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So Effexor XR is the best medication I've taken for my problems which combined anxiety disorders, panic disorder, and obsessions. It has also helped with depression that inevitably follows these... So I know the SSRIs/SNRIs are notorious for this side effect, I was just wondering how other users deal with this problem as this can be difficult to talk about with peers and even doctors? I don't even like posting this here, I just don't know what to do. I was on Effexor XR for about 5 years at 300mg, last year I came down to 150mg, and currently I'm on 75mg. Luckily I've felt pretty stable and been maintaining well. However, my libido has been transient and pretty much nonexistent at times. I've tried several things, from abstaining for weeks at a time to OTC libido boosters....Oddly enough I felt my libido was actually higher on high dosages of the Effexor. Possibly to do with the Norepinephrine/Dopamine push? Anyways I asked my Pdoc about it finally and he said he script me Viagra or Wellbutrin. Neither of which I'm very fond of doing. I have a bottle of Wellbutrin sitting on my dresser right now that I haven't started yet because I've heard it can make anxiety issues worse and the fact I could be adding another side effect (truthfully I don't want to start another medication and go through that again) The Wellbutrin is a last resort right now....I don't feel like I should be having these issues at 34 and it has been very distressing as you can imagine... So I'm asking people out there how they dealt with sexual side effects on Effexor, post-effexor, or on other SSRIs if you've had experience with the Sexual side effects? Is the only option to stop Effexor to remove this side effect? -
Been on Effexor (again) 4 months. Went up to 225mg, but the lethargy and apathy was getting worse, along with excessive sweating. I'm typically someone that runs more cold (usually takes a lot for me to sweat at all!) So this is upsetting. I've started working out everyday and after the warm-up, sweat is pouring down my face & neck. Sweat towel makes no difference. I get out of class and it looks like I just stepped out of shower. At moment I'm on 112mg and this sweating persists. Would going down to 75mg be better?? Anyone recommend something with the least amount of side effects (especially no weight gain or lethargy) I'm thinking maybe just screw it, and going on something easy/basic like low-dose Prozac (also makes me sort of apathetic, guess I can't escape that) I cannot take Glycopyrrolate (anticholinergic drug that reduces saliva, sweating, etc) because it worsens my severe dry eye syndrome & blurry vision. Lamictal + Ritalin have been moderately helpful (for stabilization, slight motivation) but I need a bit more antidepressant boost to cover some intermittent labile/low moods. -
Anyone find Zoloft more motivating than Effexor? Any weight gain? (it made me insomniac with psychosis 20 years ago). But meds often act differently over time. I've already done trials (some multiple times) of: Prozac (lethargic), Celexa (fatigue/apathy), Lexapro (similar to prozac), Cymbalta (vigilance/restlessness legs, but dissociative mind/feeling), Wellbutrin (no effect), Trintillex (no effect), Remeron (sedating/+appetite), Notryptaline (don't recall), Abilify (++appetite, RLS), ..Doc won't RX MAOIs and says that TCAs typically more sedating effects. Basically, I don't want to take more than 3 meds (keeping with Lamictal & Ritalin). I want to avoid A/Ps...I like the calming feeling of Prozac & Effexor, but it's as if I am in this fuzzy cloud and I can't move or do anything, comfortably numb. Totally apathetic, in addition to sexual dysfunction, maybe my dosage is wrong. I'm also considering Viibryd, but don't know if it works on Serotonin...?
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Only Day 2 back on Effexor (I took previously for 7 months at 150mg, but don't remember much). I've literally been laying in bed, blank-minded, just staring at the wall for 3 hours. This is really not normal for me, I slept well last night (9 hours) and was up, OK & out walking earlier. I'm only on 37.5mg!...It's only Day 2! I'm shocked that I would feel effect immediately. Haven't felt this tired, heavy and zoned out for a loooong time. In fact, I don't recall feeling this numb since Citalopram or when I was on Cymbalta a decade ago. I've been consistently taking Ritalin , I had 3 coffees today....and the Effexor (obviously) has completely wiped out any stimulant effect. I mean, it's nice to not be over-emotional, stressed with crying jags, but on other hand, I don't want to be flatlined, lifeless, unable to get out of bed, no cares about anything. Please tell me this is temporary and will go away in 1-2 weeks or with a dose increase?? Does anyone know the dosage breakdown of Effexor? (for example: 37mg-75mg works on Serotonin....75mg-150mg works on Norepinephrine, etc?) I feel Serotonin overload, I thought that Effexor worked on 3 transmitters at once... I can't seem to find the right combo balance with anything (all SSRIs made me feel like this too) and many other meds are too sedating or they do nothing for me. Any thoughts? @browri @mikl_pls ?
