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Found 9 results

  1. Before reading this, don't get my pdoc wrong, she's excellent, well educated, and a very compassionate, caring, and even loving pdoc. But she hasn't been the same since her husband passed away, and it has reflected in her prescribing habits. So at my last visit at my pdoc, apparently, she was going to lower my duloxetine (Cymbalta) dosage from 120 mg to 60 mg anyway, regardless of how I was feeling (I told her I had been sleeping all day, had been feeling drained, and had been feeling worthless...). She had been "threatening" to do that for months but apparently, this was it. But I expressed an interest in switching to imipramine (Tofranil) since I had heard it worked miracles for some users around here in bringing them out of their deepest, darkest depressions. She honored my curiosity, but I had in mind that she would give me enough imipramine to switch from duloxetine (Cymbalta) to imipramine... She just tacked on 60x 25 mg imipramine to start with 25 mg and then go up to 50 mg. Seems pretty low to me... So she has me on duloxetine 60 mg and imipramine 50 mg... it doesn't seem to be doing anything at all. As far as the duloxetine dosage lowering went, I had some 30 mg caps left over, so I added them to the 60 mg for 90 mg so it wouldn't be such a dramatic dosage reduction for a week, and I couldn't do anything but sleep all day but all the while have horrendous nightmares. I'm now on 60 mg duloxetine and still having nightmares, but I'm "recovering" from sleeping all day. In my signature it says I take the imipramine in the morning--I do that because it's actually stimulating for me and not sedating. Anyway... this is what I'm unsure about... I don't know if I should give imipramine more time, or if I should switch to an SSRI + desipramine (Norpramin), which I took about two years ago and did so well on but I gave up on it because she wouldn't let me have more than 75 mg and I needed (desperately) more than that. At the time I was actually on duloxetine, but originally I was on fluoxetine (Prozac) + desipramine which my GP prescribed (I had to go to him because I was doing so horribly and couldn't wait for an appointment for my pdoc). The idea was the SSRI + desipramine would create a potent SNRI-like effect, more potent than any of the SNRIs on the market. I'm thinking about switching to sertraline (Zoloft) (which I've done well on before) + desipramine for a SNRI-like effect. But I'm wondering if I even need the desipramine and if that would be over-medicating because I have a stimulant--dextroamphetamine (Dexedrine). Won't that give me some norepinephrine reuptake inhibition and release? I would differ to my pdoc but I'm wondering if she's starting to lose her edge? I don't want to switch pdocs though... I've gotten so close with her and trust her... She knows me. The office staff knows me... (well... most of them...) Any input and responses would be appreciated!
  2. Ok, so I've had PTSD since 2007 when I was still in the Air Force. My meds just aren't working right to me, and I'm having side effects from one of them. I'm on 1000mg Depakote ER, Cymbalta (I forget how much), and 3mg Risperadone (Risperdal). I was taking 750mg of Depakote and 6mg of Risperadone until recently...we're trying to take me off the Risperadone, so the pdoc is upping the Depakote. I see *a* pdoc in the afternoon (my normal pdoc had to cancel and I wasn't waiting until June to talk to someone...I don't like my experiences with the VA for the most part). Anyway, so the plan is to take me off the Risperadone, but I have a major concern...I'm already getting really, really irritable! I haven't really been getting *more* angry, but I still get really angry more often than I'd like. But the irritability is driving me nuts and feels like it's getting out of control, and I'm afraid it's starting to interfere with my work, and I work in a call center and they record and listen to the calls... I also have issues regarding the Depakote. I kinda need to stay on the Depakote because it supposedly helps with my migraines too (which are getting to the point where I'm getting ready to go back on Botox again), so coming off of it and switching to something different may not be an option...I'd want my pdoc to confer with my neurologist before making that decision so they can both make arrangements and changes if necessary. Anyway, I also have narcolepsy. The last time I was on 1000mg of Depakote I almost drove through a bush in the middle of someone's yard. Granted, I wasn't on the stimulant I'm currently taking back then (Nuvigil). But I have concerns that it could make me drowsy again. But like I can take percocet and benedryl and be wide awake, so who knows...I don't normally take pain meds, just when I get kidney stones, but when I do I have to take benedryl because it makes me itch. I'll let you know what the pdoc says tomorrow, but I'd love some input on ideas I can discuss with the pdoc on my next visit. I need something for irritability, depression, and anger (preferably no more than 2 meds), and if one of them could help with migraines too (like Depakote) that would be great...
