I had 5 sessions/week for about 3 months starting in Nov. 2019 & felt remarkably better within 2 weeks. After finishing the round, I felt better for about 10 months, then was back where I started. I'm maxed out on Effexor & Wellbutrin. Also on Seroquel and hormone replacement therapy (I'll risk cancer instead of mood swings and sleep disruption.) I've been on Spravato (cousin of ketamine) weekly for about 3 months - 2 snorts per nostril - and it helps. A lot. Both of these are so much easier than the ECT I had in 2015 & 2016.