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Found 87 results

  1. I'm just wondering if anyone else has had the experience of feeling completely exhausted when taking immediate release Wellbutrin/Bupropion? My doc started me low - at 75mg a day (37.5mg twice per day), then up to 150 (75mg twice per day) for about a month now. For the first few days I felt the "honeymoon" effect some people experience- increase in energy, motivation, etc. After then, however, I've noticed I feel very tired. It's not a crash after some initial energy, I am just exhausted soon after taking it. Moodwise I am ok, and even notice I feel a bit calmer. Definitely not the energy, motivation and rage other people report. I've been on a variety of AD's for the past 30 years and have taken Bupropion in the past, with some success. I remember feeling depleted on the XR version but switched to the IR version and felt fine. I also take dexedrine for ADD and that helps counteract the tiredness, but if I forget I'm exhausted. I know this is a paradoxical response, as is some of the water retention that I've noticed as well. I asked the pharmacist and she said that it is possible to feel tired from bupropion but didn't offer much else. I'm curious if, of those who do feel tired on this med, do you still feel like it's working in other aspects, or is this side effect a sign it's not the right one? If that's the case, I suppose taking it at night could help but I'm more curious about why I have the opposite reaction than everyone else.
  2. I just started taking Wellbutrin and have been currently taking it for 3 days now and I’ve been getting multiple symptoms listed from the Wellbutrin. I’ve been having stomach pains, nausea, dizziness and headaches, should I stop taking the Wellbutrin if I have these effects or would they go away after the first 1 or 2 weeks?
  3. I have finally decided to go off Wellbutrin (Bupropion/Zyban) as I just cannot live with this anger and rage attacks any longer. I spend my day swearing, (I can’t fit enough swear words in a sentence), clenching my hands until they are rigid, screaming and hurting my throat, telling myself I wish I was dead and having even more intrusive thoughts than normal, even thoughts that wake me up in the middle of the night and I respond by telling myself to fuck off while I‘m laying there in bed. The anger has alarmed me and I can feel the cortisol surging through my body. I’m getting off this medication by myself without help because I went to see my psychiatrist the other day sand he virtually dismissed me and was clearly annoyed with me for having too many side effects and he was frustrated at how difficult I was to treat. There was no sympathy whatsoever. He said we’ve exhausted all avenues. I felt like a fool for not responding correctly to medications that he thought should work. It was a waste of money seeing him and I’m sick of doctors telling me it’s worth having numb genitals or inability to orgasm if you find a pill that gets rid of your depression. The doctor was frustrated with me before for all the pills I’ve been on that I couldn’t tolerate because of sex issues. The Wellbutrin didn’t do anything negative for me sexually (it seemed to have a big improvement on me sexually, actually), but the insane anger is just too much to live with. The anger was over the most minor of things, such as the vacume cleaner cord getting tangled, or losing internet connection. I’m currently on Lamotrigine 200 mg by itself which I hope will help my depression/anxiety.
