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Found 746 results

  1. "Best" as in being effective with fewer side effects. Which ones were the best for you? Which ones did you take? What condition(s) did you treat? What side effects did you get? How did the antipsychotics compare to "conventional" antidepressants? Can antipsychotics be an alternative to "conventional" antidepressants? What are the risks? What are the benefits? Do they make you a tomato with time? Psychiatrists prescribe them more often in recent times, it seems.
  2. Have a strong itch to drop Effexor...(I won't go cold turkey). It stopped my dysphoric crying spells, but now, 10 months later, I'm feeling increasingly flat, apathetic, numb, no motivation (even after dropping to 75mg). I hate how all A/Ds have this lobotomy effect on me longterm. It's initially fine in acute episodes, I'm not sad now, but I can't function properly, and I continue to score Moderate-Severe on the depression scale. I think it's counteracting my Ritalin (which I increased to 30-40mg)? I don't want to increase Effexor above 150mg, I'd never be able to go off. I'm trying dosing at night instead, will this make any difference @mikl_pls ? I skipped yesterday's morning dose (then came the intense nausea, over stimulation & brain slosh awfulness @10 hours later) and I took my dose with dinner. I'm seriously considering going on low-dose mild SSRI instead (Prozac?) I'm sensitive to meds & side effects, and I'm also VERY worried about withdrawals. Especially from Effexor, they are the WORST, and I just read study that Effexor withdrawal syndrome is not dose-dependent: https://www.researchgate.net/publication/7402189_Venlafaxine_and_Serious_Withdrawal_Symptoms_Warning_to_Drivers https://metro.co.uk/2018/01/24/woman-shares-coming-off-antidepressant-ruined-life-7255570/
  3. Forgot to take Lamictal yesterday (I took my other meds). Holy Hell, I took my dose today (on schedule) and I STILL feel awful!! I've only been on 100mg....I thought Lamictal had a super-long half-life? Yesterday went like this: 10am - up, had breakfast 11am – slight Brain “swishes” started (was out the entire day) 12pm – Stronger Brain zaps start 1:30pm – Lunch (meat, salad/veg) 2:30pm – Sudden extreme exhaustion 4pm - more brain zaps => ZAP ZAP ZAP! 🤯 7pm - Irritability starts 11pm – Tea, bedtime, could not fall asleep (I haven't had insomnia in 2+ years) ...Night sweats…Restless legs..... 12am – Ruminations, feel weepy ..Insomnia ensues…(Toss & turn, sweaty/achey all night) It's now 12pm,and I am STILL having brain zaps! I worry I’ll never be able ever taper, switch from, or withdraw from this med. You probably think well, with MI, WHY would you ever go off it? For me, longterm, these meds are band-aids. There is always a price. Ok, maybe great at preventing acute/severe depression, but as a result, they rob me of any spark, joy, elation, happiness, libido, sexual sensation/response, feelings of reward, love.... This disturbs me. I used to know what positive emotions felt like… So I’m stable, existing.....but still lacking will or any interest in living....
  4. Good God, my habitual oversleeping is worsening.....I literally cannot get up before 11am. I know this is probably due to the fact that yes, I'm depressed and do not have anything of purpose at the moment to wake up for.....PLUS winter weather that's dark as Hell.....PLUS on a stupid stimulant break, until I can get in to see pdoc in 5 days. Are there any other tactics you've used?? I'm going to bed same time every night (by 11pm). I sleep really well entire night. WTF. I tried a sunlamp thing in the past and it made me headachey & irritable. Even when I go for walks during the day, it doesn't help.
  5. Starting this thread because boredom, idleness, lack of stimulation is often a key trigger of depression and bad habits. When I get bored, I feel an emptiness, uselessness and physical/mental lethargy, cue ruminations, then I sleep excessively. This isn't always fatigue: It's an automatic (and very negative) avoidance behavior. This link lists 150 ideas (from high effort to minimal effort - from "fun" to mundane) in order to build healthier habits. I need to stop waiting to "feel good" before taking any action. Any thoughts? https://www.developgoodhabits.com/what-to-do-bored/ Today, I: Journaled, Cleaned my desktop, Backed up computer, unsubscribed to some junk email, Did some stretching, called a relative, dealt with an admin issue, read some blogs about depression, provided some words of support/appreciation for someone.
