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I have been a long time user of depakote, over 15 years and while it has done a fantastic job of helping to stabilize my moods, with the addition of geodon, I am unhappy with the major hair loss it has caused.  My pdoc has recommended either lithium or vraylar as a substitute.  Has anyone switched to either of these two meds from depakote?  What are your experiences?  Side effects?  I am anxious to stop the hair loss but am afraid to give up the stability I have.  Another concern is weight gain.  I have recently lost 75 pounds of seroquel weight and am in no hurry to gain it back.

I have bipolar disorder with psychotic episodes that is currently well controlled.  Any suggestions?

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Currently just 40 mg of geodon and 1500 mg of depakote.  Plus synthroid, nifedipine, Allegra.

teri

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Personally I had lithium take over for my Depakote and liked it better but be warned it can occasionally cause hair loss too. Have you ever tried vitamins? I think they gave me zinc and folic acid when I started Depakote 

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I have tried vitamins.  My pdoc recommended zinc and selenium.  I have been taking a hair vitamin for the last year, added a new one recently and switched to a natural hair growth shampoo.  Still losing at a great rate.  It’s so bad I’m thinking of buying a wig.  Saw that you were on vraylar, what did you think of it?  What made you stop it?

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Some people find it activating...I found it neutral in both sedation/activation and weight gain/loss. I liked it, seemed to Cover both ups and downs. However, I always took lithium with it. Pdoc and I agreed to taper off because once I got stable because clozaril seemed to be all the antipsychotic I needed. Be aware- it can be very expensive. However, if you're keeping the geodon it might make more sense to have a mood stabilizer (lithium) on board. That's much more common than just two antipsychotics 

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