Sign in to follow this  
Followers 0
CookieN

MOOD STABILIZERS, do they really help with mood swings?

27 posts in this topic

When you started Mood Stabilizers, did they really help with your mood swings. Did they really lessen your mood changes?.

 

Do you have any experience with the following meds: Lamictal or Topamax?

 

Does the efficacy decrease as time goes by? meaning that mood stabilizer could really help at the beginning but then lose its efficacy?

 

Do you feel traditional mood stabilizers, work better in controlling moods than antipsychotics (when they are used as mood stabilizers). I am taking zyprexa as a mood stabilizer

Edited by CookieN

Share this post


Link to post
Share on other sites

I've had a lot of success with a combination of Lamictal and lithium recently. I've only been on them for 7? months now, so I don't know about long term loss of efficacy. It's really leveled me out without any flattening of affect. I have had to make some small adjustments, though. I started getting a bit hypomanic about a month ago, upped my lithium a little and it put the brakes on. Now back to stable.

 

I happen to love the Lamictal. No noticeable side effects from that or my lithium. But everyone's pharmacology is different, YMMV and all that. No experience with Topamax.

 

Edit (in light of your edit): Yes. Very yes. I've never had a good experience with antipsychotics. Again, YMMV. I know they help some people. But I'm really not a fan of how atypicals have become so standard as mood stabilizers when there are plenty of tried-and-true actual mood stabilizers out there, generally with less side effects.

Edited by misanthropicusername

Share this post


Link to post
Share on other sites

goodness yes they help

that is why we take them!!

 

I think it is very individual whether you take an AAP. an AC, or a combination of them

Lamictal seems to be a workhorse for depression

 

and Lithium is both anti manic, plus helps with depression

Share this post


Link to post
Share on other sites

"Does the efficacy decrease as time goes by? meaning that mood
stabilizer could really help at the beginning but then lose its
efficacy?"

 

 

I am on lamictal and haven't had this problem.  I've been on 600 mg for many years (at least 10 years, probably more).

Share this post


Link to post
Share on other sites

I turned out to have an allergic-like reaction to lamotrigine, so, none of that for me.

 

The second they tried with me, divalproex sodium (Depakote/Epival,) works like a charm, at the right dose.  It acts as an antidepressant for me, which is usually my main problem.

 

I can apparently have breakthrough symptoms/episodes, as my recent mixed state over this past month demonstrated.  But apparently this is not too unusual and commonly related to things like seasonal changes, for example.  Yay for spring!  I then required additional medication therapy while IP for about a week to get the hypomania end of my mixed episode under control.  They used a combination of clonazepam, quetiapine, and Zopiclone, along with my regular daily dose of divalproex -- and they took me off my Concerta just for the duration.

 

I'm back on the Concerta again, clonazepam has been in my little collection for a while for anxiety issues, still on divalproex and now I have Zopiclone for sleep issues which can crop up for me time and again - not necessarily related to the bipolar, hell, my ADHD makes staying up allll too easy.

 

I also have quetiapine added into my cocktail now.  It's supposed to be a PRN like my clonazepam and Zopiclone, but I've been having success with it as a daily med... not for my bipolar, really, but more for some of my OCD-related things and dermatillomania.  I'll be speaking with my pdoc about her thoughts on this during our next appointment.

 

I am comforted by the thought that if it ever turns out that my divalproex *does* become less effective, I have lots and lots of room to go up on the dose.  Both in terms of how much I take per day and in blood levels (I'm at the lowest end of 'effective blood level' for valproates, upon blood testing.)



*** oh, and it took about a year for me to have a breakthrough mixed episode after we got me on the divalproex.  And after about two weeks of treatment for it I seem to be getting back to normal.

Share this post


Link to post
Share on other sites

I started Lamictal (Generic) after Abilify was making me unable to sit still. It has been very good to me as a mood stabalizer. I still get moody and itritable and depressed but its no longer from A to Z depressed. I get some minor breakthrough but I manage that with therapy.   The swings are more A-C anoying but managable for me. A gloryaus wonderfull change from this point last year when every day felt like a A-Z mess.  I was a mess during tiration becuse we where still trying to figure it all out, but it has been worth it for me. I do have some GI issues but I do not know what med it is (but i'm looking at you Celexa, i'm looking at you. But maybe you and the Metformin are in cahoots...)

