Jump to content
CrazyBoards.org

Recommended Posts

After trying Invega, Geodon and Abilify with terrible results, my doc put me on Latuda. I'm on day one and the only side effect is my jaw is tight and I was a little anxious(socially) earlier today. This is a huge difference as far as the previous meds as the nasty side effects were immediate and didn't subside even after a few weeks.

Can you tell me your experiences as far as weight gain...sexual side effects...drowsiness...flat affect?

Thanks so much!

Share this post


Link to post
Share on other sites

I only noticed some nausea and drowsiness but it goes away after a couple weeks

Share this post


Link to post
Share on other sites

I stopped abilify and started latuda about 3 months ago. My anxiety completely evaporated in a day or two. However i had horrible vivid dreams. They are no longer crazy and horrible but still very vivid. I also had restless legs and didnt sleep more then a few hours a night for a couple of weeks but that has gone away completely.

I had some nausea too when i first started but i took it at bed time so usually i could fall asleep before that kicked in. I actually lost a little weight since starting it.

Reading this now it seems like a lot of side effects but the benefit far outweighed the cost. And like i said they all subsided realtivly quick.

Good luck.

Share this post


Link to post
Share on other sites

Thank you! Those are side effects that are doable especially if they're temporary.

I agree the benefits outweigh the costs. I came home with a smile on my face today so that was nice lol. Abilify took my personality away!

Share this post


Link to post
Share on other sites

I took Latuda for quite awhile and the only thing I noticed for most of it was a little trouble swallowing. Not like choking, but I had to take a drink every few bites. It wasn't really noticeable, not really a big deal. Unfortunately it also gave me neuropathy which is extremely rare, so I wouldn't worry about that.

Share this post


Link to post
Share on other sites

I've been on it for 7 and a half months now. Same as the others, I got drowsy an hour after taking it, but that went away eventually, and in the first month I was very nauseous and I almost quit, but it went away too. I did not get a flat affect, whereas I did with the other 5 antipsychotics I have tried. I finally went back to college, and my job requires me to think a lot, and I'm fine...also have my same interests. No sexual side effects. It technically didn't boost my sex drive, but after getting on Latuda it improved because I wasn't psychotic and depressed anymore. Best antipsychotic I've ever taken.

Share this post


Link to post
Share on other sites

Thank you so much!

I'm on day two and did really well when I took it last night. A little nauseous and sleepy but that only lasted about an hour. I slept well and woke up well.

Right now, I am so excited to have potentially found the one lol. It's been a rough ride the last few months. I feel like I wasn't myself.

Share this post


Link to post
Share on other sites

How is the Latuda now? Lately I've been worried I got placebos (obviously isn't true but the thought has crossed my mind) because I feel fine but also haven't had any side effects from it lately. Hopefully that means I have grown into the med lol.

Share this post


Link to post
Share on other sites

I've not really had any side effects.

I still have some irritability and intrusive thoughts so maybe I just need to increase the dose.

I go back to the doc in over a week so I'll see about raising it then.

The lack of side effects made me wonder also lol.

Share this post


Link to post
Share on other sites

That's good to hear, but really, it's weird how much food affects it. Except for Geodon I don't think I've ever taken another med that required it. I suppose if we feel better it's working. And actually, think how depressing it is that it's "weird" that it doesn't have side effects. I mean, we've all gotten used to side effects coming along with meds, unfortunately. But as technology increases, medications will get better I hope? Hopefully an increase will work for you; I really love this med.

Share this post


Link to post
Share on other sites

On latuda I had really bad restless legs and some mouth movements. It made me tired about an hour after taking it. I would wake up in the middle of the night but could fall back asleep just fine. I would sometimes have anxiety attacks and psychosis not sure if the anxiety caused the psychosis or vice versa. I would sometimes go 2 weeks at a time without hearing voices followed by 2 weeks where I did hear voices. Latuda was a mixed bag for me.

Share this post


Link to post
Share on other sites

I've noticed some breakthrough intrusive thoughts this week. I'm wondering if I need to go up to 80mg and see how that goes.

Other than the intrusive thoughts and a little irratibility, I've not had many side effects. Well, I've noticed a little less drive to do things but I may need to boost my wellbutrin because I've been on the same dose for 2 years which as some of you may know, it loses effect.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