  4. Hi all, I am new to posting so bear with me, but I've been reading these boards forever and been helped by them so much, so thanks to all of you. I have been taking Wellbutrin XL 150 off and on for a couple years. I went off for a couple months in the summer bc I was doing well, but then went back on in around September. Around November I started to notice jaw pain and tension, so I figured I was clenching during the night (I've always had TMJ problems so this wasn't that surprising). What was surprising was then I started to grind my teeth even when I was awake, or even just kinda open my mouth. If I really thought about it I could stop, but when I started thinking about something else I would find myself doing it again, so creepy! So finally after reading other Welly-bruxism experiences, I went off it, only to become depressed again. The thing that was so weird, was in 2017 I took the med for like ~8 months solid without any bruxism. So recently I tried going back on Wellb, thinking maybe those side effects were a fluke...but they seem to be back, which is terrible bc Wellb works for me in every other way. I am trying it now with added Buspar, 20mg a day, but so far (like 10 days in) it's not helping the jaw movements/grinding. Has anyone else had this, especially the day grinding? Did anything help? Aplenzin has been coming up on this board a bit, could the different salt make the difference, do you think? My doctor wants to try me on Fetzima if the Wellbutrin grinding doesn't go away...but its reviews are soooo mixed/mostly terrible. SSRI's don't work for me, the only SNRI I've tried was Effexor over 10 years ago and it was crappy. Any ideas either Wellbutrin alternatives or bruxism combating add-ons would be super helpful! Thanks
  5. hey there! I recently started seeing a new psychiatrist since my drug regimen of the last 3 years has plateaued and my old psych was terrible. This new doc seems to know what she's talking about and I like her. Basically my antidepressants have hit a block and feel like they've stopped working. So she suggested adding a little helper on top of what I'm already taking. Her first request was Wellbutrin, BUT when I mentioned that I use an albuterol inhaler for my asthma she said that Wellbutrin and albuterol have a bad interaction and pretty much threw out the idea of trying out Wellbutrin. She put me on 2mg Abilify instead. It's only been a week but I'm not liking the immediate side effects of Abilify that I've been experiencing and hopefully it will even out eventually. BUT in case it doesn't I want to be able to have other options. I've heard so many good things about Wellbutrin. When I tried looking up Albuterol and Wellbutrin interactions I've come up with NOTHING. even on the drug interactions checker. So my question is, has anyone ever heard of this before?? If so, what exactly is the interaction??? If nothing comes of this, I'll ask the new doc about it when I see her again in a month, but for now it's really killing me to know!
  6. I have bipolar II, and I have been hypomanic for about two weeks. I would like to come down now, because the lack of sleep is getting to me and I'm not that euphoric or even productive anymore. I'm trying to utilize the extra energy while making reasonable choices to not go higher up, but at this point I would just like to come down and get some sleep. I'm wired physically and sitting still is close to impossible, but it feels like something in my brain is tired and needs to rest. Evidence says I'm not at my best right now, at least I don't code as well as I usually do, even though I have a lot of ideas and every thought that comes through my head feels like the best idea ever. I'm not taking a mood stabilizer and I don't think I really need one most of the time. Most of them wouldn't be worth the side effects, since antidepressants actually helped somewhat with the depressive episodes while not preventing all of them and hypomania is infrequent. I rapid cycled in the beginning, but I don't since switching to Wellbutrin from Zoloft. Also I stopped doing insanely stupid things while hypomanic after I understood what it was and got some practise dealing with it, and I don't tend to crash into severe depression although it has happened. I would have considered cutting the Wellbutrin in half if my 300 mg pills were splittable, which they aren't because they are sustained-release. The only thing I have on hand that could help me sleep is Remeron, but I don't know how smart it would be to take an antidepressant just for the antihistamine side effects. It helped a great deal in the past when I was depressed, so that's why I'm unsure about taking it now. If anyone has ideas about how to get down from here safely and preferably soon, I'm all ears. I could use more than two - four hours of sleep tonight, and the time says that's probably not happening. In an ideal world I would be discussing these things with a psychiatrist, but I don't have one since moving six months ago. I have a therapist, and I have an appointment with her this Friday. I could ask her to ask a doctor to prescribe something for sleep, we talked about it last time I was there, but I don't know what and I won't just take anything. I'm never taking antipsychotics again, not even at a low dose. I have tried four, and I tend to get terrible akathisia at low doses, and then sleep most of the day at higher doses. I got them while I had depression with psychotic symptoms before I was diagnosed bipolar, and they didn't even help with that. The thing is I'm not prepared to take medications with life-altering side effects just to prevent hypomanic episodes that are far between and usually don't end in long-lasting depression. Maybe just a short-acting sleeping pill for a short period of time or something like that. I don't know if the whole antidepressant monotherapy thing is a good idea either considering I'm hearing voices from lack of sleep right now (don't worry, I've been there before), but it's been way better than atypical antipsychotics at preventing depression with none of the side effects and Lamictal literally did nothing for preventing depression or anything else. Any ideas about what I could do after this long ramling post is greatly appreciated. Medication-wise or non-medication-wise.