 

I tried topomax for about a week and it made me physicly ill to the point that I could not take it. But it might work for you.

Share this post


Link to post
Share on other sites

Thank your for your responses!......For those of you who are taking Lamictal and Depakote....did you gain weight on them?

Share this post


Link to post
Share on other sites

No weight gain on lamictal.

Share this post


Link to post
Share on other sites

I've actually been slowly losing weight since I started Lamictal. Which is good, I could stand to lose a few lbs.

Share this post


Link to post
Share on other sites

I love Lamictal.  I've been on it for about four years, with no change in efficiacy and no weight gain.  I had some headaches when I titrated up, but they went away after a couple of days, and were controllable with advil. 

Share this post


Link to post
Share on other sites

I gained a buttload on depakote but i love lamictals lack of side effects.

Share this post


Link to post
Share on other sites

No weight gain on the Depakote for me. *shrugs*

Share this post


Link to post
Share on other sites

I like my Lamictal. It worked better for me than Abilify but not as good as Seroquel.

Share this post


Link to post
Share on other sites

No weight gain on Lamical or Depakote, but I did lose a lot of hair at a high dose of Depakote (3000 mg/day).

Share this post


Link to post
Share on other sites

I was on lamictal(100 - 200mg)  for 4 years before it lost its efficacy and started causing side effects. But my pdoc suggested going back on it again recently, if the viibryd he prescribed didn't work for depression.

Share this post


Link to post
Share on other sites

No weight gain on Lamictal, but weight gain on Epilim (SA equivalent of Depakote, well, almost).

Share this post


Link to post
Share on other sites

Moving this to AntiConvulsants.

Share this post


Link to post
Share on other sites

Lamictal certainly did lessen my mood changes. I didn't gain any weight on it either. I'd highly recommend it.

Share this post


Link to post
Share on other sites

I'm on 400Mg lamictal and no side effects. Well, I do have some problems with word finding but not enough to go off it and I really don't want to lower my dose cause it's working well.

Yes I still have breakthrough depression at time and one breakthrough mania but both only lasted about 4-6 days and I just worked through it and have been pretty fine for quite some time.

I also like Seroquel for sleep and I guess at my dose it works for depression as well. No side effects from that either, no weight gain.

HTH

Share this post


Link to post
Share on other sites

I had some crazy side-effects from Lamictal + AAPs, but they all subsided. I tried Lamictal as a monotherapy, but it did almost nothing for my depression. No weight gain.

Valproate hyped me up and killed my memory. I wasn't on it very long, maybe 6 weeks, but no weight gain from it either.

Share this post


Link to post
Share on other sites

I gained 40 lbs on Depakote....pretty common, plus a tremor, my hair started falling out, and my liver numbers were bad

the side effects were terrible and my doctor refused to let me try something else..

I was on a high dose for four years

fortunately I got a different doctor and went onto Lithium

 

 

Lamictal is supposed to be weight neutral....I have not tried it yet

Edited by bpladybug

Share this post


Link to post
Share on other sites

Thank you again for your responses. I am glad to know that most of you didn´t gain weight on lamictal

Share this post


Link to post
Share on other sites

I have tried so many different meds and have had all kinds of side effects. I am on lamictal and I really like it. I actually lost weight on it and I haven't been manic since I've been on it. It also really helps my depression. It's the best med I have tried.

Share this post


Link to post
Share on other sites

I take Lithium and Lamictal and have had no problems with weight with either of them. I did with Depakote though

Share this post


Link to post
Share on other sites

Depakote totally flattened me out and made me sleep all day. This was however years before I had the diagnosis of bipolar disorder.

When the diagnosis came I was put immediately on Abilify and it did wonders for my mood swings; only for my regular day to day mood swings and hypomania.

It didn't help for depression though so I came off as I've been depressed for ages now and I'm hoping that I'll switch soon to hypomania.

 

Nevertheless looks like a lot of people have good experience with lamictal so I could promose that to my doc if he really wants to put me on some mood stabilizer again.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
Sign in to follow this  
Followers 0

  • Similar Content

    • By katkatkat
      Hey guys 
      So I started Latuda about 8 weeks ago at 20 mg, (just the starting dose but wasnt able to get into see my doc when I was supposed to) I am definitely feeling some effects, most of them good, but I wanted to know if anyone has experienced or heard of the same? 
       
