Jump to content
CrazyBoards.org

Recommended Posts

I have been on Ritalin LA (20mg) for about 9 months, mainly as an add-on for depression/apathy. Pretty regular in taking it everyday. I've noticed within a month, it wasn't doing nearly as much (as far as increased motivation/energy/better mood), although my focus/concentration is still very good. Also, despite eating a similar diet (taking it on same schedule), it works really inconsistently, like somedays it does nothing at all....

I just took a week-long break from it during vacation, and now that I've restarted, the effect is better again. Is this normal for everyone with stimulants? My doc doesn't want to increase my dose. Maybe I should just start taking my additional IR PRN everyday or take week-long breaks? I worry about tolerance...

Is IR taken twice per day more effective? I worry that if I just switch to IR dosing, i will feel a bit of a "crash" in between, it won't be as smooth...Any thoughts??

Share this post


Link to post
Share on other sites

That's what I figured...is the only way getting around this taking 3-day breaks every week? I've tried skipping weekends, but that doesn't seem to really help. I'm not sure if changing the formulation (to just IR) will make a difference in the effectiveness?

Share this post


Link to post
Share on other sites

Ritalin LA is known for being inconsistent. My pdoc likes Metadate CD and Concerta better.

Share this post


Link to post
Share on other sites

@mikl_pls Thanks for the feedback. Is it true that both Concerta & Metadate have a different release mechanism? Have you tried both of them? I'm wondering if the effect would be more potent (and not just longer-lasting compared to the LA)

For now, I am going back to taking breaks on the weekends, but it doesn't seem to be a long enough break to "refresh" the effectiveness, (if you know what I mean.) It really bums me out, because when I first started Ritalin, it felt like a miracle. I was so engaged, motivated and interested in working on things.

 

Share this post


Link to post
Share on other sites
8 hours ago, Blahblah said:

@mikl_pls Thanks for the feedback. Is it true that both Concerta & Metadate have a different release mechanism? Have you tried both of them? I'm wondering if the effect would be more potent (and not just longer-lasting compared to the LA)

For now, I am going back to taking breaks on the weekends, but it doesn't seem to be a long enough break to "refresh" the effectiveness, (if you know what I mean.) It really bums me out, because when I first started Ritalin, it felt like a miracle. I was so engaged, motivated and interested in working on things.

 

I'm pretty sure Concerta has a different release mechanism than Ritalin LA and Metadate CD (and Aptensio XR for that matter), but I don't know if Metadate CD is different than Ritalin LA in regards to release mechanism. I do know that Metadate CD is 30% IR/70% ER (similar to two IR doses given 2 hours apart) and Ritalin LA is 50% IR/50% DR (similar to 2 IR doses given 3 hours apart) if that means anything. Concerta is supposed to be like 3 IR doses given in some certain interval apart (can't remember) such that it lasts 12 hours.

I haven't tried either of them, unfortunately, so I can't vouch for either of them. The only form of methylphenidate I've ever taken was the IR form. It wasn't effective for me at all, so I didn't bother with any of the extended release forms. I've tried Focalin and Focalin XR, which were equally ineffective for me. I guess I'm an amphetamine guy.

I do know what you mean. My mom had a similar problem when she started Metadate CD earlier last year. She was on 10 mg, then 20 mg, then 30 mg but because she has heart issues our pdoc didn't want her on 30 mg long, so she backed her down to 20 mg again, and it wasn't the same for her anymore. She's on Adderall XR now, 15 mg, and it's not the same either.

