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notloki

Metformin Promotes Neurogenesis and Spatial Memory Formation

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The Scientific Method requires replication of test results, one study alone does not mean anything until it is replicated by others using the same methods and the same results are received. Metformin (Glucophage), an old diabetes drug that most Diabetes II patients are familiar with, also seems to increase or improve adult neurogenesis and spatial memory formation. This means neurological cell growth and a special kind of memory. Depression affects both of these, or they may play a part in causing depression. 

Here are 2  studies confirming the same hypothesis: 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468946/

https://www.ncbi.nlm.nih.gov/pubmed/22770240

Edited by notloki
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Having not actually read either article yet, my off the cuff wondering is whether it's a similar mechanism that allows intranasal insulin to convey some protection from Alzheimer's.

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      The Scientific Method requires replication of test results, one study alone does not mean anything until it is replicated by others using the same methods and the same results are received. Metformin (Glucophage), an old diabetes drug that most Diabetes II patients are familiar with, also seems to increase or improve adult neurogenesis and spatial memory formation. This means neurological cell growth and a special kind of memory. Depression affects both or these, or they may play a part in causing depression. 
      Here are 2  studies confirming the same hypothesis: 
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468946/
      https://www.ncbi.nlm.nih.gov/pubmed/22770240
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