  6. Any opinions on parsing out differences between these, and treating each each symptom? Is this still depression? Is my brain rendered dysfunctional without stimulants now?? I have chronic depression (dips down here & there), but then it always goes back to this level (nearly a baseline for me). I'm tired, blah, SO LISTLESS and all I want to do is lay in bed all day, comfy & nice. Today, I managed to go out to get groceries (was out of TP for crikes sakes), showered, then back to bed resting & staring at wall. No interest in listening to music, trying to read made me drowsy.... Not sad, not thinking of anything... just lying in bed, with no wherewithall or motivation to get up. Other factors: Winter weather, I've been on Ritalin break for 1 month.....Problem is, the last month on holiday, I was fine, active, good mood and had energy!! Blood tests are all normal. What gives?
  7. I am so very lost, angry, hurt, depressed, explosive, and drowning. I was put on latuda or my bipolar and depression acting up... I hate new meds for this reason. I started having my ptsd dreams again, ate everything in site and craved sugar omg terribly, have been depressed, cant color which i love to do, just wanna sleep, explosive anger, crying jags, hate life, nothing makes me happy, everything just sucks. Im so angry cause i feel like i did before i went on any meds, 20yr ago. Im so confused i just feel like im grasping at air.. I was in the er the other night and they basically sent me home after giving my dose of larzapam i didn't take in the afternoon cause i doesn't help. My theory of it is it didn't help before the latuda what is gonna make it work coming off latuda or after off.. I remember why i drank now.. I didn't need to feel this then.. I want to drink so bad and wont cause I've been clean 6 yrs April will be 7 and i worked to hard to get here and refuse to prove others right. Im so so messed up i cant sleep cant watch TV cant color yet dont want to do any of the above either but if i dont sleep i hurt... has anyone felt this way.. It sux cause the battle to find meds to work will start tomorrow cause my liver doesn't process meds it flushes them out.. oh well sorry just needed to vent and hope someone can help
  8. Ever since I was young I've always dreamed that I'd end up becoming rich and famous and become a well known celebrity or something. There's also other things that I dream that I could be like, such as being really beautiful and going on magical fantasy adventures where I travel to various places and stuff. But the real world is a piece of shit and it's very likely that will never be the case. I'll never live in a mansion and be so famous that people make biographies and documentaries about my life and the things I've done that made me famous. I'll always be hideous and I'll never go on some fantastic quest or anything of the sort. I'll die without having accomplished anything meaningful. Because I can't be things that I want, I don't like myself and see nothing good about myself. People try to convince that I'm not worthless and there are good things about me but none of those things really help anything in the end. I can't feel pride in them because I don't have the things I mentioned. I can only like myself if I live the life I've laid out above. I don't want to be anything else and can only feel truly happy and satisfied with my life if I'm like that.. What can I do? Is it possible to like myself despite the fact I'll never be who I truly want to be?
  9. Hey I'm an aspiring writer struggling with motivation due to my depression and I keep hearing about various other writers, some of whom are famous still being able to keep up a decent work ethic despite of their disability. How do I become like them? Does anyone here got any advice?
  10. My depression hasn't been severe lately. Mainly, I struggle daily with lingering apathy, lack of interest/motivation and low level depression (normal for me). I've noticed lately, in trying to complete work/studies and meet deadlines, I've become more & more avoidant, procrastinating. For example, today I'll do everything EXCEPT focusing on any work/undesirable tasks. I slept in, didn't even shower...went online, spent HOURS searching for a particular kind/style of shoes, ordered random supplements...All things that are not important! I've even put off buying much needed groceries, laundry, going to the gym...and take afternoon naps instead. Is this depression or am I just a sh*t lazy person? I feel really guilty about it. I need to constantly waste time in order to do like 10 minutes of work before bedtime! No intrinsic motivation...I really don't think this warrants adding meds, I want to be able to push through. Can anyone relate or have any suggestions? Other than just brute force?
  11. I know it's not a competition in any way, with illness. But had a surprise when a friend messaged me to ask how I was doing. I replied &thanked her, said it was really nice to hear from her (particularly because I've been lonely, isolating myself, depression, etc). She literally responded with "Well, I got cancer so I'm sure it's worse than you..." That's all she wrote, no elaboration. What would you make of this reply? I'm empathic, and assume she's hurting or afraid. (btw I don't know if she still has it, or successfully treated already) I literally had no idea what was going on and I gave her support, told her I'm here for her for anything if she wants to talk, but in a way, I feel hurt, because of the way people with illnesses always "one up" and diminish each other, like experiencing one type of illness, trauma or pain is much worse than another?