  3. Hey, hoping for some advice on a new cocktail. I have treatment resistant depression with social anxiety. Have tried citalopram, escitalopram, desvenlafexine, mirtazapine, duloxetine, pregabalin, bupropion, propranolol, phenelzine, tranylcypromine, quetiapine over last ten or so years. The thing I have found far and away the most effective has been phenelzine but maois gave me bad postural hypotension to the point where my psychiatrist made me discontinue. I'm on combo of cymbalta and remeron now but the only effect is excessive sweating. Any ideas for what to try next? Thanks in advance.
  4. Hey everyone, I have a question. So me and my boyfriend both have ADD and he recently started taking meds again after a while. He is from a different city originally and previously never bothered to actually get a new doctor. He went to a local clinic and asked to be put back on his meds until he could get in to see a psych doc. Doctor said yes, prescribed him dexedrine for a month. He ran out and went back to the clinic to get enough to last him to his appointment later this month. This time though, he got a different doctor that mostly just treated him like a drug seeker and kept referring to dexedrine as speed. He wrote him a prescription for Wellbutrin, which he also takes, and for strattera. So I did a quick lookup online and saw that strattera is a norepiniephrine reuptake inhibitor. Okay, cool, I know why that would be useful for someone with ADHD.... But he already takes wellbutrin. Which is a norepinephrine reuptake inhibitor. Sooooo.... Why does he need two? Obviously my next stop was crazy boards, and I searched the forums for wellbutrin and strattera together and the search came up nada. Nothing. Zilch. And if no one on Crazy Boards has brought up the two together it makes me wonder what's up. Is the search function just wonky, or is this something that doesn't often get prescribed together because they both do the same thing already?
  5. Hi. Background-Diagnosed with progressively worse forms of depression since 2000. Current Diagnosis-Bipolar 2 Current Meds-Latuda 60mg, Klonipin 2mg, Concerta 54mg, Wellbutrin XL 300mg My Current Situation-went back on Lexapro for a month in June. Worked ok but caused major sex issues and being that I remarried in January and my husband already thinks I'm lacking something in bed, it had to go. Started with 150mg Wellbutrin in July and felt so bad (depression) that I called the dr and they upped the dosage early to 300. 300 makes me feel ok...for about four hours. After that I'm a varying form of a train wreck for the rest of the day. It honestly runs out of my system like Ritalin out of a kid. My dr wants to try some newer med but I am already WITH insurance paying out the ass for the Latuda. I actually miss my "manic" episodes because I am never happy. Additional Info-Two sons and a stepson ALL with ADHD and my oldest son also takes Zoloft for Mood Disorder NOS. My husband's first wife committed suicide with a healthy handful of Zanax and painkillers. I am positive he's depressed too but he refuses to take anything which doesn't help. I've been on almost every one of the popular antidepressants. Most of them helped-for a while and then they quit working. I go back to the dr in about 2 weeks IF I can make it that long. Any suggestions that don't include secretly drugging my husband or sending all of my children to boarding school? In other words I'm looking for med help...
  6. Since my initial diagnosis of type 2 bipolar disorder, I've been on a lot of different medication. I was initially started on Klonopin and Lamictal was added shortly after. I've been hospitalized 4 times for suicidal thoughts. I also have GAD and PTSD. Here's the current cocktail: Lamictal 200 mg QAM Seroquel 25 mg BID Wellbutrin SR 150 mg BID Seroquel 200 mg QHS Buspar 15 mg TID I'm also on Verapamil 80 mg TID for migraines. I was taking Lexapro 20 mg but I ran out about a week ago. I can't tell what is or isn't working, although I feel relatively stable. I just don't want to be on so many meds. Of course I'm also conveniently in between pdocs and can't get in to see my old doc until early June. Help or advice?
