinking whether Zoloft would be any different.... Anyway, still on xanax same dosage, but just doubled my valium from 10mg at night to 20mg at night because I was waking up from sleep with difficulty breathing and panic symptoms. I asked to try ativan, eliminate the antipsychotic i use for sleep mainly since ativan 2mg really helps with insomnia, and get rid of the valium. Well she said lets try increasing the valium first then we will go from there. Valium honestly does nothing for me. At 10mg I legit feel nothing. It takes at least 40-60mg for minimal anxiety relief. I respect its long half-life but if it's not benefiting much for sleep, or other anxiety problems in the morning I feel like why should I continue it. Switching to ativan 2mg at bedtime could get me off valium and saphris for sleep (would love to not be on an antipsychotic mainly for sleep anyway). Ativan very little to no next day drowsiness, cognitive impairment, lethargy, flat mood. Refreshing sleep is what ativan gives me. Any ideas why the dr might be pushing for valium instead even after I explained it doesn't help for sleep, for anxiety, only thing it is good for is if i dont take my xanax for 1-2 weeks and I wont have a seizure, but my neurologist said lamital should cover that since it's an anticonvulsant. I don't know whether to stay on 2 benzos as the same time, whether it's xanax and valium or xanax and ativan, or to ask for an increase in xanax to maybe 5-6mg/day in divided doses, maybe 2mg twice per day and 1mg once per day, or 2mg 3x a day. My neurologist said if you need to be on these types of medications than it is warranted and pretty much OK in my case. Klonopin sucks, not as much as valium, but it does barely anything for anxiety, esp. panic, or sleep. Makes me have a depressed mood actually, while xanax uplifts my mood and helps me enjoy life without having anxious mood and panic attack symptoms. Ativan just makes me drowsy so I prefer that for sleep. My main question is regarding how i could proceed. Adding ativan, stopping valium maybe saphris, or upping xanax dose and being on only one benzodiazepine. I do have a tolerance so higher doses than 1mg sometimes are needed to stop anticipatory anxiety, avoidance anxiety, and esp. panic attacks. Restoril doesn't help with sleep surprisingly. Never tried triazolam but would love to due to its short half-life and potency/efficacy for insomnia, but my dr thinks it wouldn't be a good idea. Dr says stims may be increasing my anxiety but don't think that is the case. Really want an effective benzo combo or pick to be on xanax only, just at a higher dose. My parents think its crazy to take 3 xanax a day but it's what helps and lets me live life. Somtimes i take more than prescribed because 1mg will not help my symptoms. I just want to be on a stable dose, whether its xanax 3mg xr 1x daily with 1mg 3x daily or 2mg 3x daily. Something has got to give, and the hardest part is even bringing up increasing my xanax dose with my dr because of its bad reputation since everyone seems to abuse it nowadays. I'm ready to take a trip to mexico and take a visit to their pharmacies...
  11. 8 Days

    My girlfriend has gone as much as 8 days without sleep. The hospital she stayed at finally had to give her propofol to put her down. Is this normal?
