Jump to content
CrazyBoards.org

Recommended Posts

Since I've been on Effexor for 7 months, I've had zero emotional depressive symptoms (like the crying, sadness etc) negative ruminations have lessened, no anxiety whatsoever either...

Issue is, I've become more & more lethargic. I sleep a full 10 hours per night and then I cannot get out of bed. I'm not really tired, I just literally cannot get myself to do anything. I am super content just laying in bed for hours. I read crap online for hours, I often take 2 hour naps in afternoon. It pains me to take a shower & go outside. I procrastinate on work/everything... I avoid doing things I need to do just so i can lay in bed! No interest, motivation, pleasure in anything. How can I light a "fire under my ass" again? The same issue happens with other meds that work for depression, but then they cause this!

And no, my doc won't increase my Ritalin (which I have a tolerance to & it stopped working). She won't put me on any other stimulants which seem to be the only thing that help me in this state. Yes, I've tried Abilify add-on...not sure if I want to keep adding more meds or if there something better I can switch out in my situation?

Seems my choice is to either be emotionally depressed or a complete apathetic sloth!!! Any ideas?

 

Share this post


Link to post
Share on other sites
Posted (edited)
1 hour ago, Blahblah said:

 Seems my choice is to either be emotionally depressed or a complete apathetic sloth!!! Any ideas?

Since stimulants are off the table, my suggestion would be to ask your doc about possibly increasing your Effexor dosage....From what I have read, Effexor is more activating at higher doses.

According to drugs.com, the maximum dose for depressed outpatients is 225mg, but I have seen a few people here on even higher doses........Also, according to this dosage guide, severely depressed inpatients can be given up to 375mg:

https://www.drugs.com/dosage/venlafaxine.html#Usual_Adult_Dose_for_Depression

Edited by CrazyRedhead

Share this post


Link to post
Share on other sites

When you tried Abilify, did you take it all the way up to 15 mg? I believe that Abilify has not been given a fair trial unless taken up to higher doses provided akathisia is not a problem. Abilify only began to work for me once I hit 10 mg and 15 mg were better. At less than 10 mg, all I got from it was anxiety.

Share this post


Link to post
Share on other sites

I developed something similar on Zoloft and I actually started feeling more energy when I tapered down the Zoloft. I know you've already tried a lot of meds but maybe Effexor is just not a good fit and something else might work better in combo with abilify etc.? I don't know.

Share this post


Link to post
Share on other sites

I tried Abilify up to 10mg and I got the restless movement/foot/leg shaking thing. I also became an eating machine which is so not me, like waking up at night to go to the kitchen for snacks kind of hungry.

I suppose I could go up on Effexor, but at least with my experience with other antidepressants, at the higher dose, they are stronger and make you feel really numbed out, it's not an "activation" feeling that i ever get, it's a flatness & emotional blunting.

I feel like a stimulant would be the trick, but they are so regulated here. They do not even prescribe Dex or Adderall. Anyway, I get the feeling that with stimulants, you get used to the dose and then you need to either take longer breaks or continue to increase to get the same initial effect.

Share this post


Link to post
Share on other sites
Posted (edited)

@Blahblah, What about Provigil (modafinil),  or Nuvigil (armodafinil)?........They are wakefulness-promoting meds for people with excessive daytime sleepiness.

https://en.wikipedia.org/wiki/Modafinil     https://en.wikipedia.org/wiki/Armodafinil

Nuvigil has a longer half life than Provigil.......They are both controlled substances, but only class IV......Ritalin and Adderall are both class II (more highly regulated)......I don't know how your doc would feel about these, but it might be worth a try to ask.

Edited by CrazyRedhead

Share this post


Link to post
Share on other sites

How about Rexulti? It's like Abilify but supposedly with fewer side effects and specifically the appetite side effect is supposed to be less. I'm not joking when I say that when these meds work, they REALLY work and the difference is like night and day. I can't tell you the bliss I felt when Abilify started to work for me. It was not subtle at all. And yes it was bliss.

Share this post


Link to post
Share on other sites

Sorry you are feeling like this, I feel your pain.  Winter is hell for me, exactly as you are feeling now. 

I am taking Viibryd now after about 6 years on Lexapro.  I am still titrating on the Viibryd and completely off Lexapro, but it feels like the Viibryd has started to kick in.  It seems to be energizing and has lowered my anxiety.  I am getting out and doing something pretty much every day.

I also take Ritalin, it always gives me a boost, sorry it isn't working for you.

Someone in another post mentioned the extended release version of Ritalin might be something to try.

Wish I could help out more.  Do try to do something everyday, even if it is something quick, at least it will give you a sense of accomplishment.