  7. This is my second post since joining. I am looking to find out any info about what my combination of meds is doing inside my brain. Look at my introduction post if you want to know about my condition. I am now prescribed venlafaxine 150mg in the morning, mirtazapine 30mg and quetiapine fumarate 150mg at night, with clonazapam 2mg PRN. I know how the venlafaxine and mirtazapine theoretically work together to boost 5ht and NE "California Rocket Fuel". I know that since i'm only at 150mg Venlafaxine it is only acting as a SSRI, but i think i probably will have to increase to 225mg soon, changing it to SNRI. My question is what is the quetiapine fumarate 150mg going to do? What are its affects going to be upon 5HT NE DA systems as an adjunct to the "California Rocket Fuel"
  8. I am hoping this is some of my useless over planning, and that my pdoc has an easy answer, but.... I am going in to see my pdoc (*mine,* hallelujah) on Tuesday. I am still extremely depressed. Flossing, brushing, and rinsing was the big accomplishment today. I am hoping to talk myself into the shower tomorrow. I am maxed out on Lamictal (400mg) and Wellbutrin (450mg). Because of my kidneys, I have had to cut back my Lithium to 300mg, at which dosage I had a .4 level before. The lithium may have to be ditched altogether, depending on what my next creatinine level is (it has been rising rapidly). To be honest, I think it *is* going to be ditched, and if it isn't, 300mg is just such a tiny amount, and such a low blood level, I don't know if I am going to be left on it. I feel like the benzo part of the cocktail is okay, I have been using them a little more during this last awful month, but appropriately. My pdoc always tells me that I am too cautious with my PRN, but I am really using it at the moment. I had trouble with Geodon. This last time I had trouble with the risperidone, but it was apparently interacting with the lithium. Last year, risperidone was amazing in the midst of a mixed state, but I got kind of sick of it when things calmed down. Gah. Anyway. What next? I know there is no answer. But I don't even have any idea of what to think about doing next. He is always open to my suggestions, and always willing to tell me no, which is what he is there to do. Do I stop the Wellbutrin? Do I add an SSRI, and keep taking the Wellbutrin? Should I think about looking into another mood stabilizer? If I do go off the lithium, would it be reasonable to think about AAPs? BUT, my pdoc seems to dislike using them, and particularly doesn't like Seroquel; this is possibly a department-wide prejudice, because the covering pdocs have always said they don't like it either. I feel like I am forgetting major things, too, ideas that I have suggested to other people in the past. So basically, this is really speculative, but I would like to have some ideas to offer when I see him; I have never had so little idea of the next possible step, and I want to try to research some stuff before I see him on Tuesday. You can see what I am taking and what I have tried in my signature. Anyone? Thanks for your help.
  9. Okay, in my posts, I have been referring to my depression since July of 2011 as moderate. I thought it was moderate, which I knew still meant I was depressed. But compared to episodes I experienced in my 20s and early 30s I knew what *severe* depression felt like, and this wasn't it. Then the mixed episode was triggered about 3 weeks ago, and kablooey, and I don't know how much longer I can cope. Then I saw the stupid covering pdoc (who I do. not. like. She is condescending, and I am smarter than she is (not about psychiatry, but in general). Another thing I like about my pdoc is that he is clearly at *least * as intelligent as I am, probably more so. It is a relief sometimes to be able to use my real vocabulary. Anyway, she saw me yesterday and said, "Well, you aren't mixed anymore, you are depressed." And I realized she was right. For one thing, I was sitting there wearing a dirty shirt, dirty pants, a hat to cover my greasy roots, and a barrette to pull my hair back. It wasn't until later that I found about a third of my hair had never been in the barrette, and was just hanging there. And I haven't showered in over a week. And you know what? I just don't fucking care anymore. I'm tired, I don't have time for social niceties. But I realized later that it was the first time since I started going to this psychiatric unit that I had gone in looking really disheveled that. I see her again on Friday. Then I have an appt. with MY pdoc 11 days late. But if this is still this messy after Friday, I am going to call to be on the cancellation list. I am eating way too much. Which is a symptom I have had when I was severely depressed in the past. So I guess I've crashed, and hard. Mixed states are the closest thing to mania that I've experienced, and I was definitely mixed for a couple of weeks there, but this past weekend I seem to have crashed. I want to say Monday. And I feel like this is a big one, this is not going to be "moderate." I can feel myself being sucked down the hole. Oh my god, I was so sick in my 20s and early 30s, I do not want to go back there. I don't know how to cope with DH, and vice versa. Gah. i can't think straight. Now I am no longer weepy, which to me implies over-reaction, Instead, I am now constantly crying. It is my default emotional response, it has no bearing on the situation at hand. I am praying that I am being dramatic, and there is a lot more tweaking we can do with my current cocktail. But I think something major is going to have to happen, like coming off Lamictal or Wellbutrin. Or maybe add another AD? I don't know. I don't want this to happen, but I can't thinking about it. sorry if this is a mess. I am really tired, but not sleepy, which is another hallmark of this episode. I know this is going all over the place. I hate being crazy soooo much.
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