But aside from increasing the dose, perhaps switching formulations of methylphenidate, switching to dexmethylphenidate, or switching to an amphetamine might help you? That's just a guess on my part.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now


  • Similar Content

    • By browri
      I'm currently taking Vyvanse, and I've heard that straight amphetamine-based stimulants like Adderall and Vyvanse can be stronger stimulants than the methylphenidate class like Ritalin, Concerta (Ritalin XR), and Focalin. I'm considering talking to my doctor about something more mild, and I'm looking at the methylphenidates as an option.
      What I know about Adderall and Vyvanse is that there are differences. Even if Vyvanse is just the dextro- enantiomer of the amphetamine molecule. What I also know is that dextroamphetamine (along with lisdexamfetamine) has more of an effect on dopamine than levoamphetamine which is found mixed with dextroamphetamine in Adderall, and levoamphetamine has more of an effect on norepinephrine.
      Are there similar differences between methylphenidate and dexmethylphenidate? Where one may effect a certain neurotransmitter more than the other would? I'm curious specifically about pharmacology differences and even the slightest differences in mechanism of action. Curious as to what anyone might have to say here.
    • By Blahblah
      Ritalin has been helping me quite a bit with focus/cognition and "staying power" to complete mental tasks....Unfortunately, sometimes, I feel like I get way too Hyperfocused on 1 thing that is not important and I cannot switch my attention back to the important task/tasks that I need to do!!
      For example: i have a writing assignment due at work tomorrow (I have not started it) Instead, I come here and read way too many posts, then I start deeply researching online some other unrelated & obtuse topic and I just realized that I have wasted HOURS. I have totally procrastinated/avoided an obligation. Oh and also...very wierd, I'll write a long email to a friend, and then obsessively read it over & over & over again to make sure I didn't make a mistake!! Is that OCD or what?
      I also have noticed that my thoughts have been a little more obsessive - like hyperfocused/stuck on one topic/idea and it's difficult to switch gears. Is this bad? I don't want to have to go off the med because I do feel like it has really helped me. Now, I'm a bit worried (I did take more IR today, so perhaps that is why I'm getting this side effect?) Maybe I should just stick with the extended & not the IR dosing.
    • By 0112358
      Used to work great for me - I don't think I've developed a tolerance issue, because I've been taking this drug in the same dose range for years, and not always daily. Anyone else experience this?
    • By cloudmonger
      From what I understand, RitalinSR is intermediate-acting (lasts up to 5 hours) where RitalinLA and Concerta are both longer-acting (like up to 8+ hours) Other than this, is there any other difference between the 2?
      Do you feel different on each of them? For me, with RitalinSR, the effect was fairly quick, peak action within 2 hours, but would wear off usually within 4 hours. The good thing though, was that I would get tired in the afternoon/early evening and sleep really really well. If I were to go on Concerta, would it wreck my sleep schedule?
       
    • By cloudmonger
      Please help. New to this board. Have NOT found effective treatment, spent long periods of time (not on any meds and fairly stable), but still always Depressed.  Main issue severe Depression (along with some misc ADD-type issues) I’ve never experienced Mania. I had a SSRI-induced psychotic episode 20 years ago and for the last 5 yrs experiencing troublesome, erratic “cycling” of intense depression, anxiety, irritation/aggravation, passing suicidal thoughts, my doc thinks this is because my Bipolar is untreated & I need a mood stabilizer.
      Over the last 20 years, I have taken all of the SSRI’s, SNRI’s, Antipsychotics, Lithium, etc with intolerable side effects and horrible withdrawal syndromes...Ritalin is the only thing that helped my Depression & motivation issues (but since moving, no doctor will prescribe it to me.)
      Only med I agreed to try again right now is Lamictal due to it’s low side effect profile. I have some concerns though:
      1.) Does it make you MORE tired (already struggle with low energy and fatigue)?
      2.) Does it effect your Cognitive abilities (i.e. memory issues, ability to think sharply & quickly process info, I have focus/motivation issues!!)?
      3.) Has anyone taken this during pregnancy with no issues?
      4.) Has anyone taken Lamictal & Ritalin simultaneously to treat both the cycling and depression/inattention issues?
      5.) Withdrawal - Been reading increasingly of bad cases of Withdrawal from Lamictal… has me very worried if I try to go off it!!!
       
       
×