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So, I'm bipolar, type 2. I tend to live in depression and only occasionally get the kind of manic you could replicate with a good caffeine high. I've been on Sertraline for over a year. I can't actually remember how long. I'm currently at 150 mg once daily, and I have been since October of last year. I also take Trileptal, recently reduced from 300 mg twice a day to 150 mg twice a day at my request. I requested the decrease in Trileptal because my pdoc said that it was the more likely cause of my persistent brain fog and exhaustion. I've been on that for a long time. 4 years? 5? Around there.
Both are second-generation SSRIs, both exhibit minimal drug interactions via Cytochrome P450, both are the most prescribed SSRIs and are considered first line antidepressants. Who's been taking both and what were your experiences? (How did they compare to each other?). I am looking forward to read your experiences... Which one did you like more?
Sertraline standalone makes many people somewhat apathetic, indifferent and unmotivated, and that's why doctor Gillman suggests augmenting it with Nortriptyline OR alternatively taking Clomipramine standalone for the full SNRI effect... Did anyone here try both combos? I am getting back on antidepressants and not sure how to proceed... but if I had to choose, I would preferably go for one of the two possibilities.
My brief period (6 months) on Sertraline has been that it sapped my creativity and basically made me not want to do anything, not feel anything. I just sit at the computer and watch videos and occasionally walk around, or eat, or go to the bathroom. I just don't have any drive to really do very much of anything, except what is needed for continued survival. I don’t even want to watch movies and series! Is that normal?