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    science, my children, South Park

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  1. How are you doing, crtclms?

    How is your husband doing? 

  2. A great site to learn correct, up-to-date, information about MAOIs is PsychoTropical Research at https://psychotropical.info/ . At the site, you can also get the modern "MAOI diet" (up-to-date with current practices in commercial food preparation -- versus the ancient lists you see elsewhere that were created 75 years ago). The site is the creation of Dr. Ken Gillman, who is an expert in SSRI syndrome, with many journal articles published in quality peer-reviewed medical journals. I'm currently on Emsam. I'm a fan of MAOIs. Emsam has a much better side effect profile than any SSRI I was on -- as the side effects I have on Emsam are essentially none (did have some insomnia at first, but even that has resolved). Emsam is outrageously expensive now. When I first started taking it, it was $400 for 30 patches. Now is $2000. Outrageous. Tranylcypromine and phenelzine should be much cheaper.
  3. VE, I assume you have repetitive strain injury (RSI) on your left hand? That sucks hard. I think it’ll be a while before you can use a keyboard for long periods. I would suggest you recruit someone with IT skills to implement the new chat system for you. Perhaps headrift could implement a chat system you like? Otherwise, lots of depressed IT people out there who might volunteer. Also, do you still need money? How much? I should soon have enough income that I could contribute some serious cash.
  4. Fascinating. Rantidine is an H2 blocker. Seasonal allergies are usually treated with H1 blockers. It appears that rantidine has some H1 activity, or H1 and H2 blockers together are better than either alone (see, for example, http://www.respiratoryreviews.com/jan01/rr_jan01_H1andH2blockade.html ).
  5. An internet search of aspartame (and other artificial sweeteners) and depression will turn up some links to credible sites that suggest that people prone to mental illness should avoid them. You'll also find a million sites that say that aspartame is the Devil's toejam, etc. Anyhow, I gave up diet sodas in March - I figured it was free to try it. I would say my mood improved. I still drink some regular soda - but limit myself to 1 per day, due to the calories. In the past couple of days, I tried a couple of diet sodas - and yuck, did they taste bad. Must be and acquired taste. I would also note that I drink less total fluid after giving up diet sodas. Which is a positive, if you're prone to heartburn.
  6. "In an article for Forbes magazine, Dr. Michael Economides, a professor of engineering at the University of Houston, commented on the Gasland scene of "a man lighting his faucet water on fire and making the ridiculous claim that natural gas drilling is responsible for the incident. The clip, though attention-getting, is wildly inaccurate and irresponsible. To begin with, the vertical depth separation between drinking water aquifers and reservoir targets for gas production is several thousand feet of impermeable rock. Any interchange between the two, if it were possible, would have happened already in geologic time, measured in tens of millions of years, not in recent history." https://en.wikipedia.org/wiki/Gasland
  7. Heh, it seems like the main criticism is taking an individual story and generalizing it to the entire population. Uh, that narrative method is like breathing for TV, radio, and newspapers. Make the story personal - focus on one person, or one family's story. Done all the time. Why? Well, a story about statistics is . . . boring!
  8. #1 - SIGN A CONTRACT How to manage this socially 1) "Yes, I can do that, and I can give you a really good rate." A) if the baulk at having to pay, you can add, "Since you're my friend, I'm willing to give you a smoking deal. But since most of my business comes by word of mouth, if I didn't charge friends and family, I'd always be working for free. I'm sure you understand." 2) Whip out the contract, and either A) Have a printed hourly rate - say $100/hr - which you then cross-out and write $80/hr -or- B) You have a space to write in the hourly rate - you write in $80/hr. On your website, it lists your rate as $100/hr. Either way, they'll know i) they're getting a 20% discount to your customary rate ii) if they do comparison shopping, they're getting an 80% discount Now, you can play this like an auto dealer or a retail store. You may print your rate as $120/hr. But you never sell it for that - it's always "on sale" - and you "mark it down" to $100/hr.
