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I have been on Ritalin LA (20mg) for about 9 months, mainly as an add-on for depression/apathy. Pretty regular in taking it everyday. I've noticed within a month, it wasn't doing nearly as much (as far as increased motivation/energy/better mood), although my focus/concentration is still very good. Also, despite eating a similar diet (taking it on same schedule), it works really inconsistently, like somedays it does nothing at all....

I just took a week-long break from it during vacation, and now that I've restarted, the effect is better again. Is this normal for everyone with stimulants? My doc doesn't want to increase my dose. Maybe I should just start taking my additional IR PRN everyday or take week-long breaks? I worry about tolerance...

Is IR taken twice per day more effective? I worry that if I just switch to IR dosing, i will feel a bit of a "crash" in between, it won't be as smooth...Any thoughts??

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That's what I figured...is the only way getting around this taking 3-day breaks every week? I've tried skipping weekends, but that doesn't seem to really help. I'm not sure if changing the formulation (to just IR) will make a difference in the effectiveness?

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Ritalin LA is known for being inconsistent. My pdoc likes Metadate CD and Concerta better.

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@mikl_pls Thanks for the feedback. Is it true that both Concerta & Metadate have a different release mechanism? Have you tried both of them? I'm wondering if the effect would be more potent (and not just longer-lasting compared to the LA)

For now, I am going back to taking breaks on the weekends, but it doesn't seem to be a long enough break to "refresh" the effectiveness, (if you know what I mean.) It really bums me out, because when I first started Ritalin, it felt like a miracle. I was so engaged, motivated and interested in working on things.

 

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8 hours ago, Blahblah said:

@mikl_pls Thanks for the feedback. Is it true that both Concerta & Metadate have a different release mechanism? Have you tried both of them? I'm wondering if the effect would be more potent (and not just longer-lasting compared to the LA)

For now, I am going back to taking breaks on the weekends, but it doesn't seem to be a long enough break to "refresh" the effectiveness, (if you know what I mean.) It really bums me out, because when I first started Ritalin, it felt like a miracle. I was so engaged, motivated and interested in working on things.

 

I'm pretty sure Concerta has a different release mechanism than Ritalin LA and Metadate CD (and Aptensio XR for that matter), but I don't know if Metadate CD is different than Ritalin LA in regards to release mechanism. I do know that Metadate CD is 30% IR/70% ER (similar to two IR doses given 2 hours apart) and Ritalin LA is 50% IR/50% DR (similar to 2 IR doses given 3 hours apart) if that means anything. Concerta is supposed to be like 3 IR doses given in some certain interval apart (can't remember) such that it lasts 12 hours.

I haven't tried either of them, unfortunately, so I can't vouch for either of them. The only form of methylphenidate I've ever taken was the IR form. It wasn't effective for me at all, so I didn't bother with any of the extended release forms. I've tried Focalin and Focalin XR, which were equally ineffective for me. I guess I'm an amphetamine guy.

I do know what you mean. My mom had a similar problem when she started Metadate CD earlier last year. She was on 10 mg, then 20 mg, then 30 mg but because she has heart issues our pdoc didn't want her on 30 mg long, so she backed her down to 20 mg again, and it wasn't the same for her anymore. She's on Adderall XR now, 15 mg, and it's not the same either.

But aside from increasing the dose, perhaps switching formulations of methylphenidate, switching to dexmethylphenidate, or switching to an amphetamine might help you? That's just a guess on my part.

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