I couldn't decide what section this post would be most appropriate in. If this isn't it, sorry.
I'm new here. My name is BP 2, MDD, PTSD and WTF.
Any geeks want to take a crack at deciphering what two doctors so far can't really speak too intelligently to me about?
Here's the jist from the test:
SLC6A4 - S/S (2 red, higher risk of non-response)
5HT2C - C/C (2 red, weight gain risk)
MTHFR < C677T - C/T (red T), A1298C A/C (red C) > Intermediate activity
CACNA1C - G/A (red A, Intermediate risk of altered neuronal signaling)
CYP1A2 EM - 1A/1F (red 1F)
I had the genetic testing done through GENOMIND and have absolutely NO confidence that either Doctor I have seen really knows what it all means. I know some, from research. I am very wrapped up in this right now, obsessed. Need answers. Need puzzle solved. Need clarity.
Here's what I know: I cannot take SSRIs. Can't take APs. Been taking EnLyte for 4 weeks, currently on low dose Trileptal and THAT'S IT. OFF all other meds, flying almost without a net for first time in many years, nervous about that. Started 5mg Trintellix yesterday, hoping with the methylation I'll experience benefit s of a drug for a change. Was on Lamictal for ten years, which was only ever barely helping, but enough to keep me functioning, sort of. That's out now. No SSRIs ever helped and in some cases made me crazy. Same with Anti-psychotics. Now, from the test, I know why (kind of).
The gene test says with L-Meth supplements that SNRIs can work where they wouldn't before. Only one I can take of those is Pristiq, though, and for some reason I'm afraid of that. It doesn't mention whether drugs in the "Other" class might do the same - Viibryd or Trintellix, for example. Any thoughts on that? Neither drug was effective in the past, but I did tolerate them fine. Might they now be able to work with the L-Methylfolate in the mix, even though they aren't SSRIs or SNRIs?
Cymbalta and Remeron are out of the question because of the CYP1A2 deal. Effexor and Wellbutrin are out because of the CYP450 deal. So my options are limited. I'm avoiding MS for now. I want to see if I can get a damn AD to actually do something first. I know, maybe backwards. But that's where I'm at.
At this point, any damn comments, feedback or whatever is welcome. But if anyone knows who/where I can get a real assessment of the gene results PLEASE let me know.
Thank you and good night.
By Alien Navel Cord
So last Friday I went to the neuro psychology center, and they started me out for part 1 of testing to see if I have ADD. The first part of it, I was put into a little room with a laptop, and had to select 'true' or 'false' for 378 questions, with statements like, "I am a loner and have no friends" and "I enjoy being alone" and other things that I answered 'true' to that will make me sound like a socially avoidant sociopath I am sure. I don't know what the point of that one was really. A preliminary "what is your flavor of crazy" test?
Then I was walked across the parking lot into their other building and took a special kind of test (I forgot what it is called) where I had to do various things like hit enter as fast as I could as soon as I saw an image flash on the screen, and I had to read a few stories and come back to them later and answer questions about the stories to the best of my ability. I had to identify patterns lit up in boxes and then re-create those patterns using the 10-key pad. I think I rocked at that one...
It took about 2 hours to do and I'm scheduled for wednesday something called EEG and have some specialists talk to me and do more tests on me. All this to see if I have Attention Deficit Disorder.
During my initial consult with the neuropsych, he mentioned that it could be ADD where your brain slows down and doesn't process information that is being tossed at it... or that since I am bipolar, and likely have been since a younger age than most people think, that my brain is sped up and it can't catch up or slow down enough to process information that is being tossed at it. He thinks its one or the other and we're about to find out! Either way I just want the concentration issues to stop. I need to be able to focus on things, so very badly. In the meantime I have found that large amounts of caffeine (energy drinks) tend to help with my concentration for brief periods of time...