  12. So I am in quite a nasty situation. Over 3 months ago I was able to kick my addiction to heroin with therapy and Suboxone. Also, I successfully got my bipolar II under control with Lithium ER 900mg and Seroquel XR 300mg. For the last 6 weeks I am having fragmented sleep. I am able to fall asleep relatively easily only to wakeup after 2hrs. I then go back to sleep and from then on I wake up roughly 5 times a night. I've eliminated all caffeine from diet, I don't smoke cigarettes within 2hrs of bed and I don't watch TV or use any other screen before retiring. My addiction specialist has tried me on trazadone 150mg--did nothing Doxepin 75-150mg--only makes me sleeoy Ambien CR (w/ doxepin)--barely any change. I think it slightly improves the quality of sleep in between waking up. Does anyone have any recommendations for a sleep maintenance medication? I prone to rapid weight gain from AP's and dont want to double up as I am taking quetiapine already. For what it's worth....my sleep hygiene is very good. I've started exercising in the morning before work. I work as a credit analyst and sit in front of a computer from 9 to 5. HOWEVER...my insomnia is causing me to nod off at my desk which is unacceptable. Any tips/ideas/recommendatins are welcome. Mikl_pls I'm looking your way as you are the resident amateur psychopharmacologist. ;-)
  13. Hi all. I hope you can help me or give me some advice. I quit klonopin and gabapentin (first tapered one and then the other) and since then nothing but constant panic attacks anxiety and no appetite. The reason I stopped these was because I could not eat anything and I wasn't sure which med was the culprit. I recently read that gabapentin can cause loss of appetite and figure this med is the problem. I tapered from 1500mg/day to 600mg. I took 600mg last night and my doc told me I could go ahead and take 300mg tonight and be done with it. He told me that I should take each lowered dose for 3 days until I was down to 600mg. I have one day left and then within 40 hours it should be out of my system. I've been on gabapentin a few months starting with 600mg and going up slowly but ever since starting I have had trouble eating. I thought it was my anxiety but now I'm not sure. My current meds are only Effexor and ativan prn. I've tapered everything that wasn't having any significant effect. I know for sure that Effexor works for my depression. I've been on it for probably 15 years and I doubt it's causing my appetite issues. Thank you.
  14. Does anyone else find that the days you take your stimulant, you sleep like baby at night and wake up refreshed? I do! I'm so happy that I am finally getting restful and conistent sleep with the help of Adderall. I take 10mg IR once in the morning and sometimes I take a second dose around lunch or dinner. I was reading good article abut it. Let me get the link. It's from Tuck.com. If it's accurate information, it seems very informative. https://www.tuck.com/stimulants-and-sleep/
  15. I'm having a hell of a hard time and experiencing rather weird symptoms. Whether they've anything to do with Mirtazapine (Remeron) is something that I strongly feel but can't quite convince any doctor of. I was put on 15 mg of it in spring 2015 for depression and a severe insomnia - I hadn't slept an hour like since 25 nights back then! The benefits showed immediately within a day and surprised myself and my family. I would sleep well and be in a very happy and cheerful mood. Then however, from summer 2016 I developed some strange food intolerances; caffeine, sugar, fruits containing high amounts of fructose, yoghurt, butter and so on. Eating anything of that would cause me jitteriness and insomnia. I steered clear of those foods. From autumn last year though, a lot of those food intolerances have relented and it changed into intolerance towards medicines and supplements that I was on; the thyroid medicine for hypothyroidism, Vitamin D, Calcium, Vitamin E and could never again tolerate any new medicine or supplement. Symptoms resulting from these are, again, jitters, insomnia and a strange kind of feeling of being struck on the head, like I can't hear anything and the thinking becomes very unclear and blurred. Coupled with this is a weird sensation that if a medicine has any potential side-effect (even physical, such as urine retention), I get it at all costs. So I'm steering clear of the culprits here too. However, avoiding the culprits doesn't end my misery, it just helps in avoiding a whole new set of symptoms, because since autumn 2016 I'm under constant brainfog anyway, have heart palpitations immediately after every meal (but worst after breakfast), have concentration and focus issues, lead a life without any hobbies, wishes or desires. Nothing excites me, nothing interests me and nothing catches my attention. Leave tasks pending for months (the most unlike me habbit), have badly lost my sense of humour. My sense of humour was something that I literally used to pride on, and friends from around the world would call me to fresh up if they were having a dull day. My mind feels numb, although it isn´t as if it´s the sedating effect of the Mirtazapine because 90% percent of the nights I don´t sleep well, and on a lot of nights I feel as if I´m asleep with an awake mind! Amidst all this, although initially not effected for the first 17 months, but the libido is not non-existent. If I get them at all, my erections are very tiny and hardly last a minute. The GP who put me on it considered it to be just the effects of anxiety and depression and recommended the doubling of the dose to 30 mg. When I contested that, given that I´ve my doubts of a lot of these issues being brought upon by Mirtazapine itself, she referred me to a psychiatrist. He too strongly denies of Mirtazapine having any hand to play on it and instead thinks it´ll be best to combine it with another antidepressant for day-time. He put me on Paroxetine, boom, a flood of side-effects! Then changed to Fluoxetine (Prozac) - third day on it and having weird feelings. The heart poundings are one and is in fact making me very depressed and hopeless!
