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When i was first diagnosed 2007, the meds turned my life around with a week. Mostly because the Lunesta gave me a full night's rest for the first time in years and i finally gained some sanity. (Now I'm on Ambien, not Lunesta) Now, my GP is telling me that even though i'm depressed most of the time, the meds are at full capacity. This is as good as it gets. He wants me to get into cognitive therapy, but i"ve gone that route with limited success. He increased my Seroquel but that triggered so much dizziness that i ended up in the ER. Back down to 400mg Seroquel. I had a major set-back in early 2013. Went catatonic and was hospitalized for 3 weeks. No hospitalizations since that time, but I'm always worried that i could end up in the hospital again. I have never gone off meds even when i felt better. I have accepted that I have this disorder and will be on medication for life. So what does one do when you felt like normal, functional person but slowly digressed into a dark place? I am so tired of battling this. I have days where the depression is lifted, but it always returns. And I'm so tired of not knowing from one day to the next how I will be. My life is really crappy right now.