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Found 15 results

  1. I know it's not available at the moment but I believe it was at one point in Europe - does anyone have any experience with it? It's part RIMA and part SSRI, which shouldn't work but does
  2. There is a certain irony here: "Ugh, tricyclics! Low selectivity for the serotonin transporter over the noradrenaline transporter, and what's with all the antagonism at histamine, alpha and 5HT2A receptors? Dirty stuff! Thankfully this is the 90's, and we have Selective Serotonin Reuptake Inhibitors!" "...eh, maybe you do need a bit of a noradrenaline boost on top. Thankfully this is 2000, and we have SNRI's!" "...and maybe it would be nice to have some histamine/5HT2-antagonism-mediated anti-anxiety action, too. It's 2010, try some Seroquel or Mirtazapine on top of your antidep
  3. Hello Comrades, I've been taking Sertraline (50mg daily) for 9 months now. Reason for taking Sertraline: Depression & SAD. Maybe some GAD. So Sertraline treats my baseline anxiety quite well, also got rid of digestion problems, but I am struggling with side effects: Motor restlessness, agitation. I've always been quite "hyperactive", but Sertraline has worsened it by a good amount. I cannot sit still, I feel I have to walk, to pace. I move my fingers and toes to "release" some of the energy. Also lots of fidgeting, rocking back and forth. I have the urge to crawl out of m
  4. Anyone have experiences on the reversible-MAOI Meclobemide (aka Manerix)? Apparently it’s not in the US (but in Europe, Australia & everywhere else). I cannot seem to get much info on this drug but from Wikipedia - seems like a promising choice for someone that has gone through most all the SSRIs, SNRIs, A/Ps etc. On (Wikipedia): Of 2300 people in multiple clinical trials who were treated with moclobemide in doses up to 600 mg with no dietary restrictions, none experienced a tyramine-mediated hypertensive reaction.[60] Moclobemide is tolerated to a similar degree to the SSRI
  5. Just a poll to see what your take is on MAOI's or TCAs (for Depression)...which do you prefer, and WHY? Both are not the 1st line of treatment (says my pdoc) she is hesitant to suggest either, but i have not tried either class. Is one or the other more helpful and are they worth the side effects? (I've heard both have pain-in-the-butt side effects but why not try)
  6. I'm currently on the Emsam 9 mg/24 hr patch plus Adderall XR 40 mg to potentiate it, and it doesn't seem to be doing its job at all. I am completely anhedonic, find no pleasure in doing anything I used to do, and my friends and family have even noted that I am quieter and don't talk much at all anymore. What's strange is that I also seem to randomly snap at people for no apparent reason from time to time (which I don't even see coming, and it happens very seldom, but enough to be troublesome). I must confess that I've resorted to wearing two 6 mg patches to get 12 mg for a few days at a time,
  7. Anyone been on Nardil or other MAOIs? I'm not real excited about the diet and potential side effects but I'm willing to try anything at this point. I've tried tons of ADs, AAPs, mood stabilizers, just about everything except tricyclics, plus a failed round of TMS. Really hoping Nardil is the answer. any experiences or tips are appreciated!
  8. Hey all, had a rather upsetting appointment with my psychiatrist and wanted some advice please. Saw my psychiatrist who showed me a letter he wrote to my gp saying basically given my knowledge of antidepressants and having an opinion of what antidepressants I want to be prescribed that he suspects I might be doctor shopping, not being honest about what medications I am taking and wants to call the doctor shopping hotline to check my prescription history and wants a blood test to test for recreational drugs. I'm still getting over the shock but key points; Have not taken any recreatio
  9. Hi. I am about to start MAOi treatment next week. Could you please advice me on: Texturized Vegetal Protein (soy meat) Not fermented. MSB (glutamate in all form and shapes, including maltodextrin, hydrolized protein, etc) Sweeteners (Aspartame and company) I have several low tyramine diet guides, but they often contradict each other in a point or another, like peanuts, chocolates and avocados. I wish there was a FAO guideline already! thanks for your help, guys!
  10. Hi everybody! A while ago I asked about switching to MAOIs from tricyclics. I ended up switching from imipramine to clomipramine instead with (surprise!) no results. Now I'm actually making the switch from clomipramine to Nardil/phenelzine. I just wanted to know of anybody who has been on Nardil, what side effects they had and how they found it, especially those suffering from severe or treatment resistant depression. I have a history of serotonin syndrome which worries me a bit but I'm going up slow (15mg a week) with a seven day washout. Hopefully, since my SS is usually caused by combin
  11. Hello all! I have 'severe' treatment resistant depression? I'm currently on 225mg of imipramine with 30mg of T3 (thyroid) for augmentation. After six weeks of waiting I had two weeks of bliss where i was 'cured' but then it just failed to settle. Unfortunately I've been having huge problems with anxiety and panic attacks. The only way I've been able to outrun these episodes is to increase the imipramine to this high level but I can't go any higher than 250mg. Has anyone else had problems with imipramine/t3 and anxiety? I see my pdoc Tuesday and he wants me to shift to a MAOI. But to do th
  12. i'm looking for ideas for a sleep med that doesn't interact badly with parnate. i can't take seroquel anymore (screaming in my sleep), and melatonin or benzos don't work. i've tried some other AAPs before with bad prolactin effects so those are out, except abilify, which is activating for me (but maybe there are some i haven't tried and didn't think of). pdoc was kinda stumped about what else to try (she isn't my regular pdoc, mine is away for several months). so i thought i'd do a little research myself to see what kind of options i have. she turned up her nose at trazadone, i'm not s
  13. Hi, Recently I have read about a combination of Nardil and Bioperine (regarding the problem with the current version of Nardil and its absorption into the bloodstream): "Nardil was changed in late 2003, due to a complete reformulation by Pfizer, who removed many of the excipient ingredients, including the hard coating. It is possible that the current version is not surviving the stomach acid content and therefore not as much is being absorbed into the bloodstream." I wonder, if anyone here has tried this combination yet ? and if so, Have you seen any improvement in regards to Nardil ?
  14. Hi, I have bulumia which I can reasonably control, some general anxiety - also not too bad but I've had trichotillomania for several years & now it's really bad. I've tried two SSRIs Zoloft & Lexapro 50mg & 10mg but the nausea side effects of both were so bad that I couldn't keep taking them as they were causing a serious bulumia relapse. I am seeing the doctor soon & the two main side effects I cannot deal with are nausea & weight gain. Is it worth trying any of the a-typical anti-psychotics as the seem to all cause weight gain? I've tried Seroquel 25mg and it just
  15. I'm looking for some advice. I've had a lot of experience with different antidepressants, and almost no success. I'm getting pretty tired of the whole trial-and-error process, and I'm not terribly confident in my doc's ability to prescribe the right thing, especially considering some special circumstances. Here's my history. I have been diagnosed with social anxiety and dysthymia. I've had both as long as I can remember. My first experience with taking antidepressants was Paxil when I was 16. This actually seemed to work well, cleared the anxiety and depression right up. I eventually tapere
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