  16. I had gone back on cipralex because I was still having mood swings and anxiety on Remeron. I feel less depressed but I can't sleep. Took 2mg ativan to help me to sleep. Still awake.
  17. Hi there, although I'm a new member I've been lurking the forum for years . Long story short , I've had a psychotic break/near death experience that lasted for about a year , that occured in 2013 . Although I'm over 90-95% of it, I'm still suffering a backlash in terms of constant to variable anxiety throughout the week . I've also haven't slept naturally since the event occured in 2013 . So basically my body's used to feeling anxious for so long that its the new normal and ditto for the insomnia . I have a psychiatrist that I see 1x to 2x a month and am seeing a good experienced therapist twice a week (both work in the same office). I want to sleep naturally again . Anyways after trying multiple (sedating) anti psychotics , anti depressants, anti convulsants , 6 different benzodiazepines, z-drugs , antihistamines and belsomra , my psychiatrist decided to put me on Xyrem . I'm on the max dose of 4.5 grams twice nightly .The first two months were heaven, it truly was the holy grail . Absolutely zero side effects and completely unoffensive like a hypnotic benzodiazpine . The major payoff was that I was sleeping 8-10hrs a day and feeling so incredibly rested (like natural sleep since it only improves sleep architecture and induces natural sleep)I didn't need to take medicines like nuvigil and adderall to stay awake/function during the day and totally went off of the stimulants . My physical and mental abilities were 100% again . Workouts were great with all the new energy and school went from difficult to moderately easy now that my brain was finally recovering at night . Problem is that due to increasing situational anxiety due to school/(I guess how the near death experience makes me act to stressors ?) The 9g a night barely keeps me asleep for more than 3-4 hrs . The Xyrem pharmacist said insomnia people like me can use higher doses , as he's seen up to 13g a night . Problem is that the doctor said he will aboslutely not go past 9g a night . He will not Rx me any controlled CNS depressants with the xyrem (benzos, z-drugs , belsomra even friggin Lyrica is off the table) He's given me zyprexa since it has helped my anxiety and insomnia in the past however that antipsychotic leaves me with carry over sedation in to the day and dumbs me down (in an engineering science major) . The zyprexa does keep me alseep with the 9g of xyrem but I need a whopping 10mg to 7.5mg depending on my anxiety and stress level . Fast forward to today , as I lost my insurance with the xyrem prescribing psychiatrist and xyrem medication . I saw one sleep doctor at a sleep clinic and he said my insomnia was out of the scope of his practice, despite asking for xyrem and showing him my med records showing him I was Rx'ed it for months with little issue . I have an appt. with another specialist at a sleep clinic in NJ who Rx's Xyrem june 7th . And in case that lady is a spineless waste of money , I have two other sleep doctors lined up with appointments in late july who also prescribe xyrem in late July. Any tips on how to get this med back to helping me ?? I'm officially on 4mg Klonopin, 40mg paxil, 200mg Lamictal, 1mg Halcion (useless now) seeing different therapist and psychiatrist for insurance reasons
  18. I've been using a small dose of seroquel (25-50mg) nightly for sleep for around ten years. It has now stopped working. Every time I've tried to stop it I go into intense insomnia and withdrawal. My Doc has order 2.5-5mg zyprexa to replace the seroquel. Has any body experienced this protocol and is there going to be seroquel w/d when I switch. Thanks in advance for responses Ajax