  7. How do I wean off Zyban/Wellbutrin XL safely? I can’t cut them in half as they are XL and you can only get XL in my country and you can’t get smaller pills either. I can’t see doctor for a while. The pills are the smallest dose ones.
  8. I was diagnosed bipolar about 7 years ago around the same time as my first suicide attempt. Long story short - I rejected the diagnosis and eventually went off all meds because I thought my issues stemmed from the stress of nursing school. School over - no meds needed. About 3 years later, started seeing a new psychiatrist and taking antidepressants. I actually felt like I had my life back... Then, at some point recently, my son died. I had an affair. My husband and I had another child. And then affair was discovered by my husband. The intense guilt and depression led me to try to kill myself, and I recently endured my first psychiatric hospitalization. Wellbutrin and buspar were once my miracle cocktail. I'm still on those, plus lamictal, plus latuda. Latuda is not helping me. It may have cleared my suicidal thinking, but over all... I feel lost, stuck, hopeless, and let down. I've reached out to my psychiatrist for help so many times, and I'm screwed over by the incompetent office staff each time. Can someone just tell me it gets better? Do I even deserve better after what I've done? I'm paranoid and delusional. My intrusive thoughts seem worse each day. I want to believe it gets better. Ive dropped down to working part time and I'm seriously considering quitting. It used to be that I only felt competent at being a mother. But now I don't even feel I can do that right. I'm a mess. Is there any hope? If a med didn't work for you, did you find a med that did help? I want to feel like myself again... I feel so let down that latuda isn't helping me. Thanks for listening...
  9. I've read on here that people are experiencing anger when on Wellbutrin and after reading that I'm wondering if that is happening to me also. I had thought the anger was independent of the drug, but it's getting worse and now I'm concerned it's the drug. I'm on 150 mg. I'm also on Lamictal 200mg. Would increasing the Lamictal help with anger, or is there something else that would help, not of the SSRI variety. Obviously I'll talk to the Dr about this but at over $100 per appointment I can't seem him every week. I could put up with the anger, but it's turning into rages and I feel exhausted afterwards and I have a sore throat from screaming.
  10. hello, new here. i found the board by googling two of my meds interactions. went to my psych today and got a new med... read about two of my meds interaction and lowkey i'm terrified lol. list of all drugs/substances i take once a day, all in the morning: 300mg bupropion qd 400mg lamictal qd 10mg generic zyrtec "women's" multivitamin 5000mg biotin birth control pill as needed: 30mg zenzedi OR adderall. i only take half at a time, and not every day, though i do most days 5mg ambien (take ~5x a week) my depression has been terrible for the last year -- tbh since the election. dropped out of Uni fall semester last year and haven't been since. i have been lazy, 100000% unmotivated, reclusive, gained 30lbs in less than 2 years etc etc. i don't want to leave the house to see my friends and family because i am embarrassed about my weight gain (also because of the reclusiveness i mentioned). after talking with my psych, she suggested adding 5mg Trintellix (Brintellix?). she mentioned that the most common side effects were nausea, diarrhea etc etc. she said that if it seemed to be helping i could lower my wellbutrin dose and perhaps stop taking it entirely (trintellix being its replacement). after leaving her office i did what any other millennial would do and googled the medication. there is a LOT of information about the possibility of serotonin syndrome being a side effect - i read somewhere 15%???? that seems low but like google it - it sounds terrifying. combining wellbutrin + trintellix has a "MAJOR" interaction per drugs.com, which states that the risks outweigh the benefits when combined. i immediately left my psych a message telling her basically what i said but less crazy (pfff lol) sounding. she called back and said that she's never seen that, it's very rare, she's met only one prescriber who reported it in a patient, and it's usually at higher doses. i feel a little better but still a bit nervous. not really sure what i'm expecting to get from this post but i'm so annoyed with taking a millions meds and i keep seeing deaths reported by combined meds, often including (not limited to) adderall and ambien. like i'm in my early 30s, i don't want to die in my sleep.... anyway, hi!
