Sign in to follow this  
Followers 0
radicalfeminist

Seroquel XR - Can I cut it in half?

8 posts in this topic

My doctor lowered my dosage of Seroquel and I had just gotten a refill a week ago and it will save me a lot of money and stress to just cut the pills in half (he lowered it to half the dosage I have now). I know you're typically not supposed to cut extended release tablets in half, but is it dangerous? Has anyone done this? It seems like such a waste, I have 60 pills in this bottle. 

Share this post


Link to post
Share on other sites

Someone else here might be able to give you a more scientific answer, but in my opinion it's not worth the risk.  Extended release tablets generally have a special coating, which you'll break if you split it.  I think the risk then is that you'll get the full dose all at once and completely lose the XR feature (and presumably your pdoc had a reason for prescribing XR instead of instant release). 

Share this post


Link to post
Share on other sites

It's not really dangerous but still it would be better to get a refill. If you take split pills, it may not last for as long as your pdoc intended.

Share this post


Link to post
Share on other sites

Hmm, he cut the dosage in half and switched it to IR, actually. I don't know if that changes anything. I'm probably just going to end up getting the new meds in a couple weeks and I'm wondering if I should take the whole pill or just cut it in half to get myself started. I guess its just best to suck it up and wait, though. Thanks for the responses, guys.

Share this post


Link to post
Share on other sites

Ask if its ok to finish the old pills.   Cutting extended relief pills is a bad idea.  If I understand this it will give you a days worth all at once and you don't want the all at once dose or the nothing you'll get for the next 23 hours. 

 

*P.S. don't sweat the waste of the pills.  I hate to tell you how many most of us have collected and tossed trying to find the right one(s)    Its ok!   Really...

Share this post


Link to post
Share on other sites

Yeah, I've thrown out meds I had switched from before but it seems wasteful since I just filled them.  <_<  Oh well. I think I can cover it, I'll just take the old amount until then.

Share this post


Link to post
Share on other sites

Cutting the XR pills won't give you an equal dose in each half.  One half could be all with the other nothing, or one pill 30% and the other 70%, etc.  If your body is used to the XR, the amount given in each half could be too much at once.

Share this post


Link to post
Share on other sites

I've snapped them in half a few times I suffered no ill effects, you might get more of the dose more quickly, blood levels may fluctuate.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
Sign in to follow this  
Followers 0

  • Similar Content

    • By Paige17
      Hi all, my Pdoc switched me from 25mg Seroquel XR to Zeldox 40mg last week due to weight gain. Have been diagnosed with Clychothymia (Bipolar 3) and Major Depressive Disorder.
      Gained so fast on Seroquel XR over six months I have stretch marks for the first time in my life, though I did not put on an insane amount of weight. Tapered off Seroquel over 3 days, and had no problems. But have been experiencing intense(!!!) nausea on Zeldox every day this week, It doesn't matter when or how I take it - an hour before bed with/without food or during dinner - everything I ate during the day comes right back out and I have a nasty lump in my throat feeling until I wake the next morning. On my 2nd night on it I thought I was going blind - lights were intense, couldn't walk straight, or focus on a thing. Had what felt like a panic attack and forced myself to sleep. Since then, I've reduced my dose to 20mg as advised by Pdoc but am still ridiculously nauseous to the point of vomiting. My social anxiety and insomnia is back with a vengeance. Aside from the weight gain, I had 0 side effects from Seroquel and felt fantastic for months.The only upside to Zeldox is a significant decrease in appetite - I literally have to force myself to eat but that's possibly just the damn nausea.
      My question to those with experience : at this point, would you give Zeldox another week? Go back to Seroquel and diet your ass off? Or try a different anti-psychotic like Ablify?
       