  12. What has been your experience with Wellbutrin? Pros and cons? What does make Wellbutrin different from other antidepressants? Does it stop working after a while?
  13. I've been experiencing depersonalization frequently recently but I don't understand why. I probably don't fit the criteria of depersonalization disorder so the only other reason I could experience is if I used a psychedelic substance, which I do not. I've been wondering if depression is the cause of the depersonalization as it often, but not always, happens during MDD episodes. Could this be correct?
  14. Because of my depression, I like many people, have pitifully low self esteem. Ever since Iast year I been having a tendency to daydream of having a better life and various other powerfantasies I make up. When daydreaming my self esteem skyrockets and I feel good. But I kinda resent it because I hate vanity and I'm worried that having super high self esteem will make me arrogant and vain and grandiose. I also begin to kinda lose touch with reality and think that I'm above the rules and stuff like that. I'm worried about becoming egotistic. I had a debate about this 2 days ago with my therapist and she said that the daydreams aren't bad because it's better than having extremely low self esteem(paraphrased). I disagreed. So with all this in mind, is it an adaptive or maladaptive coping mechanism?
  15. My mood has been absolutely deplorable for the past month or so. I honestly don't know how to begin to describe how bad it is. I have a lot of the "negative" symptoms, a profound deficit of positive affect. Nothing in life gives me pleasure, suicidal thoughts begin to surface, and I sometimes descend further into psychotic depression. These are my depressive episodes. I don't know how else to paint the picture more thoroughly because I never know what to say, and it really bothers me when I'm like that when I'm around my boyfriend. I want to talk, but I can never think of anything to say, so I rely on him to start conversations. I don't get it... Dopamine has been posited to be a central neurotransmitter in the pathenogenesis of anhedonia, and I'm on multiple meds that supposedly on their own and in combinations with other meds I'm taking can treat anhedonia. What am I missing?? I'm on Dexedrine up to 60 mg as needed, Vyvanse 50 mg, Wellbutrin 200 mg, Viibryd 40 mg (increases dopamine via postsynaptic 5-HT1A receptor stimulation), Vraylar 3 mg... What else could possibly help? There's no relief in sight when I'm like this.
  16. So I joined this forum to talk about my various mental health issues and try to find a solution or two with people who can relate. I been diagnosed with autism, clinical depression, and oppositional defiant disorder at various points in my life and I'm currently 16 years old at the time of this writing. I hope to have a great time with you guys.
  17. How do you distinguish between the Obsessive thoughts/ruminations that are due to depression and the "pure obsessive" type thoughts that are considered OCD? I know that you don't have to be compulsive to have an OCD diagnosis (I think) but more & more I see my obsessive, negative ruminations taking over and I wonder if this means I have both OCD and Depression? My brain just gets stuck on a track loop....any sad trigger and I start having related obsessive thought patterns and I cannot escape the resulting mood/emotion that comes with it.