      -Weight loss. I've always been about 100 lbs, super "skinny", always get asked if I eat blah blah blah. If you're a naturally skinny girl with "a fast metabolism" you understand... Now I've NEVER been under 100 pounds (even when I never eat) but now I have been consistently eating A LOT more and my weight is dropping quickly. I was 96 pounds about two weeks after starting Latuda and I'm now at 90. Need to ask my doc but anyone experience? 
      -Insomnia. what I've noticed is that even if I get to bed really late, if it is before 5AM, I'll wake up at early 9/10. Usually, if I went to bed that late, I would sleep all day. I know, my sleep routine sucks. *I STARTED TAKING IT IN THE MORNING AND THIS HELPED 100% with sleep* I now sleep like a baby and am naturally tired by the time 10pm rolls around I actually like waking up at a decent time and starting my day, something I've never even thought was possible before this drug.
      - I am popping up all the time to get things, or move things, or do things for others in my house(like getting my boyfriends a drink from downstairs anytime he asked without whining about it first).. I think this is just me starting to feel better, but am open to different interpretations
       
      -On the whole, I am beginning to feel pretty good, but not that "I feel soooooo good," hypomania. But I do get really irritable for about 15 minutes a few times a day.
       If anyone can relate, knows if this is normal or if anyone thinks something is off, could you please give me your opinion?
       
    • By Vesse
      So the story is really complicated but I don't know how to move on with my life after it.
      To summarize, I got married 4.5 years ago and we moved here together. From the beginning he constantly threatened me with divorce which took its toll on my mood (I tried commiting suicide a few months after moving here). I never wanted to cheat but in addition to threats of divorce, he always called me oversexual and suggested I see a doctor (I wanted sex once a day... not unusual for a guy). Despite all of this I worked hard at a job I hated to support the both of us (he wouldn't work, he was a full time student and could have worked to help me, but he didn't want to do anything not related to his field of study). 
      Anyway, fast forward we got our green cards (from my work that I only stayed at for him). A few months later he started dating (we were trying an open relationship but dating was not supposed to be allowed). He also lost "part" of his virginity to the guy he was dating and who is now his current boyfriend. He went back home to visit for the summer and asked me for a divorce 7000 miles away. We agreed to try and work through it, but meanwhile he was having sex with lots of different guys and he got back here only to mislead me and get me to still pay for his expenses despite being in love with someone else. He claimed "I can't decide about our relationship if I don't have food" so of course I bought him food...
      I'm bipolar and I have tried years and years of medications with no luck. Earlier this year I started smoking meth which I know is not good for you. I minimize the risks as much as possible of course and I can hold my own in an argument about whether it's actually as bad as the media portrays (for example, I know hypertension can cause LVH which is a serious risk factor for things like sudden cardiac death, not to mention aortic dissection and congestive heart failure... I want to be a vet lol).
      So here's the thing, smoking meth helps prevent my suicidal thoughts, but I do want to give it up and start focusing on my future. I need help though. Logically I don't want to be married to him, he's a terrible person (you can't say deep down he's a good person, I left out something very big because it's too painful for now, but I can share if it helps you help me :-( ).
      How can I move on from what he did? I just can't seem to do it. Logic is failing me which really sucks. What has cheered me up lately is accepting the fact that I think I'm done with relationships. I've had it, and I don't want it. You can say I'm jaded, I'm just in shock, or I'll change my mind one day, but it's the only thing that helps me when I'm feeling down. Recognizing that that part of my life is over. I do have a long road ahead of me, vet school (hopefully) but first I have to work about 2 years to save up for it. But despite a great plan, I can't get over it. It doesn't help that he's not cooperating at all with the divorce (which I now want of course). So now I'm filling out the papers and paying for my own divorce... that's really some twisted stuff right there. See? He's not a good person.
      Please help because the suicidal thoughts are stronger than ever. I tried going to a psychiatrist to get on meds again and he said he wouldn't prescribe me anything for at least a few weeks.... I've been on at least 10 bipolar meds and he's making me wait with vivid suicidal thoughts... first, do no harm?
      Can anyone help me please? 
       