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Quick backstory, I was on Effexor (75mg-150mg) for only 7-8 months, my pdoc tapered me off very slowly (using Prozac as a bridge) over a period of about 5 weeks. I've been completely off both meds now for 2 months. I did not have major withdrawal symptoms (except light fatigue/dizziness) and yet I am STILL getting these intermittent (mild) brain zaps sensations and brain fog - usually in the afternoons/evening. I am very worried that they will never go away... I have been taking many supplements (including Fish Oils, NAC, etc) for many months, exercising, eating healthy. How can i make them disappear for good?!
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Since I've been on Effexor for 7 months, I've had zero emotional depressive symptoms (like the crying, sadness etc) negative ruminations have lessened, no anxiety whatsoever either... Issue is, I've become more & more lethargic. I sleep a full 10 hours per night and then I cannot get out of bed. I'm not really tired, I just literally cannot get myself to do anything. I am super content just laying in bed for hours. I read crap online for hours, I often take 2 hour naps in afternoon. It pains me to take a shower & go outside. I procrastinate on work/everything... I avoid doing things I need to do just so i can lay in bed! No interest, motivation, pleasure in anything. How can I light a "fire under my ass" again? The same issue happens with other meds that work for depression, but then they cause this! And no, my doc won't increase my Ritalin (which I have a tolerance to & it stopped working). She won't put me on any other stimulants which seem to be the only thing that help me in this state. Yes, I've tried Abilify add-on...not sure if I want to keep adding more meds or if there something better I can switch out in my situation? Seems my choice is to either be emotionally depressed or a complete apathetic sloth!!! Any ideas?
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After 7 months of Effexor 150mg, my pdoc agreed to wean me off in order to see if my sex drive/sexual dysfunction resolves. I am very concerned with the withdrawals of this med. She gave me a weaning schedule, but it seems very short/quick for this drug. I am currently on 2nd day of 75mg, and feeling mainly very tired, more apathetic, lightheaded, with a bit of restless sleep. Any feedback/experiences?? Effexor 112mg (for 3 days) Effexor 75mg (for 3 days) Effexor 37.5mg (for 3 days) Prozac 20mg (for 7 days) Prozac 10mg (for 7 days) then stop....
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First off, I'm aware people here sometimes have issues when switching from Brand med to Generic. My pdoc started me on a Generic Venlafaxine, (maybe she didn't want there to be an issue at a later date, in case I wasn't given the specific Effexor name brand everytime, I guess)? I started on 37.5mg Mylan tab, and as I increased, not sure if it changed. Last 4 months, I was taking 150mg (in 1 tab pill), (can't remember the name). Anyway, I am completely confused!! I've been on different generic manufacturers and different formulations (sometimes I go to a different pharmacy, due to stock, they sometimes give me 2 75mg doses, instead of 150mg). I'm not sure even which manufacturer/brand I've been taking the longest, as I don't save the packages. However, I have noticed this last week, I've been on a different pill than months prior. I am definitely feeling different (much more tired, LAZY, spacey and sweaty) I compared my current pill (Peach, 2 dose 75mg Pfizer Venlafaxine Capsules with individual beads) to a previous one (White, Mylan Venlafaxine, it's a hard tablet inside a capsule?). I've never been on the capsule with individual beads version (usually only the hard tab). I don't know the difference between these formulations (capsule with beads versus hard tabs)!! I'm assuming there would be a huge difference in the release mechanism and absorption of the drug right? I'm not sure what to do, or which specific manufacturer/name to request now....I also read that only XR formulation exists (no instant) so all of these should be extended, right? Which ones have the best reputation?
