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My doctor lowered my dosage of Seroquel and I had just gotten a refill a week ago and it will save me a lot of money and stress to just cut the pills in half (he lowered it to half the dosage I have now). I know you're typically not supposed to cut extended release tablets in half, but is it dangerous? Has anyone done this? It seems like such a waste, I have 60 pills in this bottle. 

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Someone else here might be able to give you a more scientific answer, but in my opinion it's not worth the risk.  Extended release tablets generally have a special coating, which you'll break if you split it.  I think the risk then is that you'll get the full dose all at once and completely lose the XR feature (and presumably your pdoc had a reason for prescribing XR instead of instant release). 

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It's not really dangerous but still it would be better to get a refill. If you take split pills, it may not last for as long as your pdoc intended.

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Hmm, he cut the dosage in half and switched it to IR, actually. I don't know if that changes anything. I'm probably just going to end up getting the new meds in a couple weeks and I'm wondering if I should take the whole pill or just cut it in half to get myself started. I guess its just best to suck it up and wait, though. Thanks for the responses, guys.

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Ask if its ok to finish the old pills.   Cutting extended relief pills is a bad idea.  If I understand this it will give you a days worth all at once and you don't want the all at once dose or the nothing you'll get for the next 23 hours. 

 

*P.S. don't sweat the waste of the pills.  I hate to tell you how many most of us have collected and tossed trying to find the right one(s)    Its ok!   Really...

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Yeah, I've thrown out meds I had switched from before but it seems wasteful since I just filled them.  <_<  Oh well. I think I can cover it, I'll just take the old amount until then.

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Cutting the XR pills won't give you an equal dose in each half.  One half could be all with the other nothing, or one pill 30% and the other 70%, etc.  If your body is used to the XR, the amount given in each half could be too much at once.

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I've snapped them in half a few times I suffered no ill effects, you might get more of the dose more quickly, blood levels may fluctuate.

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