Don't worry about showering.  As the late George Carlin said, "you don't always need a shower, all you need to do is concentrate on the 4 major areas, armpits, asshole, crotch and teeth." :)

I hope you get well soon..

  • Like 1

Share this post


Link to post
Share on other sites
On 5/23/2018 at 6:19 AM, Blahblah said:

Seems my choice is to either be emotionally depressed or a complete apathetic sloth!!! Any ideas?

 

 

Anhedonia — lack of pleasure or inability to enjoy everyday things — is pretty common with major depression, even when being actively treated and some symptoms resign. I know it's definitely something I struggle with a lot of the time. I also took Effexor XR at one point for a couple of years, going as high as 300mg, but never saw much improvement beyond when I first started taking it, regardless of dosage. I can manage, but I wouldn't say I feel great (or even good some days).

Eventually though, largely due to a return of depressive symptoms triggered by life stuff, my PDOC and I decided to switch off of Effexor and try something else. He gave me a lot of freedom to research and make my own decisions, so initially, I tried modafinil (Provigil) because I figured it'd be easier to add than take away; plus, it's not a stimulant, which I personally would rather avoid, if at all humanly possible. But, ultimately, it didn't do much, if anything, even at the max dosage (400mg/day), so I came off of it.

Ended up on duloxetine (Cymbalta) because it was another SNRI and I wasn't sure if I wanted to quit SNRI's all together yet (worried what it would do if I came off the NRI portion of the drug and went with something else, like an SSRI, that doesn't affect norepinephrine receptors). As it stands right now, I'm on 80mg and I feel mostly okay. My PDOC said the ceiling for the drug is 120mg/day. I've thought about increasing it, mostly to see if I'd get any benefit at a higher dose, but I'm also afraid it won't do anything and I might have to find another drug again.

Long story short: you still have quite a bit of Effexor to play with (the highest dose I've seen is 425mg/day), if you're so inclined; you could try modafinil like I did (assuming your doctor is open to it and you can afford it if it's not covered by insurance) or a different SNRI entirely. There are newer, novel anti-depressants that might do some good, but I don't know much about them and probably wouldn't try them anyway 'cause they're still patented and expensive af. Beyond that, there are tricyclics that sometimes affect both serotonin and norepinephrine, but they're also notoriously bad in regards to side effect profile; plus, I don't know your history, but your doc might be reluctant to try them because they're very cardio-toxic when used in an OD attempt.

Share this post


Link to post
Share on other sites
On 5/23/2018 at 5:19 AM, Blahblah said:

Since I've been on Effexor for 7 months, I've had zero emotional depressive symptoms (like the crying, sadness etc) negative ruminations have lessened, no anxiety whatsoever either...

Issue is, I've become more & more lethargic. I sleep a full 10 hours per night and then I cannot get out of bed. I'm not really tired, I just literally cannot get myself to do anything. I am super content just laying in bed for hours. I read crap online for hours, I often take 2 hour naps in afternoon. It pains me to take a shower & go outside. I procrastinate on work/everything... I avoid doing things I need to do just so i can lay in bed! No interest, motivation, pleasure in anything. How can I light a "fire under my ass" again? The same issue happens with other meds that work for depression, but then they cause this!

And no, my doc won't increase my Ritalin (which I have a tolerance to & it stopped working). She won't put me on any other stimulants which seem to be the only thing that help me in this state. Yes, I've tried Abilify add-on...not sure if I want to keep adding more meds or if there something better I can switch out in my situation?

Seems my choice is to either be emotionally depressed or a complete apathetic sloth!!! Any ideas?

 

Have you tried taking a break from the Ritalin? It can work wonders. Just a week off and it may work as well as it used to. It did for me. Worth a shot. 

Share this post


Link to post
Share on other sites

Yeah, I've taken short breaks on & off of it...It seems it always eventually sort of "poops out" quite quickly again. I've been completely off it for over a month now, so perhaps I can try it again.

What dose are you on and what schedule do you use? (like: On 2 months, off 1 month and so forth?) If I just take breaks on weekends, it doesn't seem to be a long enough break.

  • Like 1

Share this post


Link to post
Share on other sites
Posted (edited)

I’m on Adderall, and I typically take weekends off and during the week when there is nothing needing done where it’s necessary . I can’t remember now, have you taken Adderall in the past?

Edited by DammitJanet
  • Like 1

Share this post


Link to post
Share on other sites

@Blahblah I'm so glad to see your post! I've been feeling the same lately. Thought we had my Rx mix at a good stable place finally (and for several months now), but about 4 weeks ago, things started to come apart at the edges. The house is a disaster. I sleep 'til noon and stay up 'til 3 AM. One day last week, I was so out of it I missed my weekly checkin with academic advisor _and_ my therapy appointment. Time to make an appointment with the pdoc...