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During misdiagnosis days, Effexor destroyed my life when I was barely 21. Severe mania, severe adhd, blackouts, being manipulated by psychopathic friends, and ruination all around. And PSSD (least of my issues then). Fixed (somehow) by 23 or so. At 29, tried lamotrigine. Further destroying my hair much like Adderall did. Tried finasteride - ruined my life (last year). Fixing now... or trying to. Literally made my face look different and caused things that look like hypogonadism. If you are healthy - stay away from such drugs especially if you already have neurodevelopmental/neuropsychiatric disorders. I'm sure a lot of pro-med people here will disagree, but I have family members who are no more intelligent than me who are married with kids, and making 800k-2million a year. The difference between us isn't that I didn't work hard nor is it a lack of ability/intelligence. It's that I spent my 20's in hell, fixed it, was lured to try another med. Though dexedrine was working -- and no doctor believes lamotrigine can cause hair loss. And trust me: Drug-caused illness is even worse. If ADHD and Bipolar (and both) have increased suicide risks, what about adding a disease that no one knows about, that doctors don't believe in (at all), that changes one's genitals, eyes, eyesight, face, and ability to function? I'm lucky in that I've seen a lot of shyt in my life and am a fighter. Others (plenty have committed suicide) would be gone. I was close at times - thanks to finasteride. I was bedridden. I won't write here again, until I'm better. By the way some of those family members I have are physicians, and trust me they don't "get PSSD", nor "PFS" (post finasteride syndrome). So if I was alone before... Well I was better off without taking lamotrigine and for sure finasteride. Fin inhibited UTG1A4 which metabolizes Lamotrigine or perhaps it was neurosteroid depletion which caused Lamo to stop working while I was on it. I have neuro, psyche, and physical symptoms (like 20) because of this. It isn't in my head. I can literally see my picture from right before I quit to quitting finasteride, my eyes look different. My vision also is different, and I think slower. I'm getting a bit better - but I need it cured asap. Fuck all this. -
I’ve been on Effexor the last 3-4 months, I haven’t felt anxious at all, or depressed. Seems great right? I increased a week ago (to 150mg), and since, It’s increasingly difficult to get out of bed in the morning. I sleep really well, I don’t feel tired. I just feel soooo comfortable, relaxed, calm, cozy and content that I just lay in bed for an extra 3 hours. My mind empty. The last few days, I’ve been completely shirking off/avoiding all responsibilities: called in sick to work twice, skipped my courses, just to lay around in my pjs and do nothing! WTF? I No desire to socialize, haven't showered the last 2 days...It reminds me when I was on Celexa - I became so lazy/apathetic/disinterested that I had to discontinue. Is there such a thing as “too much serotonin?” Maybe I should just wait things out, until I get used to it? I feel like I need to increase my stimulant & drink extra coffee just to light a fire under my @ss.
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I was taking prozac for depression, .5mg klonopin daily for GAD, and lithium orotate for suicidal thoughts. I take rozerem at night for non24 sleep phase disorder. The prozac stopped working and so my pdoc switched me to lexapro but it made me exhausted all the time- i basically would sleep, wake up, eat a little, go back to sleep... after two weeks she’s switching me over to effexor instead. I am starting at the lowest dose, but I’m not sure when to take it- is this going to be a morning pill? right now i take the lithium and rozerem at bedtime, and was taking prozac, klonopin and then the lexapro in the morning. I switched to taking the lexapro at night when i relized how exhausted it was making me. still, i slept all day and night. so effexor- i’ve read enough to know it’s an snri, and it’s a bitch to climb back off of. and it can take up to a month to work? is there anything else about this combo i should know, or does anyone have experience with these meds together? i’m diagnosed with depression with psychotic features (since the 90s), general anxiety (past five years), non24 SPD, and chronic suicidal ideation. I know the non24 is the weird one, but I’ve found ways to set up my life/work schedule to manage it- i’m not sleep deprived. any thoughts would be great, i’m a relative newcomer to being medicated- i’ve only had access to a pdoc regularly dor the last three or four years, before that it was just urgent care or ER, random doctors trying to treat me. -
I'll just preface this with info: I've tried about 30 different meds, many combos, including Cymbalta in the past (3 yrs, mixed results), It didn't greatly improve my depression, mainly made me numb, sweaty, nauseous, a bit restless/wired with sleep issues. The crazy withdrawals if I took a bit late were horrendous, so went off. Despite this, my pdoc really wants me to start Effexor (even though withdrawal is even worse). Can someone please reassure me that it worked well for you? My symptoms are: chronic, treatment-resistant depression (with some crying/mood lability), very intrusive negative ruminations, anhedonia). Is it really worth trying despite my unremarkable/mixed experience w/ Cymbalta, and fear about withdrawal syndrome? Also what were the negatives for you (i.e any weight gain, anxiety, restlessness, paranoia, insomnia?) Thanks all.