  19. I've been titrating Seroquel down from a dose of 600mg XR and I'm now down to 0mg. I've been titrating slowly, without going cold turkey. Because of the way Seroquel XR is formulated, you have to drop from 50 mg to 0. It is worth noting that I'm being treated for Post Traumatic Stress Disorder, not schizophrenia or bipolar disorder. I'm in the process of taking Prazosin (minipress) and titrating it up to a therapeutic level and now that I'm up to 20 mg of Prazosin, I'm feeling okay in general. Prazosin is an alpha 1 adrenergic receptor antagonist in the same way that seroquel is - hence the change in medication. I reduced the seroquel from 50 mg to 0 mg on Thursday night. I slept fine on the Thursday, but by Friday afternoon, things fell apart. I became irrationally suicidal. I had a large amount of medication due to weaning off seroquel, titrating up the Prazosin and also taking 300 mg of Pristiq per day. Since then, I haven't slept more than 4 hours a night. I can't seem to get to sleep before 5 am, and I wake after a couple of hours at best. The insomnia is intolerable, I just can't drift off to sleep. I'm thinking that I'm going to have to go to the GP and get some sleeping tablets.because I just need something to get me to sleep. My psychiatrist has been really unhelpful, he tells me to just take enough seroquel to make me sleep, but I don't want to do that. I feel like if I do that, that I'll never get off the seroquel. I need to be able to sleep because I'm a law student, and my trimester is starting in a week's time. How long will the insomnia from the seroquel last?
  20. Hi there, I'm new on Crazyboards but have benefited as a visitor from many a post. I have a rather unusual request/question. I have sleep anxiety like nobody's business. What I mean by this is that I worry/obsess that I won't get enough sleep AND if I wake up in the middle of the night and can't go back to sleep I get out-of-control anxiety and then, of course, can't fall back to sleep. I sweat, get heart palpitations, GI issues, you name it. And the horrible thing is, these symptoms go into the next day and then usually continue into the next night. The thing is, before all this happened I was always a naturally great sleeper. I could sleep anytime and I loved my sleep. This all started years ago when my first child was born. I went on Paxil and it worked great except for bad side effects. I have since gone off Paxil and had quite a few "sleep anxiety-free years" (always had GAD though). But this has started to rear its ugly head again, off and on for the past couple years. I have started Trintellix and have worked up to 10mg. I have also taken .5mg Klonopin for years. When I started the Trintellix my pdoc bumped me up to 1mg Klonopin but it's not working (!) and this COMPLETELY freaks me out. I have basically been going to sleep at 11:00, waking up at 3:00, and MIGHT get an additional fitful hour in there by about 5 or 6. I have started CBT (Cognitive Behavioral Therapy). I'm doing it on my own for now, using a workbook called The Anxiety and Phobia Workbook by Edmund Bourne. I understand basically that I need to change my thinking about this problem if I am to make any progress. But this is extremely hard for me to imagine doing. What I am asking for is for feedback from people who have gotten only 4 or so hours of sleep a night for a period of time AND IT HASN'T RUINED THEIR LIFE. I need to be able to tell myself that this isn't the end of the world to only get 4 hours of sleep for a while (and this will be indefinitely until, hopefully, the CBT starts helping). I'm not working on an insomnia plan because I don't have sleep problems per se; I have major, unbearable ANXIETY problems that make it impossible to sleep. You might be wondering why I started the Trintellix: it is for the sleep anxiety but also for pretty intense GAD. However, I am really, really hopeful that I can manage this with CBT after some time. I may need to stay on the Trintellix, but the sleep anxiety is so horrible (it continues all the next day) that I feel I need to at least try something besides meds. I thank you immensely for your reassurances
  21. Please can someone help. I am very stressed and worried. I am 19 weeks 3 days pregnant and have been taking 400 mg of quetiapine the whole pregnancy so far for physocosis, insomnia, and anxiety. Can someone please tell me if they have ever or is taking Quatiapine during pregnancy ??? If so how did it effect the baby, mentally.. physically.. please Help. I don't think me stressing about the answers to this is good for me and the child.
