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rowan77

Prozac or any SSRI cause activation and agitation in Bipolar

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In your experience  have you taken an antidepressant specifically an SSRI and it made you activated, agitated, irritable and unable to sleep

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Zoloft and Lexapro made me manic...but that was before I was diagnosed with bipolar and on a mood stabilizer. I was able to take Effexor and Cymbalta for a long time without getting manic. I'm on Prozac right now and so far no issues.

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Lexapro without a mood stabilizer made me irritable, agitated, and I think caused akathisia (it's far enough back that I can't remember what it felt like and I didn't know what it was back then).  It didn't cause sleep issues. 

I've been able to take wellbutrin without one while also taking lithium, but the wellbutrin was stopped when I landed in the hospital for mania.  I don't know if there was a direct link between the two, though, because I had been on it for a good 3-4 months before that happened.

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11 minutes ago, looking for answers said:

welbutrin without a stabilizer

Has wellbutrin @ 300mg XL with a stabilizer been treating you well?

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1 hour ago, argh said:

Has wellbutrin @ 300mg XL with a stabilizer been treating you well?

 

1 hour ago, argh said:

Has wellbutrin @ 300mg XL with a stabilizer been treating you well?

it has amazingly

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Any time I take any SSRI I feel like once it’s in my system I’ve smoked crystal meth. 

Edited by Chrisalt87
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I was put back on prozac 20mg for 2 weeks and then on 40mg for 3 weeks and my  mood has definitely improved and thankfully no adverse effects so far !

 

Edited by rowan77
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My reaction to lexapro was pretty similar to dancesintherain - irritable, anxious, agitated and what I thought was akathisia, although my psychiatrist at the time told me it couldn't cause that. She also denied that I could possibly be bipolar despite very clear (in retrospect) hypomania, so there's that. Celexa was actually less problematic for that, although without a mood stabilizer I eventually became hypo and then cycled down to depression and it didn't work anymore for that. Similarly, Zoloft helped with my depression initially without immediately causing hypomania, although like celexa I eventually returned to cycling. I still take it with lamotrigine now, and even though it felt like it had stopped working prior to adding lamotrigine, if I try to lower it beyond 100mg, my anxiety starts to get worse.

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On 8/10/2018 at 3:28 PM, rowan77 said:

In your experience  have you taken an antidepressant specifically an SSRI and it made you activated, agitated, irritable and unable to sleep

Zoloft was the only med that did this to me. I have tried every other SSRI and no problems (apart from a bit of temporary activation/ start-up effects)

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I had no issues on prozac.

Paxil and lexapro seemed to worsen my depression over time, but after tapering off I went into what I'm pretty certain was hypomania.

I'm not diagnosed with bipolar, thus never took a stabilizer. but I strongly suspect I have bipolar II. 

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