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I am taking stimulants for numerous reasons--primarily for ADHD and idiopathic hypersomnia, but also because I'm obese and trying to lose weight (with diet and exercise of course) and because amphetamines heretofore have been the only thing that really make me a functioning human being. I was curious though. From y'all's experience, which stimulant inhibited appetite and/or caused more weight loss, that is, between Ritalin (and all their products), Focalin, Adderall, Dexedrine, or some other stimulant. I have actually even taken Desoxyn, twice, and to be honest, it's nowhere near as potent as Adderall or Dexedrine. To my understanding, appetite inhibition can be extricable from weight loss; i.e., one can lose weight from a medicine without experiencing much appetite suppression, one can experience drug-induced anorexia without losing much weight, or both at the same time, or neither. IME, so far, this is what I've experienced... I'll list the stimulant/anorectic and max dose taken. Appetite suppression/anorexia: Dexedrine (60 mg) Adderall (60 mg) Dexedrine Spansules (30 mg) Adipex-P (37.5 mg) Adderall XR (90 mg) Wellbutrin IR/SR/XL (450-500 mg) Bontril-PDM (210 mg) Tenuate (75 mg) Desoxyn (15 mg) Vyvanse (70 mg) Adzenys XR-ODT Metadate CD (20 mg) Ritalin (30 mg) Focalin XR (25 mg) Evekeo (20 mg) Belviq XR (20 mg) Tenuate Dospan (75 mg) Contrave (32 mg/360 mg) Weight loss: Dexedrine (60 mg) Adderall (60 mg) Adipex-P (37.5 mg) Tenuate (75 mg) Dexedrine Spansules (30 mg), Adderall XR (90 mg) Wellbutrin IR/SR/XL Desoxyn (15 mg) Bontril-PDM (210 mg) Metadate CD (20 mg) Belviq XR (20 mg), Evekeo (20 mg), Focalin XR (25 mg), Ritalin (30 mg), Vyvanse (70 mg) Contrave (32 mg/360 mg), Tenuate Dospan (75 mg), Adzenys XR-ODT So I've not tried very high doses of the (dex)methylphenidate meds, and have been curious about trying a higher dose (40-60 mg, maybe higher). Focalin might be okay, but it gave me tremors, anxiety, and panic attacks at 25 mg. Vyvanse did nothing much at all except jack my resting heart rate up to 120+ BPM. This list was very hard to compile, and I don't really know if it's too accurate. I'm heavily considering trying methylphenidate again, specifically Metadate CD, because I actually felt something on it as opposed to regular Ritalin. I was considering asking my NP for a Metadate CD dose of 30-60 mg, or maybe 30 mg x2 or something like that, with some Ritalin 5-10 mg, maybe 20 mg, to take 1/2-1 up to three times per day prn. The tried and true med is Dexedrine for me, specifically the IR, but I want to give that a break for a little while. I'm curious to see how (dex)methylphenidate affects my ADHD more than it affects my weight loss/appetite suppression as well. I know this post was rather scattered and long, but if you made it through it, any input would be much appreciated!

I'm currently taking Vyvanse, and I've heard that straight amphetamine-based stimulants like Adderall and Vyvanse can be stronger stimulants than the methylphenidate class like Ritalin, Concerta (Ritalin XR), and Focalin. I'm considering talking to my doctor about something more mild, and I'm looking at the methylphenidates as an option. What I know about Adderall and Vyvanse is that there are differences. Even if Vyvanse is just the dextro- enantiomer of the amphetamine molecule. What I also know is that dextroamphetamine (along with lisdexamfetamine) has more of an effect on dopamine than levoamphetamine which is found mixed with dextroamphetamine in Adderall, and levoamphetamine has more of an effect on norepinephrine. Are there similar differences between methylphenidate and dexmethylphenidate? Where one may effect a certain neurotransmitter more than the other would? I'm curious specifically about pharmacology differences and even the slightest differences in mechanism of action. Curious as to what anyone might have to say here.

I was diagnosed with ADHD when I was 12, put on concerta. I wasn't really fidgedy, I just started puberty very early and around that time I started being bored with everything and not being focused. I've been on and off concerta, focalin, and focalin xr for years, but after a year of not being able to be prescribed scheduled substances, I got put back on focalin in June. I just have an addictive tendency and always go overboard with it, considering I've been dealing with a meth addiction. Does anyone have any tips on how I can control myself, or tell myself when to call it quits?