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I'm on 75mg Effexor (just under 2 weeks) and I feel incredibly spaced out. I don't feel at all depressed or any anxiety, just borderline numb and "not there." My mind is an empty void & ruminations gone, but I literally feel so detached, listless. I'm continuously zoning out during the day, and in conversation. I'm struggling to spell some words (something I'm usually very good at). I could just lay around and stare at the tv like a sloth. This is sooo not me. I've had this same effect from other antidepressants (hence why I usually end up going off them). Is this effect dose-dependent? Like, if I increase to 150mg will I feel less "tranced", more motivated or will this numbness & detachment increase even more so that I don't care about anything or anyone?? I thought the SNRI's were less likely to cause this?
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Hi, names Hibiki. Ive been struggling for 7+ years with Trichotillomania, Depression, ADD, Anxiety (agoraphobia , panic disorder, disassociation, etc), OCD (obsessive thoughts). im currently on so many meds due to my age (17) (no narcotics due to me being underage.) and my insurance being the shittiest ever. Im currently taking regularly: •Zoloft •Buspar •Effexor •Seroquel ive ran out of all options for medications so they threw me on effexor and although my anxiety has been absolutely crucial this past year and a half (3 attacks lasting 1 month +) ive noticed a strange effect pop up these last few days. So currently I feel like im here but not here. Like everything looks weird, almost like im watching life go by through a screen. Im unable to fully concentrate on anything and i just feel exhausted. I feel like im not here but i know i am. Semi like a zombie,? Its kinda like disassociating but with my eyes. Everyone i know just looks different and everything is just strange,.. i was holding my baby brother and didnt feel like i actually was? I was talking and walking and id just suddenly stop and space out. Everything just feels distant. It also comes in waves, i will feel normal for a bit and then WHAM it attacks me from around the corner just like my panic attacks. I literally cannot explain what i feel but what is this?? Anyone else kinda feel the same?? the thing is a month ago my doctor prescribed me Effexor and she told me it would take a month to get in my system, and i feel like this is a negitive effect from it. Including my memory loss . And all ive heard is negitive reviews. So im starting to panic, like horribly. Im scared im going to feel like this forever and idk what to do? Im an artist and i can no longer draw due to this and its making me worry. -
Since Trintillex had absolutely no effect (on my anhedonia), my pdoc suggested Effexor. I'm very wary about Effexor due to the horrible withdrawals I had with Cymbalta 10 years ago. I don't remember it helping me much, not worth the withdrawals. If I missed 1 dose by mistake, I would be a trembling mess with full-on brain zaps, anxiety, crying spells, the works... I have tried all of the SSRI's and most make me numb, tired & kill libido. These meds help acute depression, but what about for stable-ongoing low mood-anhedonia? Like when you feel no excitement/joy in anything? Effexor has an even shorter half-life than Cymbalta, which worries me. Question: Will Effexor help symptoms of anhedonia, low mood, low motivation? What was the main difference you felt between the two? (did they feel relatively the same, or did one work much better with less/different side effects??)
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I was wondering about this, as my PDoc didn't seem too concerned with it. I was on 300mg Effexor XR for about 5 years, over the last year I've gone from 300mg to 75mg or so mostly successfully, but lately I've been dragging along. I can easily sleep 12 hours a day, I'm still managing to get to work, but I'm exhausted beyond belief and only have windows of feelings myself. I was wondering if withdrawals to drugs like these can last for months, or even years? Especially having been on them for so long....
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I have run the gammit for SNRI/SRIs in the last 18 years. Most I cannot tolerate. A year ago I started Lamictal for treatment resistant depression. I have depression and generalized anxiety. The Lamictal initially worked great for both! However, about 6 months into it my anxiety resurfaced. The anxiety is so bad that I have trouble driving/riding on the highway because I'm afraid we're going to have a terrible accident. I am in constant fear that something bad will happen to my loved ones or my pets. I have to check everything in my home 2-3 times because I'm terrified my house will be broken into. I've started exhibiting signs of OCD. I am in therapy. Since starting the Lamictal, I've tried Lexapro (nonstop headaches for 2 weeks that I just couldn't take it anymore), Neurontin (didn't work at all), Lyrica (up to 100 mg now-takes the edge off but not completely), Seroquel (made me so angry-like a total personality change and felt pressure in my chest) and propranolol (did nothing). My neurologist had suggested going back on Effexor for my migraine headaches. I took it for 9 months but it seemed to exacerbate my anxiety. I'm currently on 200 mg of Lamictal. I am super frustrated! I feel like my pshychiatrist is throwing meds at me & she's more or less told me we don't have a lot of options left and talked about compounds of Klonipin or herbal remedies. I guess my question is: should I start over from scratch? I've read others comments that said Lamictal caused them to have anxiety. Lamictal works for my depression but my anxiety tends to depress me because it just wears me out and I feel at the end of my rope! Or is there something else I can add? Ive tried: Zoloft, Paxil, Wellbutrin, Cymbalta, Lyrica, Neurontin, Seroquel, Propanolol, Lexapro, Effexor Please give me your thoughts! -
I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream? -
I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream?
