I wish I had never been placed on it adjunctively for depression/anxiety. I was first embarrassed because it is classified as an antipsychotic. I was on the lowest dose for a few months. I gain about 15 pounds. I haven't been able to return to my pre-abilify weight. So frustrating.
By Distorted Me
Does anyone with BP or BP 2 specifically have any experience with 5-HTP? I've taken it off and on for the last few weeks and have concluded that it has had a definite effect on me. It definitely appears to be activating. I can take 100 mg (Vitamin World brand that also has 125 mg of calcium listed per 100 mg serving of the 5-HTP in 2 caps) and feel just a little bit but if I take twice the dosage within 6 hours I really feel it. I took 150 mg this afternoon at once with 2 caps of Now brand Dopa Mucuna and 2 caps of Vitamin World GABA-Plus (which has Niacin and Inositol as well unlike other brands of GABA) on top of 2 caps of the GABA this morning.
Driving to dinner I felt like I was damn near hypomanic, if not there. If I had not been fully aware of myself and not driving, I might have gone right above what I feel is my hypomanic threshold. I may have actually dabbled with that line a bit for an hour or so. I definitely had to reign myself in a few times after noticing I was getting a little overly excited and happy. It was definitely a nice feeling, I just didn't want to get out of hand being in public with the family like that.
Also of note, I took these capsules mentioned above after being in a pretty crappy but not lethargic mood and I did have a cup of somewhat strong coffee so I should factor that in as well.
I have to think that the 5-HTP is a bigger factor in how I felt today though because I experienced something similar a few weeks ago after doing nearly the same thing, without the coffee, by taking a 100 mg dose in the morning, then another 100 mg dose just after noon that day on a nearly empty stomach. I went kind of haywire for about an hour and got kind of paranoid. Though once I was able to remove the fear by saying fuck-it basically and telling myself to just try to enjoy the ride that day, I felt pretty great. I was noticeably relaxed and calm after that almost tired but i did not want to take a nap because of the GABA I had taken (probably 6 of caps of the same brand over a 6 hour period with little food in my stomach) fearing a benzo-like effect on my breathing. That day, I had no coffee since a weak cup early morning. Since I was felt a little too tired after taking the rest of those caps mentioned, I did have another cup of not really strong coffee and then felt pretty great.
Tomorrow I'll experiment with just the strong coffee I had today and report back in this thread. It was a mix of regular coffee and some espresso I had ground last week - about a 50/50 blend - in a French press that tasted good and strong, but nothing overpowering for my taste.
Edit: Just wanted to include I'm not under the influence of any illegal drugs or alcohol anymore. Today is 24 days completely clean and sober and I'm enjoying the shit of out of sobriety honestly.
Other than that, I've been on the same meds in my signature minus the 150 mg of Bupropion. I've stopped that for 3 days now as it's been too activating for me and has made my temper much worse. Temper has been about 1/2 what it was a week ago now.
I would love to hear from any BP people, especially BP 2 folks, and their experiences with 5-HTP.
By Distorted Me
I know that a lot of bipolar folks take an SSRI as part of their daily regimen of meds and apparently it seems to help. But there's some growing concern in the pdoc world now that SSRI's may be causing manic symptoms and even directly causing manic episodes. I was on SSRI's for 10 years before quitting last October. In chronological order: Celexa, Zoloft, Celexa again, Lexapro, Zoloft again, Prozac, Zoloft again briefly, back to Prozac to close it out.
For me, personally, after stopping them altogether, I was able to see what they were doing to my system. I truly believe they made me much more unstable and greatly increased compulsiveness and just made a bad situation worse. Switching from Lexapro to Zoloft sent me immediately full-on hypomanic for over a month in early 2015. I was high as a kite and on top of the fucking world. It was unreal and so obvious at the time. From the beginning of it, I was certain something unusual was going on. Now I wasn't diagnosed bipolar yet, just depressed, so I didn't even know what hypomania was then. It fizzled out eventually (sigh) but I had at least two more, shorter, and less intense episodes late spring 2015. I've not had anything quite as euphoric as those since.
My last pdoc expressed some concern about the prozac but wasn't very insistent on me stopping it, just that I would want to eventually. I've since read that there is increasing concern in the pdoc community. Yet a lot of bipolar people still take SSRI's and don't seem to have problems.
Do SSRI's seem to help your causes? Do you notice any unusual side effects? Have any of you stopped taking SSRI's and noticed a change? Other comments? This could be interesting.
Can anyone tell me what you take that has treated bipolar depression. I’m too scared to even touch an antidepressant with my history. I can’t get out of depression. When I think of my life since this illness onset I can only think of a handful of healthy times when I wasn’t at least mildly depressed. I am fighting so dam hard, and this is it. I have time off. I’m about to start getting short term disability and I’ll have at least 6 months to tinker with meds. I’ve already been tinkering with them for over a year and nothing is working for depression.
i thought lamictal would do it this time but it’s making me worse.
im desperate. I’m going to seriously look into Latuda with my pdoc but yes I am concerned about anxiety. I do have a goal to get off the .5 klonopin over the next several months. Maybe that is unrealistic or impossible.