  9. I used to be a lip biter. Then I would pick at the scabs. One day I decided it had to stop. Here was my strategy. First, lip biting/picking is often brought on by licking your lips because they're dry. So: step 1 - always carry a Chapstik. step 2 - while your lips are healing, also carry a small tube of vaseline. Use that in preference of the chapstik. Have a tub of vaseline at home - apply before bedtime and any other times your lips are dry or you want to pick. step 3 - As the lips heal, scabs and skin layers will come off. Rule: only remove this while looking in a mirror; get some tweezers so that you can be more "surgical" about it. Took me about 6 months before all the layers came off. step 4 - maintenance - use the chapstik when you're out and about; use the vaseline at home - and always apply before bedtime. Stree-wise, get a substitute - say a stress ball. Good luck.
  10. Doesn't sound like you've tried meds? Hypnotics like Ambien, Lunesta are sleep meds. You might also benefit from benzodiazepines such as Temazepam (helps to induce sleep), or Clonazepam [Klonopin], which reduces anxiety (and might calm your racing thoughts). Beyond that is trazodone - 50 mg is the path to sleep-land. OTC solution would be to take 0.5 mg of Melatonin 4-5 hours before your desired bedtime. Non-drug approaches would be: Learn and practice meditation. You meditate while to are in bed trying to induce sleep. Meditation will teach you how to control your thoughts and eliminate the racing thoughts. Bio-feedback equipment can be added to aid with this if necessary. A radio - listen to music or talk radio as you're falling asleep - this disrupts your own racing thoughts. Good luck!
  11. Ask your doctor about putting you on 300 - 600 mg of modafinil (Provigil), which is available as a generic now. Skip the nuvigil (still under patent - $$$).
  12. My mother has this saying - "the hungry dentist." A red flag is when you visit a new dentist and they find multiple cavities that need to be filled. Get a second opinion! I'm lucky in that I've been with the same dentist for 26 years and trust him completely. When he retires and I have to find a new dentist - if that new dentist comes up with 6 cavities, well, I know right away - "hungry dentist" - get the hell out of there!!! That said, post-dental pain/discomfort for a couple of days after a procedure isn't unusual. They've done great violence in there - it takes some time to heal. Now - cuts on the tongue and lips - that I would assume is bad technique.
  13. Try taking it 4-5 hours before your desired bedtime; 0.5 mg can be effective in resetting your sleep cycle this way.
  14. http://www.drugs.com/drug_interactions.html being one of those on-line checkers. That allergy med is pretty old-school. Chlorpheniramine is an older, sedating anti-histamine. Phenylephrine is a decongestant, used as a replacement for pseduoepedrine. Worth a chat with your pharmacist or doctor - they could recommend a replacement, single drug allergy treatment - such as the more modern non-sedating antihistamines (e.g., Clartin, Allegra).
  15. Try again on the trazodone. In general, if you type in "parnate" and "trazodone", an alarm goes off and a red flashing light starts spinning on top of the computer. But . . . that is for high doses of trazodone with an MAOI - the general concern being Serotonin Syndrome (not hypertension). Ironically, ask your doctor if she prescribes trazodone as a hypnotic for patients who are taking an SSRI - I bet you'll find she does it all the time. Now - who do you think would be more likely to have a serotonin reaction? For hypnotic use, you take a low dose of trazodone and there is research to back up its safety and effectiveness. Bring in copies of the research and give it to her. Ask her to consult with other psychiatrists and pharmacists - she'll find that the parnate + trazodone combination is used. Here are some links to get your started: Low-dose trazodone as a hypnotic in patients treated with MAOIs and other psychotropics: a pilot study. Management of monoamine oxidase inhibitor-associated insomnia with trazodone Pharmacological Management of Treatment-resistant Depression Antidepressants and Insomnia Finally, one case report of using Quetiapine with an MAOI: Quetiapine for Insomnia Associated with Refractory DepressionExacerbated by Phenelzine You can also try chronotherapy yourself. Two parts to this, which can be done alone or combined: 1) Take 0.5 mg of melatonin 4-5 hours before your desired bedtime. This works better in changing your circadian rhythm than taking it at bedtime, and high doses are not needed. 2) bright light therapy - get a light box (~15,000 lux) and use it for 1 hour in the morning. Then there are generic recommendations and cautions. Such as - don't use a computer for an hour prior to your bedtime: you're basically staring straight into a light source (and the blue light component is thought to be particularly effective in resetting your circadian clock). Of course, by typing this message to you, it's obvious I'm violating this guideline.
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