I recently had the initial 6 treatments of Ketamine infusions, and that helped my Bipolar II depression (which is treatment-resistant) for about two weeks. Then I had another booster infusion, and that held for a week, then I had another booster infusion, and that lasted a week. These "boosters" shouldn't have to be given more than once every 1-3 months, yet it seems I need one weekly.
So the Ketamine failed to provide prolonged relief.
My only other option now is Electroconvulsive therapy (ECT), which I don't want to do. I know it's gotten better vis-a-vis memory issue side-effects, but I just don't want to do it. I don't like the idea of having my brain electrocuted (however little the electrical charge), and I don't like even the idea of me potentially losing cherished memories.
My question: If I had such a poor experience with the Ketamine, needing weekly boosters, does that bode poorly for ECT therapy? I know ECT also frequently requires "boosters." I don't want to have to go in weekly for an ECT booster. I'm tired.
I've been through the ringer for the past 16 years. I'm just tired of trying to get better. I'm tired and worn down.
Please share your experiences and insights, I'd much appreciate it.
So I was manic for 8 weeks. I am now severely depressed and my pdoc took me of fluoxetine when i was manic, but now she has put me back on fluoxetine 20 mg. I'm worried I will become manic again. I had a very bad manic episode this time and don't want a reccurance.
If you became manic on an antidepressant how long did it take for you to become manic. Was it gradual or sudden? I wonder could I recognize symptoms quickly and go off it.
Hi all I'm new here first diagnosed with ADHD I and now with bipolar 2 and anxiety.
I'm having some trouble with the meds that I'm on. I'm taking between 25 and 50 mg of Vyvanse daily. It helps with my depression, ADHD, and binge eating, but even though I'm a big girl I'm very sensitive to meds in general so my dose is fairly low. Since I was just diagnosed with bipolar in April, the psychiatrist added a mood stabilizer which is Lamictal. It is making me super sleepy but I'm not sleeping well at night. I already know that I don't do well with anticonvulsants because I can't even take 25 mg of Topiramate without being zombie like tired all day. Also my Promethease test shows that I have a gene for processing anticonvulsants less efficiently than other people.
Lamictal seems to be doing the same thing that topiramate does to me, at least to some extent. I am also on 60 mg ER of propranolol at bedtime for a fast pulse and anxiety. I'm averaging about 5 hours of sleep right now and that is not working well for me.
I am really wanting to request doing something different than this Lamictal. I'm definitely feeling more stable, but I cannot function as a zombie with a four-year-old. What would you suggest that I talk with my pdoc about when I go back, if anything? I've made it up to 75 mg of Lamictal and it's killer. My only option I'm thinking is to quit taking it in the morning and try it at night, but that never helped with Topiramate either.
I will say that I struggle more with depression than hypomania but I do have hypomanic episodes--at least a few year with the seasonal changes and sometimes I wonder if I don't rapid cycle as well. I will also add that a concern for me would be weight gain because I'm already in the obese category, though I am losing weight--only with the help of the Vyvanse and dealing with the binge eating and ADHD for the last couple of years since I was diagnosed.
I am currently on two medications, Zoloft 100mg and Lyrica 300mg, and had sort of a weird bought of mood swings over the last two weeks that may have been just work related though I was feeling agitated one day, and flat and depressed the next few days. Now I am sort of about as normal as normal gets, for now.
Different medications have been suggested to me for managing bipolar II and I am sort of hesitant to try something in addition to what I am already on because what if my medication trial goes side ways and it makes me worse? I know start up can be rough but I just don't know if things are bad enough now to start messing around. I was feeling anxious and scared about work (enough that I took a day off to reset myself) and wondered if I could benefit from different meds that are more in-line for treating bipolar disorder.
I feel kind of stuck and wish I was starting from where I am on no meds to transitioning to 1st line treatment for bipolar.
Any thoughts? Anyone start out on meds for MDD and anxiety transition well to meds for bipolar? Med changes are never fun in my experience.
Does anyone else have experience with Rexulti completely destroying their depression? For me, Rexulti almost had a same day anti-depressant effect and controls depressive episodes acutely and astoundingly fast. I literally feel anti-depressant effects in as little as 3 hours after I take it. When I look back to when I was on it, I now realize that I didn't have a single bout of depression during that time, it just was not super effective in controlling mania. I think Rexulti is a hell of an anti-depressant, a way improved drug than abilify with less than half the side effects, no lethargy or cognitive impairment either which is always surprising to find in an antipsychotic. I know it has an indication for adjunctive therapy in adults with MDD but none for bipolar depression... maybe Lundbeck is just waiting for close to the expiration of the patent before the release new clinical trial data and extend their patent after they get the bipolar depression indication approved, but that's just a thought.
Anyone else have a similar experience with Rexulti, brexpiprazole? Please let me know about your time on the medication and if it sat well with you or not so much. Interested in if others are also getting this rapid and significant anti-depressant effect from this drug or if it's just me