  11. I have been on Wellbutrin SR twice a day for at least 6 months. The other day, I forgot to take my morning dose until about 5pm. I think I then took my evening dose at 9pm that night. The next day, I forgot to take it again until about noon. Although my anxiety was warranted, to some extent, it was WAY higher than it normally is even when I fear a conflict is going to happen. Could my Missed doses have anything to do with this increased anxiety?
  12. Psych Dx: treatment resistant depression (major + persistent), generalized anxiety, adhd Psych Rx: bupropion 450 qd, buspirone 15 bid, adderall 20 am 10pm, clonazepam .5 prn Other Dx: celiac, gerd, vulvodynia/vulvar vestibulitis, oab, seasonal allergies, idiopathic chronic nausea, neuropathy, myalgia, & arthralgia Other Rx: myrbetriq 50 qd, pantoprozole 20 bid, topical estrogen qd, topical clobetasol prn, topical lidocaine prn OTC: mucinex 12-hour bid, vitamin D3 qd, fish oil qd, probiotic qd, zyrtec qd, nasacort qd, saline spray bid, melatonin prn Previous Psych Rx: seroquel, depakote, lamictal, remeron, trazadone, lithium, ambien, sonata, zyprexa, lexapro, prozac, temazepan, xanax, rozerem So I've clearly been on a lot of meds over the years (since first being put on seroquel in early 2013) partially because I was initially misdiagnosed with bipolar disorder. I've been on my current cocktail for quite awhile, and I had been doing pretty well with my depression but it's gotten significantly worse lately due to some life events + unyielding chronic pain that has been getting worse for the last two years. For the neuropathy I tried gabapentin for several months and it did absolutely nothing. I've been suggested Lyrica (which even with my good insurance is still $100 a month or $200 for 3 months with a mail order pharmacy which is a lot more than I can reasonably afford) and Cymbalta. Does anyone with depression and/or neuropathy have any experience with taking Cymbalta and Wellbutrin together? The two SSRIs I've taken (lexapro & prozac) in the past both gave me severe gastrointestinal side effects and I wasn't able to stay on them long enough to see if they even helped. It would be great to have a cheap, generic drug improve my nerve pain and depression, but I'm nervous about trying another SSRI. I'm also fairly uncomfortable with the idea of going off bupropion, bc it's been pretty damn effective if not adequately so. Because when I wasn't on bupropion I was a MESS and I'm afraid of going back to that level of depressed. Also curious if anyone has any success with using any med, Cymbalta or otherwise, as an adjunct treatment for depression? I have recently gotten back to therapy so I'm hoping that will help some but it's hard to follow through on anything from my therapist (or from my physical therapists, doing anything besides going to work & sleeping) bc of executive dysfunction, constant fatigue, pretty severe anhedonia, general feeling of emptiness.
  13. I am a 28 year old female who recently was perscribed Wellbutrin 150mg per day. I had heard all of the stories about people's sex drive going through the roof, and so I was excited to start taking it. However, on day two, I noticed that I was having a difficult time achieving an orgasm, so I IMMEDIATELY stopped taking it. It's been two weeks, and I still don't feel back to normal and I am officially starting to panic! I'm a pretty high strung person if you can't tell, and I'm wondering if I'll ever be normal again. I can still get really turned on, but my orgasms aren't as strong and today I could not have one at all. It seems impossible that only two pills could have messed me up like this, how could that be possible? It will have no return to normal right? Has anyone else out there experienced this after taking such little medicine, and how long did it take to go back to normal? ANY advice, answers or comfort anyone can give me would be awesome, I am really starting to get worried!