  18. I was on Olanzapine for about one year and during that time I did excessive spending which may have caused lowering impulse control and consequently am now in bankruptcy. Have been off Olanzapine since December, 2018. In March went on Seroquel and experienced manic situations, where I was out of control (never had this happen to me before). I became excessively hostile towards a clerk in Walgreens, reduced my veterinarian to tears and alienated alot of my neighbors by my raging. We upped the Seroquel thinking I was having my first manic episode, it only made everything worse. Since coming off of Seroquel in last two weeks, I am now calm and the urge to act out aggressively is gone and I am mortally embarrassed about my behaviors. New psych doc now, former one retired. Started Reluxti two days ago at .5 mg. First day experienced some brain zaps and thinking it might have been due to the mixing of recently going off of Seroquel and introducing Reluxti. Today, no brain zaps. Taking Benadryl to help with insomnia as Rexulti may become stimulating. I know this is a very expensive drug and being on Medicare I do not qualify for any of the manufacturer's savings plans. My new psych doc believes he can keep me on his extra supplies forever or until they go generic. I am worried about being on this drug and loosing him as a psychiatrist and ending up with a co-pay of $400.00 a month and ending up in the Medicare Donut-hole very quickly. The trial pack he gave me has a 14 day supply. I recently did a gene study thru GenOMind. I am an ultra-rapid metabolizer and subject to many skin issues. When I first saw him, he became very frustrated with me and didn't believe me that I can't tolerate most of the behavioral meds out there but once he got the gene study, he then understood. The only drug he would suggest is Rexulti. I am in a quandary as to what to do about going on this very expensive medication with no way of paying for this and getting stuck on this drug should I loose my new psych doc and his many samples. Purple
  19. Hi all, I'm a 20+ year sufferer of extremely TRD and am trying LSD (1P-LSD, more specifically) microdosing to help lift my mood and combat anhedonia. I'd love to know if anyone else has tried this. Specifically: what was your regimen? e.g. every 3 days?, dosage, substance, method did any initial beneficial effects increase over time? if so, over what kind of period? did you develop a tolerance? did it help with your anhedonia? did you try more than a microdose e.g. 1/4, 1/2 or even a whole tab? If so, how was that therapeutically? FTR, I'm taking 10ug (1/10th of a tab) every 3 days using the volumetric method. I felt notably more energetic and less severely depressed within an hour of dosing. This persisted for ~ 14 hours. I couldn't sleep. Now, the next day, I feel kind of back to normal (i.e. feel very depressed and anhedonic), which is very demoralising. Thanks, Pete
  20. I've been relatively stable with a few jags here and there for almost 2 years, and suddenly I'm experiencing some depression that has me in tears at times, as well as anxiety that results in panic attacks so bad that I feel like I can't breathe. I'm very emotionally labile, reactive to any trigger, sending me to seclusion with my depression. The only thing that has changed is that I swapped Dexedrine to Bontril-PDM for my weight management (and with Bontril-PDM, off-label ADHD management, idiopathic hypersomnia management, and treatment of refractory bipolar depression). I'm thinking this may be the trigger, but I needed to take a break from Dexedrine because my receptors were too desensitized to it and I was starting to gain weight, sleep all day, become very inattentive (like almost having wrecks kind of inattentive), and feel a little depressed. So I may have identified my trigger, but I need to take a good break from Dexedrine so when I resume it, it will work as it did when I first started it. My question is how does one prevent depression (neurochemical, not cognitive)? Is there something that can be temporarily added to my cocktail? I see my pdoc Friday. I have tried lithium and it causes seizures. Depakote makes me a zombie. Lamictal causes horrendous acne. I'd rather not add a second antipsychotic. Increasing the antidepressants seem to do nothing. Should I just get back on Dexedrine ASAP? Or continue to give it a break and try other alternatives? I thought about trying Ritalin again, but a much higher dose than I've tried before, like 40-60 mg in Metadate CD form (the only form I felt anything from with methylphenidate). Concerta and regular Ritalin are useless, and I've heard bad things about Ritalin LA. Any responses or insight would be much appreciated! Thanks in advance!
  21. Hello all, I'm looking for some med experience/anecdotes! I am bipolar and also have anxiety, ADHD, and PTSD. Currently I'm taking Lamictal (400mg/day), Geodon (80mg/day), and Adderall (25mg/day). I'm looking to change it up because I am seriously struggling with the side effects. Since starting Geodon I am tired all the time (it doesn't help that I'm in the midst of a depressive episode) and I've gained 20+ pounds in two months. I think it's helping with the manic side (or maybe that's just because of the depressive episode I'm in?) but I can't deal with these side effects. The Adderall works great for my ADHD but I think it's making me too edgy/irritable for my liking. On top of it I have been having terrible anxiety lately. I'm meeting with a new PMHNP next week and I like to research my med options ahead of time so that I feel more informed and can advocate for myself. I'm interested in Wellbutrin because it doesn't have weight gain associated with it, it helps with binge eating and supposedly helps you quit smoking (both current concerns of mine), and can work for both depression and ADHD. I'm also interested in Buspar as a possible anxiety med? I like that it also isn't associated with weight gain and that it isn't supposed to be sedating. I've also taken Abilify in the past (before I took Geodon) and didn't experience any terrible side effects other than it making me sleepy but maybe combined with the right thing that wouldn't be as much of an issue? Anyone have experience with this combo or a similar one? Any and all feedback appreciated! The med game is so overwhelming.