Sign in to follow this  

  • Similar Content

    • By icygrave
      Hello everyone, I hope everyone's December has been off to a good start. I am back, on the med merry-go-round and also sober from opiates.... Again (16 days as of now).
      So I was taking wellbutrin as an add on to my Prozac, and it really didn't help and might have made me worse, losing dramatic amounts of weight, a lot of intrusive thoughts, very depressed (though that's probably just it not doing much for it. And getting off drugs.) so I'm now on the Rexulti starter pack.
      I'm here seeking others experiences with abilify and rexulti, since they are both dopamine partial agonists and 5-ht1a partial agonists, amongst other things. I'm very nervous about taking an antipsychotic for depression, though... And just want to know of other's experiences starting these medications. How were the side effects? If you had any, did they eventually go away? Did you gain weight?
      I appreciate anyone who shares their experience. I've asked about these meds before, but I'm so nervous about it I just want reassurance. A lot is changing around me. Thank you all so much, and I hope the holidays have been treating you well.
    • By Truthometer
      Abilify (Aripriprazole) is a partial agonist on dopamine receptors with 60% the activity of dopamine on receiving neurons and 75% activity of dopamine on firing neurons [1].  Abilify is the only antipsychotic which can increase dopaminergic activity in the mesocortical pathway through dopamine partial agonism. Abilify is a 5HT1A partial agonist (68%), which causes dopamine levels to go up in the prefrontal cortex. Abilify is also a 5HT2A antagonist; which has antipsychotic and antimanic properties [2].

      Here are the Four Dopaminergic Pathways and Abilify's Effect on them
      1. Mesolimbic (Abilify decreases activity)
      2. Mesocortical (Abilify increases activity)
      3. Nigrostriatal (Abilify dampens down)
      4. Tuberoinfundibular (Abilify does not cause prolactin release unlike dopamine antagonist antipsychotics. In fact, even low doses of Abilify can reduce prolactin release caused by dopamine blockers). 
      Abilify reduces neurotransmission in three of the four dopaminergic neuronal pathways. 

    • By Truthometer
      Aripriprazole: Intrinsic activity = 60% on post-synaptic D2 ; up to 75% on pre- synaptic D2 receptors.[1]
      Brexiprazole: Intrinsic activity = Up to 46% [2]
      Cariprazine: Intrinsic activity = Up to 71% [3]
      Aripriprazole is a partial agonist with functionally antagonist activity on receiving neurons and functionally agonist activity on firing neurons; both of which dampen down dopaminergic neurotransmission. Aripriprazole can increase dopaminergic activity in the mesocortical pathway, unlike dopamine blockers, Aripriprazole partially agonizes D2, D3, 5HT1A and to a lesser extent D4 receptors; antagonist at 5HT2A, as other atytpical antipsychotics.[1]
      Brexpiprazole has more blocking and less stimulating activity at the dopamine receptors than its predecessor, aripiprazole, which may decrease its risk for agitation and restlessness. Specifically, where Aripiprazole has an intrinsic activity or agonist effect at the D 2 receptor of 60%+, Brexpiprazole has an intrinsic activity at the same receptor of about 45%. [2] 
      Cariprazine is a dopamine D2- and D3-receptor partial agonist, with higher affinity for D3 receptors, as opposed to the D2antagonism of most older antipsychotic agents.Cariprazine has lower intrinsic activity at D 2 receptors than aripiprazole. Its intrinsic activity is up to 71% [3 ] 
       
    • By NerdyUnicorn
      I recently got increased on my Latuda for some mixed symptoms - I'd been on 60mg one night and 80mg the next to even out at 70mg overall and we went up to just straight 80mg, so not a large increase. I've been stable for a long time, so it's been a while since I've really had to change anything. This morning I'm noticing some cognitive symptoms, which are definitely not fun. Trouble reading and thinking, mostly. 
      I'm wondering how long it usually takes you to adjust to a new dosage in terms of side effects - if you have experience with Latuda, great, or just in general. I remember whole new meds take a month or longer but I don't really remember how long just dose increases take. 
    • By icygrave
      I was curious about Abilify, first off have you personally seen a huge increase in weight after getting on abilify? I hardly have an appetite, even without meds, and it's very hard for me to gain weight. I also exercise pretty modestly, about an hour a day. Would I be safe from weight gain caused by Abilify? The only antipsychotic I've been on long term was Seroquel, helped me a lot and I don't think I gained more than 10 pounds, which could've just been me not being so depressed and having an appetite again. Is the same likely for Abilify? I am just terrified of this because I have gained a large amount of weight, over 20 pounds from one medication which was Remeron. It really messed with my body and I am terrified of that happening again, because honestly, being fat makes me feel ugly and even more depressed.
      Second, I wanted to talk about something my   psych brought up to me. He said that Abilify and it's relative Rexulti, have "pro-cognitive" effects, meaning they help with brain fog, apathy, concentration, motivation, and even energy. Apparently both are used for ADHD, with even the makers of Rexulti trying to get it approved for ADHD. Have any of your experienced this from either of the two? Because I am in need of something that helps with cognition, mainly apathy and low, low motivation and interest.
      Bottom line, I am very interested in Abilify and its sister Rexulti. They are very interesting pharmacologically, with them being sort of unique antipsychotics... I would be taking Abilify for depression and as an add on to an antidepressant, by the way. I've always been scared of the word "antipsychotic" but knowing how Seroquel basically annihilated my depression in the past, I can't deny their benefits. Please share your experience, and as always, thanks for helping me out.
×