  14. Hi y'all! I need your help. I guess I need some encouragement, more than anything. I restarted Wellbutrin XL 150 and Prozac 10 three days ago due to mild depression and generalized anxiety disorder. (I say "restarted" because I had been on both meds for about 4 years, went off them last year, tried Trintellix for about 8 months, got off of that and here we are.) Anyway, I anticipated the lack of appetite, the feelings of having had too much coffee, the sweating, and dry mouth. But now I'm having extreme nausea a few times a day and a severe flushed feeling. And tonight I started getting numbness/tingling in random spots all over.. It started on my cheek and my lip (felt like a cat hair I couldn't wipe away) and bounces around to my nose, fingers, toes, and knees. It's really freaking me out because I've never felt this before. How long will these unpleasant side effects last? They almost threw me into a panic attack but I laid down and focused on my breaking and got myself out of it but I'm still having a rough time. I just want to make sure this is all par for the course and nothing too dangerous is happening. And that it'll all subside soon. Thanks in advance. ❤️
  15. It's only day 2, but I haven't really had much in the way of side-effects yet. I've been expecting the startup effects to be be somewhat difficult. Can anyone comment from their experience or technical knowledge whether they might start later?
  16. Sorry to those I'm annoying with post. I try hard not to bomb the forums with my problems...and there are plenty. So I'm at a point now where I have to adjust my medication. And one of the options is to add Wellbutrin to the mix. Since coming down to 75mg Effexor I've lost a lot of weight...unintentionally...I just don't seem to have much of an appetite. I tend to have a very anxious-type depression. And after reading side effect profiles for Wellbutrin I'm concerned. Losing weight adds problems to depression/anxiety as most of you probably already know, less serotonin over the last months from food and drug. So Wellbutrin having the effect of upping anxiety and hurting my appetite further sounds catastrophic to me. It's a popular medicine so I was just wondering how everyone here did on it? Like for anyone did you actually just feel better and start eating? Right now food has no appeal, so.... On the flip side I've lost a lot of interest in things and heard Wellbutrin can help that? Thanks in advance.
  17. Hey all. First time poster. I'm currently not on any other medication. I'm 24 and after a long bout with lyme disease, I have been left with this really bad fatigue and increased anxiety and depression. So 3 days ago I started Wellbutrin XL 300 mg generic (I have no idea why she started me on such a high dose) Aside from the emotional ups and downs and irritability the constant has been I FEEL SO F****** TIRED! Like way worse than before I started. Absolutely depleted. Will this get better? Because fatigue is one of the primary reasons why i'm taking it, and nothings more depressing than feeling like the med that's supposed to help with that is making everything worse. I haven't had any honeymoon period to speak of, just straight up sleepy all day, which is funny because I was told to take it in the morning to avoid insomnia. Anyway has any one had this in the beginning and than it went away? Or is this just a bad sign....I'm thinking if I don't feel anything beneficial and the same daytime tiredness after 7 days I'm calling my doctor. What do you guys think? Hope this doesn't last.... Thanks!
  18. Hi all, I hope everyone is good. It must be going on 9 months since I posted here but I feel nothing has changed. I've been on Wellburtrin and Lyrica but despite working up the dosages I feel like it isn't working and was leaving me feeling drugged stupid and emotionally flat. So I have been tapering off but now I feel quite physically bad with, aches, pains and fatigue is back big time. Although I can think more clearly again being depressed all my thoughts are about negative stuff and death. I've no idea where to go from here now. Pdoc said increase Wellbutrin further and was on about adding in Lexapro but I've been down the ssri route before and they don't suit me. I have been reading up about alternative treatments like CBD oil, clinicial trials on drugs like Ketamine... pretty keen to try anything I haven't already tried at this point. Even stuff I used to manage when depressed, like going for a walk, has become incredibly hard this last month. I barely leave the house. No idea why I'm posting this probably just desperate for some kind of communication with the outside world.
  19. Has anyone had any experience with Celexa, Wellbutrin and Lamictal combo? I was on 300 mg of Lamictal up until a month ago when my pdoc added 20 mg of Celexa to help my depression. Yesterday (a month later) he added 150mg of Wellbutrin XL to help counteract the sexual side effects of the Celexa. Has this combo worked for anyone?