  22. Hoping someone can offer some insight to what is happening with me? I've been taking Ritalin consistently over a year again. Pulled me out of a bad anhedonia - I'm focused, motivated and goal driven. Mood was great the last 5 months. Now, I'm having intense meltdowns in the afternoon/eve. Stress-related. Internal pressure to succeed. I've lost many years to depression, being unproductive (was even bed-ridden from episodes).I've worked REALLY hard to pull out, and had one of the best 5-month "good periods" in a long time. I'm afraid of going back to that... I wonder if the Ritalin is in fact causing mood swings now. I get crying spells: stress, perfectionism, anxiety, irritability. I know everyone here will probably suggest adding an antidepressant again, but to be honest the A/Ds increase my apathy and anhedonia (I have Double depression - chronic low mood/no pleasure, with intermittent severe episodes). I don't know what to do, this seems to be stress-related as I've been so focused on Ritalin and wearing myself down. My main coping mechanism lately is studying, reading, working, writing as much as possible to distract myself from my unrelenting unhappiness with my life and myself. Basically, nothing is fun or enjoyable for me, I can't enjoy going for walks, hobbies or even watching tv series. I think the Ritalin has motivated me (good) but I've become a workaholic robot who only gets satisfaction from output, accomplishing goals and achieving perfection. I feel like a complete FAILURE if I'm not learning or working the entire day until bedtime!!! Is this similar to a Hypo or "Mixed" episode?? I don't want doc to label me as Bipolar and then quit prescribing Ritalin.
  23. Hi guys, So I've been depressed and have had severe anxiety for 3 years. Antidepressants make me hypomanic (kinda) and triggers unstable mood. I don't fit in the usual description of bipolar, but there is definitely something not right about the way i react to antidepressants - feeling high, warm, racing thoughts x 100, gets overly chatty etc. I've tried the following moodstabilizers Lamotrigine (disaster) Trileptal Gabapentin Abilify (made me hypomanic) Seroquel (made me hypomanic) Depakote/valproate (still taking) This depression is killing me, but my p.doc. won't prescribe me lithium. Tried two different doctors. What are your thoughts?
  24. Hi guys, So I'm withdrawing from Gabapentin 900 mg. I'm down to 300 mg every second day. About a month and a half ago I tried going from 300 every day to 300 every second day - skipping a dose every other day. At first it went just fine, but then at the second week mark i started getting really depressed and began crying all the time. I then went back up to 300 every day and I started feeling better again. Two weeks ago i went back down to 300 mg every other day, and again the first week was fine, but now I am experiencing the same thing all over again. So - I know this is a popular question - but is this just withdrawal or is it a relapse? I am not otherwise experiencing any other symptoms. Has any of you gone through gabapentin/neurontin withdrawal? And has anyone else experienced this pattern? I am taking it for bipolar disorder NOS and anxiety, but it hasn't really helped that much. I am also on Mirtazapine and Depakote
  25. Hi everyone. I’ve been dealing with unbearable symptoms for over 4 years. Insomnia, racing thoughts (OCD), derealization, irritability, brain fog and depression. I have tried so many medications, but none help. My insomnia and anxiety are through the roof and I have 24/7 derealization. Years ago, 2007, when I was struggling with depression, my psych talked about starting an MAOI, but we instead we added geodon to Zoloft and it worked (for awhile) Long story short, I developed sudden onset ruminating thoughts (in form of OCD), insomnia and Anxiety in 2009. After many trials of meds (I’m adverse and paradoxical to most) I finally was put on remeron which got me sleeping again and in turn helped my other symptoms. From 2010-October 2014 I did relatively well, that is until remeron stopped working and all my symptoms came back. Since I have been inpatient several times trying every sleeping med , bipolar med, SSRI etc with no relief. Mom wondering if an MAOI could help me? Can MAOI’s treat anxiety? Racy brain? I’ve read they can make insomnia worse, which I don’t need. Symptoms: severe insomnia, lucid dreams/nightmares, 24/7 derealization, severe anxiety and panic, major depression, brain fog, dizziness, migraines. I believe, like in 2009-2010, many of my symptoms are from sleep deprivation. I am very desperate to get control over my anxiety and sleep. I’m at the end of my rope. Could an MAOI help me as a last ditch effort to get some kind of quality of life back? Current meds: weaning off Zoloft, weaning off remeron, geodon 20 mg X2, Ativan 5 mg per day (please don’t jump down my throat about this, it will give me a panic attack. I know it’s a high dose and I need to taper this too), prazosin 2 mg. TIA
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