  22. I have idiopathic hypersomnia, which isn't as ravenous as it used to be and seems to be well-controlled with Adderall XR 40 mg (which is also for ADHD and to potentiate the antidepressant effects of my MAOI antidepressant, Emsam). But I also, ironically enough, have intractable insomnia when it comes time to sleep at night. This seems to have been exacerbated when I started the Emsam recently, which comes as no surprise as it did this the first time I was on it the first part of this year. I understand the pharmacology behind selegiline and why it may be so stimulating for me, especially when taken with Adderall XR. But in any case, I've read insomnia and fragmented sleep is actually not uncommon with idiopathic hypersomnia. All the medicines I've tried for sleep either don't work (benzodiazepines and nonbenzodiazepines, I think I'm extremely benzo-resistant) or they may work but make me feel miserable and dysphoric and make me gain a ton of weight (certain sedating antipsychotics). Sorry for the long post in advance, but here are some lists that give some background info about my situation. ***************************************************************************************** Here is a list of the meds I've tried for sleep. Benzodiazepines: alprazolam (Xanax/Niravam) 2 mg: only works at ridiculously high doses, like 6 mg at a time, which I know isn't good for me, so I refrain from doing this unless it's an absolute must chlordiazepoxide (Librium) 25 mg: doesn't seem to work for sleep but does okay for anxiety clonazepam (Klonopin) 1 mg: again, only works at ridiculously high doses... clorazepate (Tranxene) 15 mg: doesn't work at all for anxiety or sleep or anything diazepam (Valium) 10 mg: this one is like playing Russian roulette, either it works (10-20 mg), or it doesn't work, or it actually stimulates me and keeps me from sleeping estazolam (ProSom) 2 mg: this is another one that I have to take supratherapeutic doses of (4-6 mg) to work, 2 mg just doesn't cut it at all lorazepam (Ativan) 1 mg: this benzo literally does nothing to me except make me feel like I have Alzheimer's disease due to its apparently extremely strong amnestic effects oxazepam (Serax) 30 mg: does well for anxiety at 30 mg, but nothing for sleep whatsoever temazepam (Restoril) 30 mg: works at high doses like 30 mg and above, but makes me feel miserably depressed the next day, and all I can do is lay in bed or drag around if I manage to get out of bed) Nonbenzodiazepines: zolpidem (Ambien) 10 mg: doesn't work well at all, even in supratherapeutic doses zolpidem CR (Ambien CR) 12.5 mg: works even less than regular Ambien, for some reason eszopiclone (Lunesta) 3 mg: this one was like taking a placebo... it literally did nothing at all for me... (3 mg) Even tried 6-9 mg and it still didn't do anything Antihistamines: diphenhydramine (Benadryl, Unisom) 25-100 mg: hardly does anything to touch my sleep doxylamine succinate (Unisom) 25-50 mg: does a little more than diphenhydramine, but also leaves me feeling hung over the next morning, and also feeling quite depressed hydroxyzine hydrochloride (Atarax) 25 mg: doesn't touch me hydroxyzine pamoate (Vistaril) 50 mg: used to be somewhat calming, but not sedating, doesn't touch my sleep even if I take 100-200 mg of it Antidepressants: nortriptyline (Pamelor) 50-150 mg: this wasn't prescribed to me for sleep, actually, but I listed it because I know it's used sometimes for sleep, and I wanted to say that it didn't sedate me even one bit... trazodone (Desyrel) 50-200 mg: at first this worked like a charm (and gave me auditory and visual hallucinations), but 50 mg soon became insufficient, so I went up to 100 mg, then 150 mg, then 200 mg, and it just quit working. I took 300 mg one night just to see if it would help, and it helped me sleep for 3 hours, but I woke up with my heart beating rapidly and pounding in my chest—scary experience, would not repeat... Antipsychotics: chlorpromazine (Thorazine) 100 mg: this makes me sleep for 15+ hours and when I wake up I feel like hell. The first time I took it, I had an acute dystonic reaction, which scared the piss out of me. I'm surprised I was brave enough to take it again (I guess I was just desperate). It also makes me gain weight, but not as bad as Zyprexa. olanzapine (Zyprexa) 5-10 mg: also made me sleep for about 