       
    • By Light
      I've been on Seroquel( well generic, Quetiapine ) for months now, i've been on 100mg at night - Since its been amazing for helping me sleep at night, i have noticed my anxiety hasnt really improved ( not blaming meds ) and my moods have not either, infact im up and down in some type of pattern ( noticed a week or 2 weeks before im due for my period ) i seem to get suicidal and/or really depressed ) - anyways im going off topic a little -
      Wanting to not be sleeping my days away i thought id go back to GP and tell him, i told him i really dont wanna change meds ( because this is my first time being on Antipsych meds ) and i was scared enough as it is going on them in the first place - anyways, he said for me to take 100 mg in the morning and see how that goes - oh boy was i wrong in feeling like that would help..
      I was doing that dosage for 3 days, those days were all fine, infact i was feeling really drugged up and relaxed ( i took that as a good sign that that would start working in a week or so ) - Hell no, no no no no - Its been 7 days since i had light headed and HUGE panic attack that is just worse, i got up to get a drink from being on pc and i though oh wow this is weird i dont feel good, its like a panic attack but worse, walking around i thought fuck im going to passout, yup im going to pass out and im gone, something felt so so wrong, anyways not a good time i nearly had to get my mum to call ambo, she really wanted me to but i freak out, im scared oh hospitals (aswell as ending up in psych ward, great fear ) - anyways to cut it short, 2 doctors later and im on day 7, i feel not well at all still. After this happened i went back to my 100mg dosage at night only ( 2nd doc that i had to call to home ( home doc ) said to do that, 1st doc i went to was really useless ( Sunday doc, my doc was shut ) - I still feel like walking around and even sitting down like im going to pass out and panic attacks/anxiety attacks, the main thing is i feel like im " not here" its scary as fuck and i want it to go away, its horrible its hell. Does anyone have a clue or something happened to them going up in dosage on Seroquel/Quetiapine ?
      Both doctors didnt give much - And yes im going to go see a pdoc, its just really hard atm, im really struggling, i wanna feel like myself again, i want these passing out/ not feeling like im here that i get with panic attacks to go away, i thought by now id be better since im on my normal dose again and its been days, and im doing my best to stay as calm as possible and not freak out as i read thats not going to make it better. Also have freaked myself out at reading another forum and people have this and its lasted them a month/ or months or even years, im so scared and im so so tired, its draining, i feel like im always on the couch now, so instead of sleeping my days away im now couch bound and feeling like this..
      I've been meaning to make this thread for days now, i keep holding hope that its going to go away
      I hope i havent forgotten  anything and sorry about typing or any errors as my mind is just really all over the place confuses slightly
      It might not even be from the upped dose? I dont know. I thought maybe its from something else, since i have been have nightmares ( meds make them vivid but then again i have dreams that are vivid so im not blaming meds ) and it has been bringing someone up but i wont get into that as its very TW im sure to others, and it might not even have anything to do with that.
    • By Swamp56
      I've been on Seroquel continuously for the past 4.5 years in doses varying from 300mg to 600mg. Due to side effects and questionable efficacy for the past year or so, my pdoc and I decided that a switch in meds is warranted. She's had a lot of success with Saphris and we've decided to give it a try. To ease with withdrawal, we chose a 2-ish month transition state where my Seroquel will be waned down by about 50-75mg a week and Saphris will be increased every 2-3 weeks (2.5mg -> 5mg -> 10mg -> 20mg) depending on how I feel. It's been about two weeks now (450mg Seroquel & 5mg Saphris) and I'm noticing transient akathisia and I also feel a lot flatter. This is the first time I've ever had to switch a long-term medication like this, and I'm not sure what to expect, and whether things like flatness are common. For those of you who made switches from long term use of an AAP, how did it go for you? What sort of side effects did you notice?
      Thanks!
    • By Swamp56
      Hello everyone :), it's been a long time since I've posted here and I hope everyone is doing well.
      I've been taking Seroquel for a little over 4 years now, with doses ranging from 300mg - 600mg. I noticed that there's a relatively predictable sequence of events after I take my dose that disband after about an hour; my doctor has me take a single dose near bedtime. First, I notice an almost indescribable heavy/cold feeling behind my eyes and under my skin. This is always accompanied by fatigue and, sometimes, an out-of-breath feeling when I stand up. I also notice that my mood and anxiety levels go out of whack. I feel dysphoric and my anxiety goes through the roof. About an hour after my body starts processing the medicine, all of this alleviates and doesn't resurface until I take my next dose. Has anyone experienced something like this before? I've brought it up with my pdoc but she hasn't really had anything to say other than I can try switching medications.
    • By dragonfly23
      My meds are listed below.  Recently, maybe the last few months I seem to be covered with bruises. I dont know where they come from.  (well some I do, I  am a klutz which I blame on seroquel ) Some dont hurt at all and others are painful.  
      It's getting sorta ridiculous.  I see my Pdoc on Wednesday and will bring it to his attention.  Maybe some blood work is in order. 
      Has anybody experienced the same?  Was it med induced or other health issue induced?