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clinic

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  1. All SSRI/SNRIs except paroxetine gives me crying spells for no reason. Does anybody have any suggestions for treating panic symptoms apart from benzos? I take clozapine 200, paroxetine cr 37.5, clobazam 10mg
  2. Yes, after taking it at bedtime, i felt sedated till afternoon on it. Plus it has alot of drug interactions. It specially doubles the clozapine or any other antipsychotic blood levels
  3. Although literature suggests food does not effect paroxetine(paxil) absorption. Does anyone have any studies or link which suggests otherwise ?
  4. Also as i taper paroxetine up to 37.5mg, right now on 2nd week on 25mg im feeling slight like crying and dry mouth in afternoon. I hope it goes away in 3rd week
  5. Yea i have tried 50mg for 1-2 days. It makes me feel like crying and gives me palpitations. Should i give it more days ? Maybe i can split 12.5mg in half and try total 43.75mg instead. I've not tried 43.75mg though I'm looking for add on. I'm not going to stop paxil ever cuz my mood is too good on it. I just dont know why i tolerate paxil and not other SSRIs. I dont want ADs which increase dopamine cuz that might worsen psychosis just like sertraline does for me
  6. @mikl_pls I stopped paroxetine about a week ago. I started it again and now I'm on my 2nd week(taking 25mg) and I can't explain how much better i feel, my mood is very happy plus i feel like my cognition(problem solving skills and somewhat memory) has improved as well. I used to take 12.5 in morning and 25mg in evening. My mood and cognition is only better after evening 25mg dose. In morning i dont feel much mood/cognition improvements after taking 12.5mg dose. If i increase my morning dose i feel sleepy. So far i can tolerate total 37.5mg. I've tried 50mg but i get restless and crying feeling on it. Maybe I can try half of 12.5mg, that would be 37.5 + 6.25 = total 43.75mg dose So my question is should i try increasing morning dose from 12.5 to 25mg and see if sedation improves ? Will I stilll feel cognition improvements if I'm feel sleepy ? I've read your memory goes down if your feeling sleepy. Paroxetine works for mood or maybe ocd. But it is not helping panic disorder(only my benzo clobazam works). But i get cognitive and memory decline on benzo. Thats my 2.5 year experience on it. I will also decrease my benzo to improve cognition. I dont know why i tolerate paroxetine and not other SSRIs. I get crying spells on the very 1st day on them I'm brainstorming this study[1], to see which antidepressant i should try for anxiety. Check out page 1363 or page 7 on your pdf. [1] https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32802-7/fulltext [1 pdf] https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932802-7
  7. But I got this weird feeling only after starting paxil again.
  8. I used to take 37.5mg CR paxil(paroxetine) for 2.5 years. I made a big mistake stopping paxil(paroxetine) cold turkey for 3 days. And now after starting it again im having weird feeling on it like im feeling Flu-like symptoms(very cold), shivering. or maybe its seizure/jerks. But I got this weird feeling only after starting paxil it again. During those 3 days when the med was stopped i was okay. Is it withdrawal symptoms or something else Its been 3 days on it after stopping, I will give it few more days to see if this weird feeling goes away. I cant explain right now what im feeling. RIght now im on 12.5mg, will slowly increase to 37.5mg I took paliperidone 3mg and I had severe EPS side effect on it(pseudoparkinson). I couldnt talk, move. My whole body was slow in movement, slow walking, slow speaking, my entire body seemed slow in every aspects. So it turned out paroxetine(paxil) was increasing the blood levels of paliperidone. So we stopped it. My situation was very bad, so my dad who is ignorant about meds told me to stop paroxetine as well. Following my dads advice was a mistake.
  9. I tried olanzapine 2.5mg for 2 days but it was making my cognition worse so i stopped it. I was not able to say sentences properly, thoughts stop in the middle of a sentence, confused about what i wanna say I think i stop meds too soon. Maybe that cognition side effect will go away ? We can start with olanzapine 2.5mg for 1 week then 5mg from 2nd week. Then we reduce clozapine from 175 to 100mg
  10. Yea beta blockers also give me crying spells. When i was on clozapine 100mg, I could tolerate any SSRI. When i had relapse we increased clozapine to 200mg, thats when i stopped tolerating any SSRI. All gave me crying spells. There is a study which says clozapine worsens anxiety symptoms here --> https://pdfs.semanticscholar.org/2c84/f4256c6602634dbab1e23942307f0ac0883d.pdf Right now if I take high dose benzo like clobazam 20mg and take SSRI. I can tolerate them but if benzo is reduced, I cant tolerate any SSRI at all. I have just updated my about me page, all the meds i have tried https://www.crazyboards.org/profile/40990-clinic/?tab=field_core_pfield_13
  11. I quit some benzos too soon. I might try clonazepam again soon for few days and see if crying spells goes away. Bed wetting starts at 275mg clozapine, not on 200mg clozapine.
  12. Antidepressants Fluoxetine 20mg → crying spells unless taken with high dose benzo clobazam 20mg Escitalopram 5mg → crying spells unless taken with high dose benzo clobazam 20mg Desvenlafaxine 100mg → crying spells unless taken with high dose benzo clobazam 20mg Vilazodone → crying spells unless taken with high dose benzo clobazam 20mg Sertraline 50mg → worsening paranoia Clomipramine 25 → worsening psychosis
  13. My current benzo(clobazam) works great but is causing alot of sedation on target dose(10mg). I take 5mg now. There was no sedation before. I’ve been taking it for 2.5 years. Its like have developed opposite of tolerance. Here’s list of benzos i have tried Alprazolam 0.25 → worsening anxiety and psychosis Alprazolam 0.5 SR + clobazam 15mg → Bed wetting Clobazam 10mg → Works great for anxiety/jerks but sedation problems from 5mg and memory problems from 10mg and above Clonazepam 0.25mg + clobazam 10mg → crying spells Diazepam 2.5mg + clobazam 10mg → bed wetting Lorazepam 0.5mg + clobazam 10mg - worsening anxiety/psychosis, crying spells, feeling sleepy in afternoon
  14. I want to take SSRI but i get crying spells on them except Paroxetine. Only paroxetine is tolerable but it is not working for anxiety. I want to take another SSRI but I'm fed up trying them as I start feeling like crying or sometimes I actually cry. My pdoc theory is that I quit SSRI too soon for it to work. He told me to take low dose benzo along with SSRI. But i have to take really high benzo like clobazam 20mg for me to tolerate SSRI. But if i reduce my benzo i start crying again. And high dose benzo causes severe sedation and cognitive decline I dont know what to do.
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