I made the prolonged mistake of not refilling my meds for about 3 weeks. Whoops! I'm on 20 mg of aripiprazole (Abilify) and 200 mg of lamotrigine (Lamictal), which I've been on for about 2 years in varying doses. So my friends finally took me to the pharmacist today to pick them up, but I want to make sure I'm safe about going back on. Should I slowly increase dosages? Or can I just start back on my normal amount ASAP? I would go to a psychiatrist to figure this out, but I there aren't any appointments for another 2 weeks.
Hello out there,
i am so very desperate. I was perscribed Abilify 2.5mg in July 2018. Because I was struggling with inner restlessness and my symptoms were returning, I decided to discontinue at the beginning or December 2018 (5 weeks ago). Since discontinuing I have experienced anxiety that is terrifying. I have very little rest from it... terrible insomnia. Many days I feel I can’t go on. I returned to my doctor a week ago and she has started me on Sertraline, and has given me a few diazipam. I was so desperate I went to the hospital yesterday and have been put under the care of the psychiatric team and have been given some sleeping tablets to help me sleep, which didn’t work very well last night. I am scared that the withdrawals will never end. Is there anyone out there that has experienced similar?
By l'appel du vide
Hello everyone, I hope everyone's December has been off to a good start. I am back, on the med merry-go-round and also sober from opiates.... Again (16 days as of now).
So I was taking wellbutrin as an add on to my Prozac, and it really didn't help and might have made me worse, losing dramatic amounts of weight, a lot of intrusive thoughts, very depressed (though that's probably just it not doing much for it. And getting off drugs.) so I'm now on the Rexulti starter pack.
I'm here seeking others experiences with abilify and rexulti, since they are both dopamine partial agonists and 5-ht1a partial agonists, amongst other things. I'm very nervous about taking an antipsychotic for depression, though... And just want to know of other's experiences starting these medications. How were the side effects? If you had any, did they eventually go away? Did you gain weight?
I appreciate anyone who shares their experience. I've asked about these meds before, but I'm so nervous about it I just want reassurance. A lot is changing around me. Thank you all so much, and I hope the holidays have been treating you well.
Hello, it has been awhile!
Well, my old psychiatrist retired and I am now stuck with a new one. A tele-med provider. Without really letting me know if they read my chart (they even made mistakes when asking what meds I was on now) they prescribed me topamax to take alongside my usual anxiety med due to (duh) increase in anxiety. They said the added benefit would be that I would be able to lose weight as well, since my previous meds made me...ahem, chunky. And I told them I have body issues.
Here's the thing. I did a little research about the weight loss and all studies said that it was beneficial to those who were bulimic or over eaters. I have history, and deal with restrictive eating. Making my appetite less would be a very stupid move in my opinion. My other concern is that there is a side effect where your eyes can suffer permanent damage. Not likely of course, but it is noted. I have a degenerative eye problem and I feel that it would be risky to take something that could make my eyesight worse. Of course there is the caveat that if I notice anything like that I can stop the med, but would my eyes regain the vision they "lost"?
I talked to a pharmacist today and they told me it would be very unlikely that I would have any visions problems other than blurriness and that most symptoms are dizziness, hard time focusing, etc the usual. They kind of glossed over the eating part too, saying to just talk to my provider. I have an appointment in a month, and with the Holidays coming up, I decided not to start taking the topamax so as not to ruin any festivities I hope to have with my family.
I guess I just needed to vent a bit because it doesn't seem like my new provider is listening to what I have to tell them...since they keep asking me things that are in my chart already! I miss my old psychiatrist a lot, and don't like this new tele-med set up. In any case, I would love to hear from others who have taken topamax for anxiety and how it worked for them. I know everyone is different, but I'd like to get some feedback nonetheless.
Abilify (Aripriprazole) is a partial agonist on dopamine receptors with 60% the activity of dopamine on receiving neurons and 75% activity of dopamine on firing neurons . Abilify is the only antipsychotic which can increase dopaminergic activity in the mesocortical pathway through dopamine partial agonism. Abilify is a 5HT1A partial agonist (68%), which causes dopamine levels to go up in the prefrontal cortex. Abilify is also a 5HT2A antagonist; which has antipsychotic and antimanic properties .
Here are the Four Dopaminergic Pathways and Abilify's Effect on them
1. Mesolimbic (Abilify decreases activity)
2. Mesocortical (Abilify increases activity)
3. Nigrostriatal (Abilify dampens down)
4. Tuberoinfundibular (Abilify does not cause prolactin release unlike dopamine antagonist antipsychotics. In fact, even low doses of Abilify can reduce prolactin release caused by dopamine blockers).
Abilify reduces neurotransmission in three of the four dopaminergic neuronal pathways.