  20. Just wondering if anyone has experienced any kind of withdrawal symptoms going off Wellbutrin? I've only been on it a month, but I suddenly feel more destabilized, my depression is worse & now having some anxiety. btw it is the IR (300mg total, split morning/afternoons). It has given me sleep disturbance, which I now must remedy with Valium or Xanax. I don't know whether I should continue to stick it out?
  21. I know A/Ds usually take several weeks to kick in, but I thought Wellbutrin was one of the quicker ones? Some ppl mentioned 3-4 days. I'm very impatient because this is my 2nd trial, and after 7 days (just went up to 300mg) I feel nothing (except extreme dry mouth, problems swallowing) I guess I'm just looking for reassurance that this stuff (if it does indeed work) will at least show some benefit within the next week? I hope.
  22. Hi everybody, I'm new here and this is my first post! I am a binge eater and have struggled with BED for roughly the past five years. I have always been slightly overweight, as is my entire family, and we also have a history of yoyo-dieting and eating disorders in the family. My sister and brother were both nearly hospitalised as a result of anorexia, and I too went through a time on which I can now look back and say that I was anorexic and obsessed with exercise as a means to rid my body of what I had eaten. I am an opera singer, and while i was studying opera in 2012, I developed nodules on my vocal cords and had to withdraw from my course and all current and future engagements I had lined up. I was terribly depressed and anxious about what the future might hold, but mostly bored, and so I ate, and ate and ate. I gained and dropped weight over the next few years as food became a crutch for my anxiety--I tried to eat mainly salads and high protein meals, but whenever things went wrong and i felt chaotic and without a sense of centre, I would reach for food I didn't even really want. I would buy binge foods and eat them in secret in my room or in my car, or in (cringe) public bathrooms, and sometimes i would come to my senses half way through eating a supermarket bag full of food and go and throw the lot in the trash ( a huge waste). I went to see a CBT therapist who painstakingly tried to drag details of a tortured childhood (which i didn't have) from me, as a way to get to the bottom of it, and then gave me some mental exercises and an 'emotion wheel' worksheet to fill out at home whenever I felt a binge coming on. But I felt silly and like a pathetic child with a colouring book so I never really committed to that. Then phentermine (in the form of the pill duromine) came into my life, and I became addicted to it. I lost a ton of weight, and when it stopped working I doubled and then tripled the dose, making sure to fit in a bikram class, kickboxing class and 10km every single day on an almost empty stomach. I also became obsessed with the idea of intermittent fasting and would go days at a time not eating a thing. But i felt confident and happy and finally myself, free from the physical and emotional burden of extra weight. But of course, this rosy existence couldn't last for long. i knew I needed to stop taking phentermine because it was dangerous, and I was obtaining it illegally, and I had also noticed it was affecting my voice negatively and totally drying out my throat. I moved to scotland to study my masters in opera, and the first few months in this totally different environment, having to make friends and 'prove myself' as a singer in the international opera school there.. well, it was intimidating. And I ate, continuously and with reckless abandon, and gained weight. I was prescribed a combination of topirimate (starting at 25mg and worked up to 100mg every evening) and wellbutrin (150mg twice daily). Eventually I felt more settled, opened a gym contract and even got a lovely boyfriend who i eventually moved in with. i never really felt the medication made a difference, but I was feeling happier and more relaxed and so stopped taking it. I did continue to gain weight, and to eat foods that were previously 'forbidden', but I wasn't bingeing. Fast forward to now-- I have been living in Italy for a month and a half, taking a course in opera directing, and I would estimate I have binged on average 5 out of every 7 days I've been here. I don't know what is wrong with me, but I feel so isolated and anxious and unsettled and I cannot stop EATING. I always find it difficult getting used to a new place, and it is extra difficult when it is a foreign country, although I am semi-fluent in Italian. I do still have topamax and wellbutrin with me and have started to take it again. I think it is working and I don't feel nearly as hungry-- I don't feel that uncontrollable urge to binge-- But I am still bingeing. Why? I still feel like I HAVE to do it for some reason. The habit is so engrained. if there is food in the cupboard and the fridge, it must be eaten (even if it's something I don't like). I go to the supermarket, stand around for hours trying to make the 'right' decisions, end up making some slightly dubious ones, take it all home and eat the lot. I am unable to save things for later, or for instance, buy a slab of chocolate and consume a piece or two after dinner. I am still in the gym most days, and love to run, swim and lift weights--it makes me feel light and powerful and free--but I'm sabotaging myself every day with this terrible condition and I need to kick it.
