Sign in to follow this  
Followers 0
vandeeje

What was/is your therapeutic dose of Effexor ER (venlafaxine ER)?

11 posts in this topic

I'm going to see my pdoc on Wednesday and right now I'm only on 75mg of venlafaxine ER (Effexor ER) and still really struggling with depression. That's putting it lightly. I spend 14-18 hours a day in bed, I rarely eat, my motivation and concentration are shot...let's just say it's not good. And I know what you're thinking, I should have called my pdoc about this already, and I did. The nurse said to wait until I see him on Wednesday to bring it up. I know what you're thinking now, my pdoc's office is full of assholes, and you're right. I am seeing a new one at the end of next month.

Anyway, I'm wondering what dose people have found therapeutic (of the Effexor ER)? I want to ask my pdoc to double my dose and am wondering if I should ask if that doesn't work if I can just call and have it upped again without having to fight with the nurse. Does that make sense?

Share this post


Link to post
Share on other sites

I went up to 150 mg. Did nothing to lift my depression in those times. I took it for 6 months and then simply drop it. Curiously enough, without any tapering at all and I did not get any withdrawals. I am not endorsing this irresponsible behaviour, though.... YMMV.

Share this post


Link to post
Share on other sites

When I took it, I believe that I was up to at least 300 mg of the immediate release (75 mg 4 x per day).

Share this post


Link to post
Share on other sites

It was never fully effective for me, but I was an extremely depressed 15 year old. I think I did best on 225mg/day. We did try to go up further but I got too jittery at 300mg. From reading people's signitures on here it looks like most people take 150mg+. Sorry to hear you're feeling so shitty. I hope this works for ya.

Share this post


Link to post
Share on other sites

It did not become effective for me intil I hit 300mg. Unfortunately that was also the dose that sent me into mania

Share this post


Link to post
Share on other sites

300mg had me hypo, so 150 worked best..

Share this post


Link to post
Share on other sites

Weirdly, I could only tolerate the base dose (75mg) of extended release of Effexor, any higher and I felt sick, so I just stayed on the base dose for years.

I then moved onto its cousin Pristiq and stayed on the base dose of that (50mgs) for years. It did help with my depression at that dose, but would probably have been more effective at a higher dose, but my then Shrink never pushed me to go higher.

My current Shrink has gotten me to withdraw off Pristiq due to his feeling that at the base dose it was below therapeutic levels. I'm not convinced that's the case though, as I felt that even at the lowest dose, both Effexor & Pristiq did have an effect.

Sorry for the rambling, to cut a long story short, YMMV

Share this post


Link to post
Share on other sites

I take 37.5mg every 3 days. I'm really sensitive to it. I take it when I start to feel the depressive part of my BP start to creep in. It zaps me out of wanting to wallow and sleep all day. Plus only taking it every three days allows for me to avoid sexual side effects. Working so far...

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
Sign in to follow this  
Followers 0

  • Similar Content

    • By Sleeeeeep77
      I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream🎃
       
       
    • By Sleeeeeep77
      I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream🎃
       
       
    • By Sleeeeeep77
      I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream🎃
       
       
    • By buckeye74
      I have run the gammit for SNRI/SRIs in the last 18 years. Most I cannot tolerate. A year ago I started Lamictal for treatment resistant depression. I have depression and generalized anxiety. The Lamictal initially worked great for both! However, about 6 months into it my anxiety resurfaced. The anxiety is so bad that I have trouble driving/riding on the highway because I'm afraid we're going to have a terrible accident. I am in constant fear that something bad will happen to my loved ones or my pets. I have to check everything in my home 2-3 times because I'm terrified my house will be broken into. I've started exhibiting signs of OCD. I am in therapy. Since starting the Lamictal, I've tried Lexapro (nonstop headaches for 2 weeks that I just couldn't take it anymore), Neurontin (didn't work at all), Lyrica (up to 100 mg now-takes the edge off but not completely), Seroquel (made me so angry-like a total personality change and felt pressure in my chest) and propranolol (did nothing). My neurologist had suggested going back on Effexor for my migraine headaches. I took it for 9 months but it seemed to exacerbate my anxiety. I'm currently on 200 mg of Lamictal. 
      I am super frustrated! I feel like my pshychiatrist is throwing meds at me & she's more or less told me we don't have a lot of options left and talked about compounds of Klonipin or herbal remedies. 
      I guess my question is: should I start over from scratch? I've read others comments that said Lamictal caused them to have anxiety. Lamictal works for my depression but my anxiety tends to depress me because it just wears me out and I feel at the end of my rope! Or is there something else I can add? 
      Ive tried:
      Zoloft, Paxil, Wellbutrin, Cymbalta, Lyrica, Neurontin, Seroquel, Propanolol, Lexapro, Effexor
      Please give me your thoughts! 
       
    • By 0112358
      I took Effexor for one day and experienced horrible side effects - vomiting, sweating, nausea, shaking, sleepiness. That was three days ago, but since then I've been sleeping all the time and am still shaky. Has anyone else experienced something like this after only one dose?