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I know there are some amateur pharmacologists here... a question along the topic of neuroplasticity. I've heard that chronic use of antidepressants can eventually "downregulate" your receptors (Serotonin I'm assuming) so that if you ever come off the drug, your brain will never be the same as before, it will never function the same without the med, because your brain adapted/changed due to the medication (or become dependent to function in some way)... I'm wondering if the same thing happens with Stimulant drugs? I'm aware that tolerance builds up if you use them everyday for a year or mo