12-15+ hours, and when I wake up I would feel like hell, plus it made me gain weight like crazy without altering my diet, and it made my fasting blood sugar skyrocket into the 200's. quetiapine (Seroquel) 100-300 mg: at 100 mg, no help with sleep; 200 mg, I get help with sleep but I feel like hell the next day and gain weight; 300 mg is even worse than 200 mg and has no antidepressant effect for me despite what is purported by all the psychopharmacology textbooks out there. Saphris (asenapine) 5-10 mg: works perfectly for sleep—helps me get just the right amount of sleep, and it's weight neutral; however, despite an initial antidepressant effect when first taking it after not taking it for a while, I always end up feeling very dysphoric and depressed the morning after I take it after taking it for a few weeks, and end up having to stop taking it. It also has started to exacerbate the akathisia that is being caused by another one of my medicines, Vraylar. α2-adrenergic agonists: clonidine (Catapres) 0.1 mg: made me sleep alright, but made me sleep forever, and when I woke up, I felt super teary, dysphoric, depressed, and miserable, and couldn't get out of bed all day Orexin receptor antagonists: Belsomra (suvorexant) 20 mg: this was hit or miss. It would work like a charm sometimes, and sometimes I would just toss and turn all night, unable to get to sleep. But it doesn't matter because my insurance gave me the middle finger last year with a nice little letter saying that they would no longer pay for it anymore. Melatonin receptor agonists: Rozerem (ramelteon) 8 mg: did absolutely nothing for me Natural remedies: Melatonin 1-10 mg: I've heard using a sustained release plus an immediate release sublingual tablet is the way to do it, and use the lowest dose possible for each one, so I wound up using 3 mg SR + 1 mg IR SL, and it seemed to work pretty well for about a week, but its benefits started to wear off, and I started feeling depressed more during the day. When I stopped the melatonin, the depression eased up. Valerian root: this actually stimulates me. Lemon balm: anything with lemon balm actually does help me sleep somewhat okay, but I have to watch out for what else is in it Lavender tea: this actually helps quite a bit, but it's hard to find where I live L-Theanine 200-400 mg: supposed to help relax you and help your quality of sleep, but I didn't get any benefits from it. I don't even feel the relaxation effects from it. Ashwagandha 500 mg: didn't help me sleep, but did help ease the nightmares I was having while going through Effexor withdrawal Scullcap 1275 mg: didn't help me sleep, but like Ashwagandha, it helped ease the nightmares I was having while going through Effexor withdrawal Chamomile: just helps me feel relaxed, doesn't help me sleep (probably more I can't think of off the top of my head...) ***************************************************************************************** Here is a list of meds that I haven't tried. Benzodiazepines: flurazepam (Dalmane): my pdoc refuses to prescribe this one to me and given how long its half-life is, I don't think I'd want to take it anyway midazolam (Versed): I somehow feel like this would work, but it's so short-acting, and I doubt my pdoc would prescribe it to me Onfi (clobazam): not sure if this would benefit me for sleep, I think it's indicated for Lennox-Gastaut syndrome triazolam (Halcion): Very short-acting, not sure if it would benefit me through the whole night Nonbenzodiazepines: Edular (zolpidem sublingual): I was interested in trying this, but it's not covered by my insurance... bummer. zaleplon (Sonata): another short-acting sleep med, which I doubt would be helpful at sleep maintenance ZolpiMist (zolpidem oral mist): I was also interested in this one, but my insurance doesn't cover it either... T__T Barbiturates: Butisol (butabarbital): seriously doubt my pdoc would prescribe this, but I wonder if I'm really to the point where I need a barbiturate... Seconal (secobarbital): see above... Antidepressants: amitriptyline (Elavil): I've heard of this one being prescribed for sleep, but I'm afraid of the weight gain. doxepin (Sineqan/Silenor): I've been curious about this one, but afraid of it because of weight gain. My pdoc at one point acted like she was going to prescribe it for me, but it was just not on my