Bipolar 2 with no meds and just therapy? in Bipolar Spectrum Disorder - The Pole Dance Posted Friday at 07:17 AM As I understand it, bipolar can never be managed without meds. And if you ask around, you will hear all kinds of horror stories of what happened when BP people stopped taking their meds, me included. That’s not to say that you can’t have remissions without meds, something that used to happen to me in my younger days, but not any longer. It’s just that if you have BP, you will have episodes if you’re not medicated, and probably nastier ones at that. That said, it’s possible to go years on end while trying various med regimens, all without having much—if any—success. Typically, depression is the hardest thing to treat, followed by mixed episodes, then mania, then hypomania. I have BP I with psychosis and mixed episodes, and the psychosis, while it can be really, really awful, is actually the easiest thing to treat, because I respond extremely well to one particular antipsychotic, which also works very well on my manic and mixed states. But the depression? Damn. I can sometimes go for years on end in a severe form of that state (my pdoc calls it severe, although I call it moderate, in order to distinguish it from the crashes). And then, when the depression does finally end, I invariably become manic or mixed. And then I almost always go right back to being depressed again once that’s over (but not this time, thankfully). It’s worth noting that you don’t always have to be on a ton of meds. While I have been on as many as 10 psych meds simultaneously in the past, I am currently on only 1 (Depakote), and I have been in full remission since May. My pdoc said that most of his patients who have long remissions are only on one or two meds, in fact.