11 posts in this topic
Switching from Seroquel to Latuda
My issue: Bipolar II, severe depression and anxiety, as well as insomnia.
I've been taking Seroquel for about two years. I take 200mg Seroquel in combination with 200mg Lamictal. This combination has worked fairly well for me, so far, in at least alleviating my depression enough to make me functional. I haven't had serious side effects beyond light periods (but those could also be caused by my IUD), gaining like 10 lbs over 2 years, and serious grogginess in the morning that's really hard to shake. I have a lot of trouble getting out of bed and it takes me 2 hours to fully wake up. It also makes me, as my mother describes it, "spacey".
I recently switched to a new psychiatrist and primary physician due to changing jobs and health insurance. I'd been having regular blood tests done, but the new primary doc and psychiatrist didn't like the results of my most recent one (for my kidneys). New psych also seems to really dislike Seroquel and preferred I switch to something different/newer, and wants me to try Latuda. I agreed to do so mainly because the Seroquel doesn't completely help my depression and definitely does not help my anxiety, which has been problematic lately.
I'm having trouble remembering to eat with my Latuda, too, which worries me. From what I understand, it doesn't work as well without food.
For those of you who have switched from Seroquel (or even another atypical) to Latuda, what was your experience like? Was the Latuda better, worse, or neither?
invega 4 yrs. latuda 3 months horrible
By Starry Night1969
Schizophrenia, all the cool kids have it. I had 10 or so of the side effects on invega, max dose and still heard voices and strange ideas. I was capable of doing 5 or so things a day such as eat at mcdonalds or take a 20 min bike ride. My psych tweaked one of 5 scripts a month for 3 yrs but it never worked and finally my dang psych just ordered a blood test. My results were bad. All 10 things raised by invega were above normal. Minor things like blood sugar or female milk producing hormones. So it stunk mentally and physically.
As a result he finally agreed to change me to Latuda 3 months ago. I've got the worst case of bi-polar now plus voices constantly telling me that I need to rain justice upon the evil doers with biblical vengeance. Today, I stood on a street corner and yelled at cars that narrowly missed people in the cross walk. Drivers on cell phones, drivers not using a turn signal, people accelerating thru a blind turn into the cross walk. I wanted to chase em all down. The voices demanded me to do it. It's also the 1st time I got out of bed in 4 days. Then I came home and cleaned my place for 5 hrs, the voices constantly saying I missed a spot. I must of rubbed every inch of the toilet like 3x. Now I won't be embarrassed if by some miracle I let company come over.
It doesn't seem like either med does a thing and you get all the nasty, debilitating side effects. Ugh. I see my psych again in 3 weeks and might need to change again. Yuck.
Beginning My Journey on Latuda
I am new to this website after doing lots of research on Latuda over the past 3 weeks. For years I had been suffering with anxiety/depression and nothing seemed to work for me. My tendency became to self-medicate with alcohol and that obviously just made things worse. This all started in my early to mid twenties as I slowly became a shell of my normal vibrant and social self. Just a year ago I was diagnosed with Bipolar 2 and the direction of medications prescribed to me took quite a turn. Originally my prescriber had started me on Lamictal to "create a base" for the antidepressant medications to work. At that time I was also started on Brintellix which ended up helping my anxiety a great deal, but left me at an all time low with my depression. After adding Abilify, it seemed things were staying the same if not getting worse with my depression. I was on Lamictal 150mg, Brintellix 20mg, and Abilify 5mg prior to starting the Latuda.
Just 3 weeks ago I was started on Latuda 20mg and told to taper off the Lamictal and Abilify, which I did. As directed, I took the medication with my biggest meal of the day, lunch, and I didn't really feel any effects that first week. After a week on 20mg, I was bumped up to 40mg of Latuda. That first evening on 40mg was probably the scariest I've ever had on a medication. I got home from work and could not settle down. I am usually fairly depressed when I get home from work since I don't know what to do with myself, but this was different. I was restless and somewhat scared but couldn't really identify what was going on. I ordered a pizza at 5:30pm and then felt like crawling into bed and curling up into a ball. I then started freaking out that I would fall asleep before my pizza was delivered so I got even more restless, waiting for the delivery which typically takes 30 minutes or so. At around 6:15 I actually called the pizza place because I was so eager for the pizza to be delivered, and then I called again at 6:30 because 60 minutes was now feeling like an eternity with what my body and mind were going through. The second time I called they apologized as they were having an exceptionally busy delivery night, but they still didn't know when my delivery would arrive. At that point I couldn't take it anymore so I got into bed with my cell phone and started falling asleep. At 7:00pm the pizza delivery guy called and I just told him to cancel the order, which I felt bad doing but there was no way I was going to get out of bed at that point. This was quite an episode for me to go through.
I had read the side-effects of the Latuda and still didn't really think much of what could have caused the episode. The rest of the week on Latuda was fine for me and I actually began feeling a bump in my overall mood and depression on the 40mg. I did not have another episode like the first night until yesterday, although it was a little milder. Thankfully today I had an appointment with my prescriber and I could tell her about those restless episodes, which after reading about the Latuda I thought might be Akathisia, but I wasn't sure. She confirmed that it was most likely Akathisia as a side-effect and prescribed me Cogentin today so I will be starting that along with an increase in the Latuda to 60mg. I am also going to start tapering off the Brintellix as my prescriber wants to see how the Latuda works in monotherapy for me, and SSRI's can sometimes be counter-productive when it comes to Bipolar 2. Additionally I will be taking the Latuda at bedtime since it seems to make me tired. I had been taking it around 1:00pm and I had been wanting to get into bed each night around 7:00 which is way too early for me. The good news is I have slept very well on it, and it has been easier for me to get up in the mornings. I hate to eat another 350 calories before bed but we'll see how it goes.
All this to say, I am really hoping that Latuda continues to have a positive effect on my depressed mood and that the Akathisia can be controlled or goes away. I hate taking another medication for a side-effect but I have never had hope for a medication like I do with Latuda, so I am going to do what it takes to see if this might be the right medication for my disorder. Anyway I just wanted to share my journey thus far. Comments or suggestions are welcome!
Nicotine cravings and boredom on Abilify
I've been taking Abilify for about one month now and it's helping already in a few ways. However, I believe I'm experiencing something that might be described as "boredom" (I've never had issues with that) and intense nicotine cravings. I used to smoke and every once in awhile feel the urge, but this seems related to the medication. Anyone relate? Insights?
Pins and Needles from Abilify?
I started Abilify a few days ago and I'm experiencing the occasional "pins and needles" sensation in my hands. Has this happened to anyone out there? Insomnia is also a major concern but I'm determined to try to stick it out and get used to it (hopefullly).