prescription sheet, like maybe she forgot? Or decided it was best for me not to be on it? imipramine (Tofranil): I've heard of this one being prescribed for sleep too, but I think it's contraindicated with MAOIs. (certain TCAs can actually be taken with MAOIs) Antipsychotics: risperdal (Risperidone): I've heard of this one being prescribed for sleep, but not too commonly... I'd be afraid of the hyperprolactinemia associated with it. Plus I would really rather take just one antipsychotic if I can help it... I don't want to be on one for mood and one for sleep... Other Xyrem (sodium oxybate): I feel like this would really help me what with my fragmented sleep and poor sleep quality, but my pdoc won't prescribe it (maybe she isn't licensed to?) I may need to find a sleep doctor for that if I want to pursue that. The only problem is I don't have narcolepsy, and I've heard it's next to impossible to get your insurance to pay for Xyrem if you don't have a diagnosis of narcolepsy, but I have heard of it being used off-label for idiopathic hypersomnia-associated insomnia as well as insomnia itself. ***************************************************************************************** Can anyone give me any insight into what I could possibly do for sleep? I feel like I've kind of hit a wall here. I've also tried relaxation exercises, guided meditation, binaural beats, and that kind of stuff, none of which worked for me. I know I gave a lot of info to sift through, sorry for the super long post... But any feedback would be appreciated. Thanks!
  23. I had to quit lithium because my kidneys are damaged. I have been reducing the dose over the last month under the guidance of my pdoc and took my last dose of 200mg last night. My ddoc warned me that I could become manic as the lithium level drops very low and goes out of system altogether. Has anybody become manic on the discontinuation of lithium? If so did it occur gradually or very quickly I'm already having trouble sleeping and am not tired and a bit concerned that this is the start of mania, although I have no other symptoms. Maybe I am being paranoid!! It's just that my mood has been very stable for a long time now, so I am a bit worried. Also do you think that the introduction of valproate may help help prevent mania??
  24. Posted same topic twice Moderaters, could you please delete this so no confusion. Thank you!!!
  25. Hi I have just joined here out of desperation. It's a long story but feeling as if I can't carry on at the moment. I had severe post natal anxiety, insomnia and depression 10 days after giving birth 4 years ago. was put on mirtazapine 45mg which got me back to myself for a year. I tried to go on contraceptive pills microgynon and loestrin both of which sent me spiralling back into the worst depression. Stopped these and couldn't really get over the hormone problems so added venlafaxine 37.5mg to mirtazapine which worked great for a year. Since December 2015 I have had to increase my venlafaxine 5 times so now I'm on the top dosage of both venlafaxine and mirtazapine. My relapses always happen 10 days before my period and I get so bad I can't even function and have suicidal thoughts so I have to increase my tablets. I am 4 days in to my last increase and 5 days before my period and I just can't cope. My doctor has given me a prescription for a progesterone only mini pill, he has said to take this after my period so middle of next month when I'm feeling better but I am PETRIFIED that it will make me even worse and I can't increase my anti depressants. I honestly feel if this gets any worse I will have to hospitalise myself as I am so tired of fighting this awful thing and it never gets better. I have cervical erosion since the birth of my daughter and had this frozen two months ago and since this my last two periods have been hell and I feel as if I'm having a breakdown. My GP says this procedure wouldn't have affected my hormone levels. I also take supplements Agnus castus, vitamin B6, magnesium, calcium, vitamin d, evening primrose oil, vitamin b complex food supplement and exercise when I am feeling well. I just don't know what to do anymore should I take this contraceptive pill? If anyone has any experience or advice please please contact me I am desperate. Thank you
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