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I'm 40 now. One time I was 22 and knew I needed help so I went to a therapist and she gave me herbal pills and acupuncture. Me, I still wanted to die and I knew there was SOMETHING out there but alas, moms insurance. Needless to say I became more depressed and sat in the cellar of a goth club staring at the wall for 5 years. Numb n drunk. Poverty did not enable me to seek meds but there was a clinical trial for Viibryd in 2012 which I did for three months along with Trazadone. It helped me get out of a dead end life im Seattle with a BPD type (you know how us codependants roll) and move to California. Must've not been a placebo since the withdrawal cold turkey was a week. Fast forward to Obamacare and asked for Citalopram. Big mistake. Called in sick to work,sweating like a crackhead and bipolar like behavior. Tried Buproprion. No side effects but didn't really *do* anything. Sooo....Cymbalta for 5 weeks and I just get more exhausted every second, take two naps a day on top of 8 hours of sleep. I dont have the fibro but do have back pain (DDD) I stuck with it, wouldn't you say? I even doubled the dosage to 120 which made sleepy times worse. I didn't suffer any side effects except the sleepy part. So go to shrink and he immediately wants to start me on generic Venalaxifine 35. whatever to 75 in two days. I asked about stimulants like Vyvanse or Adderall but he refused, though he was just fine prescribing Xanax and this Lorazapam. SO: Anyone had any luck doing this crossover. If it gives me at least more of a boost than Cymbalta, which just made me want to buy flowers and eat ice cream and pass out every three minutes, I would love to hear your experiences. Sorry so long, am newbie, and lonely in this waking dream?
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I took Effexor for one day and experienced horrible side effects - vomiting, sweating, nausea, shaking, sleepiness. That was three days ago, but since then I've been sleeping all the time and am still shaky. Has anyone else experienced something like this after only one dose? -
Has anyone been on Pristiq and Seroquel at the same time? Or Effexor and Seroquel? I was just prescribed Seroquel (25mg morn + 25mg noon + 100mg night) after being on Pristiq (100mg daily) for three months with little improvement in refractory depression. I am nervous about starting Seroquel. I want to have hope but *sigh* after all the meds I've tried I kind of gave up on that.
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Has anyone ever had any experience with this mixture? I can find info about any two of those mixed together but not all three.... Any suggestions on something that might work to combine the depression and anxiety into one that mixes with Adderall well? -
Starting Effexor XR
MarchMayhem posted a topic in Antidepressants - If You're Crappy and You Know It
Hey there, new user here. My doctor started me on Effexor XR, 37.5mg once a day. I took my first dose today around 5, after a couple days reading up on it. I don't know if my mind is just making it seem like I'm having side effects already or what, so I was just curious if anyone experienced the side effects a couple hours after taking it as well. I feel like I'm already getting sweaty, and my vision seems to be getting blurry as well. My heart also won't stop pounding but that could just be because I'm worried about starting the medication. Any feed back would be nice, as well as your personal experiences with it over all. The doctor also prescribed me propanalol to take as needed when I feel anxious and I haven't seen many stories of experiences with it for anxiety, so thoughts on that would be nice as well. Thank youuuu -
Hi there, new to this place, wanted to know if anyone had any issue adding Adderall to their pre-existing Effexor script. I'm on 225 of Effexor XR, and since adding Adderall (it seems) but I'm not sure- that I'm withdrawing from the Effexor. I know this makes no sense... Symptoms- feeling brain zaps, eye shutters, which increase as the evening and night sets in, feels EXACTLY like Effexor withdrawal to me, and I've come off it about 3 times in the past ten+ years so I know thats the familiar feeling. However- I'm sooo confused b/c my dose has NOT changed. And the only real difference is the Adderall, which I take 25-30 IR everyday. Please help- I am realllly uncomfortable with these feelings as its like everyday I withdraw or something. I will not forego the Adderall though.. Should I try another SSRI? I have pretty bad depression, and anxiety (which the adderall helps strangely enough), a bit of OCD (thoughts only), and Innatentive ADD. Also, I've been on the effexor-adderall for about 1.5 months and this has continued and seems to be getting maybe worse- slightly. It started about 2 weeks in. THANK YOU!
