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rowan77

On Epilim (sodium valproate) long do you have to wait to get your blood level checked to see if at therapeutic level

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Don't know if I made title  clear. So I am going up to 1000mg tonight.

 When should I get blood level checked to see if I am within therapeutic range?? A day, a few days, a week??

Also when I reach therapeutic level does it take long for symptoms to settle: hypomania??

Thanks ☺

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Valporate is a very strong anti-manic drug, from your signature as well you're on seroquel (another strong anti-manic drug which I am on also).

It should take about 3-6 weeks for all of that to have an effect. For me it took 2 months to come down from my first psychotic manic/mixed episode. 

I came off my meds before though at another time and I started to get manic and I went back on valporate and seroquel, the seroquel kept me levelled around the same mood (my mood didn't get any higher) for 3-4 weeks and then I balanced out. 

That's the best answer I got, maybe ask your doctor

Edited by The Right Honourable Jimmy

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Thanks Jimmy. Thankfully my mood is still at the hypomanic stage so I'm hoping the valproate will stop it in its tracks before mania hits and causes havoc left right and centre 

However I really like feeling this way. I can do so much while only sleeping a few hours and can get an amazing amount accomplished.

I wish I could stay this way

But I am aware that my mood will escalate further or go into the depths of dark depression

So there you are.

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33 minutes ago, rowan77 said:

Thanks Jimmy. Thankfully my mood is still at the hypomanic stage so I'm hoping the valproate will stop it in its tracks before mania hits and causes havoc left right and centre 

However I really like feeling this way. I can do so much while only sleeping a few hours and can get an amazing amount accomplished.

I wish I could stay this way

But I am aware that my mood will escalate further or go into the depths of dark depression

So there you are.

I've been hypo a couple times this year but the meds keep it there. I try to enjoy it while it lasts while trying not to lose control. My problem is I tend to spend a lot and party too hard. I get the temptetion to not take my meds but I try to fight that temptation.

All I got to say is stick with your meds and enjoy it while it lasts while trying not to lose control. As long as you can be functional and be responsible there is nothing wrong with a bit of hypomania in my opinion. We can't always be perfect. I sense that you are bit stressed about it so all I can say is if you do what your doctor tells you, you shouldn't worry too much about being a bit too happy.

Things like that happen when you're bipolar, it's all about learning to cope with it

Edited by The Right Honourable Jimmy

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My doctor took blood levels after a week.

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Usually depends on how fast they want to titrate you. With one pdoc, it was a month. A different pdoc, it was a week. It appears steady-state should be reached in 3-5 days, so a week should be accurate. They do like to draw a trough level, like lithium.

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I went up to 1200 mg last night. Slept a bit better still restless, irritable and have some racing thoughts.  However I don't think I am quite as bad as yesterday.

Community nurse is calling later to give me clonazapam which my pdoc presctibed as a PRN medication. hopefully that and my other meds will help.

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2 minutes ago, centaurus said:

As others mentioned test after week. Just before morning dose.

Wonder how it works if you are taking the extended release formulation. I only take it at night.

Maybe it is the same as lithium. I took the extended release formulation at night and my bloods were checked 12 hours later

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Just to be different, I took it for migraine, it had zero effect on my mood. I ended up taking 1750mg. They tested me for liver enzymes, not for blood level. And they stopped testing after a year or so. I was surprised to hear that there was a specific therapeutic range for mania.

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2 hours ago, crtclms said:

Just to be different, I took it for migraine, it had zero effect on my mood. I ended up taking 1750mg. They tested me for liver enzymes, not for blood level. And they stopped testing after a year or so. I was surprised to hear that there was a specific therapeutic range for mania.

Yes. My pdoc isn't big into therapeutic levels. It's how the person responds clinically.

However I think he would if I were not to repsond on a what is considered to be a therapeutic dose

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7 hours ago, crtclms said:

I was surprised to hear that there was a specific therapeutic range for mania.

My doctor never said anything about mania. He just said "therapeutic dose".

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So if i take my valproate extended release formulation tonight at 10pm, should I  get my blood drawn at approximately 10am tomorrow to get a blood level, 12 hours after. Or does it have to be that exact?

Is it like lithium in that respect??

Thanks

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Well I took it approx 12 hours before getting valproate level taken. 

Saw pdoc today. Upped my dose from 1200mg to 1400mg.

Here's hoping 

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