  23. I'm making the transition to all generic because on my insurance the brand is exorbitantly priced. My Dr. submitted a form requesting they cover brand but to no avail. I have already switched my Wellbutrin 150mg XL to the generic several days ago and so far I haven't turned into newt. LOL Soon I will be switching to generic Prozac and Abilify. My biggest concern is that generic Abilify will have some funky side effects I cannot deal with. I'm only on 7mg. Does anyone have any experience with the generic form of Abilify? Any other advice is welcome.
  24. Hi all. This post is a last resort. No, I’m not suicidal. But I am on the verge of something — going back on full dose Wellbutrin, a drug that’s been both effective yet awful for me. I’m very desperate to find another solution. I've literally been trying for decades. I’ll explain as concisely and non-boringly as I can. I’m 43. I’ve been on 150 SR Wellbutin since I was 19 for depression (possibly mildly bipolar) and ADD. Initially it was a wonder drug — I went from being a C to an A student. I helps me stay productive and keeps me from getting depressed (I’m not happy on it, far from it, but not exactly sad either). But over the years, my side effects have gotten worse: anxiety, fidgety-ness, tinnitus, stuttering, restlessness, paranoia. I hate that everybody knows me as this stressed-out restless person when that’s not who I am. I’m trying to date and it’s tough when I’m so anxious. It's like I could never relax and enjoy myself. I want to believe there’s a better way, that I’m not broken and that with the right combination of food, supplements and exercise my brain will work properly without it. But increasing the dosage turns me totally nuts and lowering it tends to utterly crash my motivation and basic brain functioning. I have tried to quit many times. One time I got down to 100 mg for awhile — then I lost my job, so I hopped right back on. I have tried many, many other drugs too. SSRIs — including most recently Brintellix — increase my happiness (yay!) but also turn me into a total couch-snoring zombie (oh no). So those are out. Mood stabilizers like Lamictal have side or ill-effects. ADD drugs like Adderall, Monafidil or even Strattera boost my productivity, but then I crash and feel super angry and send ill-considered emails. Tried Pristiq, Effexor, etc. I once tried a bunch of natural things that bump dopamine (I'm a dopamine seeker), but that didn’t work. So a year ago, I got really serious about trying to quit Wellbutrin for good. I went to a shrink who specializes in hard cases. He thought some degree of reduction would be beneficial, he said my brain was like an engine that was being driven too fast (I know -- 150 mg isn't that much, but everything hits me hard). But he warned that he’s never seen somebody on a drug this long who successfully fully quit — “your brain starts to need it.” We started cutting back very, very slowly — like a mere 10% cutback every couple months. I also ramped up some other things. While I’ve always been relatively healthy, I'm working out four times a week and eating well. I take a bunch of supplements (multi, b-energy, ginkgo, astragalus, vita D, pterostilbene, vita c, CQ10, acetyl l carnation, cod liver oil, coconut oil, green spirilla powder). I drink green and chaga tea. Meditate a few times a week. I’m trying everything I can to give my brain and body what it might need. My labs say everything is at the right level. Along the way, I added low-dose Naltrexone, which definitely helped a little (like 1 mg before bed) — it’s used off-label as all-over anti-inflammation drug. That one has stuck. Other exotic ideas my shrink tried, like carbamazepine for a few weeks, and clonidine for another few weeks, did not. In a way, what’s happened this year has been a success. I got down to 75 mg in late summer and was still functioning and far less stressed out— I have never come anywhere close to doing that before. But I can’t cut more than 75. Because ever since hitting this level — where I’m still at — I’m also feeling a bit sluggish and low energy and forgetful and sometimes unmotivated. Those are all symptoms, to me, of not quite enough Wellbutrin. Basically, I’ve traded some problems for other problems, and I can't continue to accept these problems because I don't want to endanger my job. Here’s