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now


  • Similar Content

    • By Stephielove77
      Hello, amigos. It’s day 3 on Ritalin SR 20 once a day,  finally prescribed after « doctor shopping » and faulty antidepressant tryouts. It kicked in right away however I did  take a nap today shortly after taking it but that’s probably my body’s usual reaction to fighting off anything new to the system. It worked right away which is a miracle!!!!!!  I have the worst job in the world which is dishwashing in my family’s restaurant, basically waiting to die. Well! Let me tell you, the soul crushing agony of a wasted 41 year old woman’s life were momentarily alleviated by focus, order, and execution. I just got on with it. S’ppose it coulda been a Placebo  (great band) effect but I’ll take it.                                Having run the gamut of, oh, every antidepressant to no avail, the last being Trintellix, which after a month left me exhausted, though I’M SURE it would’ve worked after six weeks 🤪                                          So experienced créatives,my questions to you are:  Has adding an antidepressant to your current stimulant (preferably Ritalin) made you exhausted/fried and if so for how long? Is Prozac a lost cause, especially according to Dr Charles Parker ? Ixnay on Celexa, Citalopram, Abilify, Viibryd, Trintellix, Cymbalta, Effexor...those last three were great for a 2 or so months then I slept all day, modalert didnt make a dent..Zoloft I would say I’ve had the most success with but maybe I should do the Ritalin for a couple months before reintroducing? And finally, Wellbutrin was great until the Cicadas in my head....I.E Tinnitus made me want to inpatient myself. Thank you!!               tl;dr dx’ed  MDD, no bipolar traits and other failed depression treatments include Valdoxan (Agomelatine), Doxepin, Celexa was a goddamn disaster. I aint doin’ no MAOI’s, thanks. Also I live in France and Ritalin was extremely difficult to get prescribed.                                         Thanks, Steph 
    • By Gatorgirl
      I don’t know where to go from here. My issues seem so endless and treatment-resistant even though I’ve never been told that. I just feel so lost and scared that nothing and no one can help me...
      my issues consist of severe clinical depression, panic attacks, generalized anxiety, OCD, and depersonalization/derealization.
      I’m on meds... Anafranil 200 mg, Klonopin 2 mg, and Rexulti 2 mg. I still just feel so blah, hopeless, dead already, etc. 
      Can anyone give me suggestions of where to go from here? What meds to try? I had genetic testing done too for med compatibility of that helps at all...
      Thank you kindly for your replies 😊 
    • By solidandvoid
      i've been having this thing where my eating disorder and adhd kind of combine forces: i'll take 10mg ritalin LA (+150mg bupropion) in the morning, not feel hungry all day, then when it wears off and i get hungry again i overeat, feel guilty, and struggle not to vom. tbh even if it's a normal amount of food i'll feel bloated and want to vom.
      sometimes i'll try to get myself to eat while the medication's still in effect by smoking weed, but i end up b/ping almost 100% of the time. i'm seeing my psychiatrist soon so i'll discuss this with them, but i'm curious if anyone else has had these experiences.
    • By Blahblah
      I just re-instated Ritalin (after about a 3-month break) My pdoc said I could "play" with the dosage a bit, because I was previously on a low dose (20mg extended morning, sometimes added 10mgIR afternoons). Problem is, coverage is very inconsistent. I've started loads of focus-intensive work/required research/reading projects, and I really depend on it more to function in this role.
      I'm getting really varied effects from it...not sure what to do. It helps me focus on detailed tasks - and I start out feeling no appetite/nauseous (which is normal effect, I always eat decent breakfast like oats/yogurt/water, about 40 minutes after taking it), but then I'm starving like 3 hours later, and really physically tired fairly quickly (on extended dose)...I took a 10mgIR dose (after eating lunch, feeling physically tired) and I can still mentally focus fine, but still feel very tired,  like I need to lay down and I'm still abnormally hungry!! Is it simply not working as it should, or am I metabolising too fast?
      I'm not sure how to adjust my dosage or what works best for you guys? Really bummed out, I need this to work. I don't want to be popping it like candy all day!
    • By Blahblah
      Quick backstory, I was on Effexor (75mg-150mg) for only 7-8 months, my pdoc tapered me off very slowly (using Prozac as a bridge) over a period of about 5 weeks. I've been completely off both meds now for 2 months. I did not have major withdrawal symptoms (except light fatigue/dizziness) and yet I am STILL getting these intermittent (mild) brain zaps sensations and brain fog - usually in the afternoons/evening.
      I am very worried that they will never go away... I have been taking many supplements (including Fish Oils, NAC, etc) for many months, exercising, eating healthy. How can i make them disappear for good?!
×