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Pdoc wants me to switch from Effexor to Cymbalta.  I'm worried about discontinuation effects combined with side effects from starting a new med.  Anyone have any experiences?

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No experience from Effexor to Cymbalta. But I do have experience moving from Lexapro to Cymbalta, and from Cymbalta to Pristiq.

 

I've read the horror stories, but truly never noticed anything in the way of discontinuation effects.

Edited by mjs190

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Have never been on Effexor, but took cymbalta for 4 years, and had to taper very slowly because of the withdrawal symptoms.

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MJS & Cookie, I we'll know and fear the discontinuation effects from Effexor and I imagine with Cymbalta being in the same family it would be similar. I'm hoping that switching one for the other won't be too bad because they are similar. On the other hand, why is he switching me to another med in the same family if Effexor has stopped working? This is horrible timing; I'm starting a new full time job next week.

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I agree that you probably have less to fear, since you're moving from one SNRI to another.

 

In regards to your question as to why your doc chose this route: Effexor has much less of an effect on norepinephrine than Cymbalta, which hits norepinephrine much harder than Effexor. Perhaps more norep. might be useful for your condition?

 

For what its worth, Cymbalta felt so much smoother and less side-effecty to me than Pristiq (a metabolite of Effexor)

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I agree that you probably have less to fear, since you're moving from one SNRI to another.

 

In regards to your question as to why your doc chose this route: Effexor has much less of an effect on norepinephrine than Cymbalta, which hits norepinephrine much harder than Effexor. Perhaps more norep. might be useful for your condition?

 

For what its worth, Cymbalta felt so much smoother and less side-effecty to me than Pristiq (a metabolite of Effexor)

Thanks for the info.  The more info the better.

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It makes sense that if you had success with one SNRI that your doctor would switch you to another SNRI once the first one stopped working. You know that a med from that class works. With other classes your reaction might be less well known.

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