the really frustrating part: There are times when I start a new drug, or sometimes when I initially increase my dosage of Wellbutrin, when I’ll feel FANTASTIC. Like utterly fantastic and alive and confident and happy and social and productive and like myself — or at least who I want to be. This happened most keenly when starting the low-dose Naltrexone, and it stuck with me for 3 incredible days …and then, invariably, those feelings will slip away. And that’s a horrible feeling, like the guy in Flowers for Algernon. I’m teased with being in this light, that feeling being whole and mentally healthy is actually possible if only my brain has the right combination … then I slip back down into the clouds again. So here I am. A year later, ready to surrender and bump up Wellbutrin back to maybe 100 or 125 and be kinda-okay-but-not-really. Ultimately I don't care if I'm on a drug or off a drug, I just want to be happy and side-effect free, like everybody else wants on these boards I guess. Maybe it's hopeless. But I've tried so hard -- reading and researching and experimenting over the years. I figured I would post here in case there’s anybody who has any thoughts about my case, anything I should do that I’m not doing. I was planning, after triumphantly beating Wellbutrin, posting something on these boards about how I did it. I wish I could write that post instead. But maybe there’s somebody like me out there who has and knows some clue to solving my decades-long brain puzzle. Thank you for reading.
  25. Hello, After some really unsettling stuff and suicidal ideation, I came off of Luvox and Wellbutrin XL under care of my psychiatrist. I hadn’t been on the Luvox very long and my last dose was Jan 3rd. I had been on Wellbutrin XL 300mg for 4+ years and tapered off with my last dose on Jan 12th. Again, I am under a doctor’s care and have regular appointments to check-in, but she wasn’t able to give much information about some weird possible side effects or any time time other than “it should hopefully get better soon.” After the luvox, I had nausea and other intense GI symptoms, but they kind of reared their ugly head and then faded. Possibly because I was on it for so long, but I’m really struggling coming off the Wellbutrin which I though was supposed to have less withdrawal. Last week at the peak of feeling bad, I couldn’t even go into work. I had intense migraines, vertigo, and nausea, spent two days pretty much in bed just trying not to move with a sleep mask on. I also had acute joint pain, not 100% sure that it was caused by discontinuing the meds but the timeline fits, felt like I had aged 20 years overnight with pain in my hands (couldn’t open jars), feet, and knees. Now I’m more than a week out and still with near continuous nausea and dizziness, headaches better than the raging migraines but still there on and off. I also feel like I am just uncomfortable all the time, just feel disconnected like my body is in the way of itself if that makes sense, trouble falling asleep no matter how tired I am because nothing is comfortable. I also felt really weak over the weekend, just couldn’t do normal activities like I had no strength and then was fatigued. My doctor said that since some antidepressants are used to treat fibromyalgia (something I’ve never had before), people can get rebound fibromyalgia symptoms when they discontinue them? Please share your experiences. How long will this last? I feel better mentally, no more intrusive thoughts and so much less foggy, but feel too crappy physically to do much - so frustrating! The headaches, nausea, and dizziness I’m not too surprised about, just really hoping they go away. The weakness and ashiness and just constant discomfort, that was not expected. I keep thinking it’s not the meds, but not sure what else could have changed to bring on such a seemingly drastic change in how I feel physically. What the heck is going on with that? Has anyone else had that happen? When did it finally go away and was there anything you found that helped in the meantime? Again, I am seeing my psychiatrist but I'm concerned about all this because I'm struggling with these symptoms at work (missed days and trouble getting through long shifts) and especially as a mother to a young son. Please help - thanks!!!
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