    • By Rabidtears
      Well I posted a couple of weeks ago that my doctor was looking into a possible diagnosis between seizures, narcolepsy, and migraines. I am still waiting to see how that goes. 
      Wednesday I had my consult with the sleep clinic which flagged me a lot for narcolepsy, which may or may not be relevant as I know these intermesh a lot with each other.
      I have continued logging all of my seizure like episodes since I've noticed that they were more than just typical chills. If I knew how to link that post I would .The gist is for those who have not read it is it a chill like feeling in the back of my Neck, head and shoulders. My eyes would roll back and eye lids would flutter. Started out lasting roughly 2-3 seconds then progressed over time to 3-5 seconds. There was a cold shiver included with the eye roll and my head would snap backwards.
      As time passed by symptoms slowly progressed. Some nights I would have 5 or 6 back to back, mainly if I were in a vehicle that had wind and ac sometimes none. Seems to be triggered by wind and cool/cold air. I cannot induce it nor does it happen all the time. Afterwards, I am sometimes sick or have aa headache, but I am always sleepy for the rest of the day.
      I have continued to maintain awareness. In the last week or so my arms have begun to jerk upwards during these 'episodes' and shake a touch. Not long. Like I said they only last a couple of seconds.
      Now...the newest thing that would freak me out if I were not on an awesome bipolar regimen that squashes my anxiety.....
      Yesterday I had an epidose. The heat index was about 100 degrees and I was sitting in front of a huge fan trying to stay cool. Hair was pulled up. Next thing I knew my arms, shoulders, neck, and head tensed and jerked. My head snapped back. Eyes rolled. Lids fluttered. I can't remember if I felt the usual cold shiver or not because when my arms jerked upwards I felt a warm tingle that felt like electricity [best way I can describe it] go all the way to my finger tips of both arms. It matched perfectly. It was not painful like neuropathy, not pins and needles, just a warm electrical tingly feeling if that makes sense... I don't know how else to describe it. It started and stopped with the episode. 
       
      Does anyone have any ideas on this???
    • By Eddie_BP1
      Hello,
      This is my first post on this board. I was diagnosed and treated for bipolar 1 from 2002-2015. Last year I went off medication, and have been med free since Oct 2015. I went off because I believed the medication was hurting me more than helping and making me sicker. I felt I had nothing to lose.
      As a result, I regained mental clarity but had one long mania cycle and I am now in a very depressed cycle which is difficult to.endure.
      I am very depressed from stress but mostly from the fact that I now see clearly how my bipolar has wrecked havoc in my life. I am seeing it clearly for the first time and I am accepting it. 
      I am 52, divorced with 3 kids. My oldest doesn't talk to me at all, my middle has some communication, getting better and now my daughter 13 doesnt speak to me. The alienation creates severe feelings of pain for me. I have hurt them and their mother and this is my reality.
      Their mother has played my mental illness against me in the divorce and has sought to alienate me from my children. She has provoked confrontations with me, has had me arreated and has played the victim to the hilt. I now have several court motions to addressential with her on house and alimony and alienation issues.
      There is nothing more painful than not having a relationship with your kids.
      Because of the massive losses, caused mostly by mania, I am now willing to accept treatment for my bipolar again. I am very afraid of medications that sedate me, make me lose my memory and effect my body weight. I do not trust psychiatrists, pharma, or medication. But I need help.
      I am a lost soul right now trying to find my tribe and get direction. 
      My parents are supportive and a few friends but I have lost nearly all my relationships to my craziness and disorder. I had substance abuse problems as well but have been sober now for almost a year.
      I hope to hear from some of you that there is hope, that one can get through massive depression and pain as well as mania and find meaning and purpose in life.
      I really need to connect with people that are managing this illness well and might understand. I am powerless over my bipolar and my life is unmanageable. Thank you.
      Eddie
       
       
    • By Dontspeak
      Hola,
      Has anyone tried BOTH ($30) methylpro and ($58) deplin and have a review of efficacy for each? My pdoc literally just called me and said he's tired making people pay twice the price deplin charges, and wanted me to post, bless his soul.
      Bless my soul I am a mania and mixed episode monster and cannot be the guinea pig for this SSRI booster.
      Gracias