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Found 24 results

  1. Hello People So I'm in the process of tapering off mirtazapine (Remeron) and seem to be having some pretty shitty withdrawal effects. Some are physical (teeth grinding, fatigue), but some are returning/worsening mental health symptoms (shitty mood and emotion regulation, increased depression, anxiety, indecisiveness, and obsession). The goal in tapering off this med is to eliminate it's "hangover effect," so I'm hoping this is just some extended rebound effect/temporary withdrawal symptoms. I can't seem to get out of bed in morning and make it to work on time to save my fucking life in any case, so it would be nice if I could eliminate one factor in that. It's been 2 1/2 weeks since I went down 3.75 measly milligrams, but I don't know if I can take much more of this. Any experience with this? Suggestions? Oh, and when I called my psychiatrist, a nurse called me back and said withdrawal effects should only be physical...bullshit, right?
  2. Hello everyone, my name is Nicholas and I'm a 21 years old guy from Italy. I suffered from chronic insomnia from the age of 15 and in mid-February 2017 was prescribed before bedtime the antidepressant mirtazapine at 15 mg and the antipsychotic olanzapine at 2,5 mg. I took them for 2 weeks without improvement. Therefore the psychiatrist increased mirtazapine at 30 mg and olanzapine at 10 mg. Now I believe that he thought I had bipolar disorder type 1 but I hadn’t any mental illnes. I took olanzapine at 10 mg because I think was only a tranquilizer and because I trusted the doctor. Olanzapine made me sleep for 13 hours but I was no longer myself. After 5 days I tried to split the tablet but it gave me a strange effect. So I continued for others 15 days at 10 mg because I really needed to sleep. Then in April 2017 I tapered olanzapine in 1 week because I could not live anymore like that. I took it for a total of 48 days. After this I reduced mirtazapine to 15 mg and 1 week later I stop cold turkey. At that time I took the benzodiazepine brotizolam at 0,25 mg for 2 weeks to help me sleep. The withdrawal symptoms were terrible for 4 months and I have not been the same anymore. When I was on mirtazapine and olanzapine I had eyelids fasciculation 2 or 3 times per day. When I quitted olanzapine the eyelids fasciculation ceased. 2 weeks after withdrawal from olanzapine and 1 week from mirtazapine I started to have frequently intermittent muscle twitching in the left thigh and occasionaly pulsating muscles in other parts of the body. After less than a couple of months they have decreased in frequency and intensity but didn’t stop completely. During this period I was forced to take the antidepressant sertraline and the benzodiazepine diazepam because for the new psychiatrist I had obsessive compulsive disorder with an obsession for the damage of antipsychotics. I did not have anything like that and could taper and withdraw after 3 months in July 2017. Now I think maybe that the muscles twitching have diminished because diazepam is also a muscle relaxant. In August 2017 I started to have continuous fasciculations in the legs when I lie down and less frequently when I sit while I never had them when I move. Few times a day I had pulsating muscles also in the arms and the trunc but never in the face. I never had muscle twitches in multiple parts of the body at the same time. In September the muscles twitching moved for 1 week in the lower abdominals. In October 2017 for 2 weeks the muscles twitches suddenly stopped in the legs and continued in the rest of the body about 10 times per day. When the muscles twitching returned they were milder. Sometimes the fasciculations are so mild that when I looked at my calf I saw them without feel them. In the legs they have become more single rapid muscular contractions than pulsating muscles. Soon after I started to have continuos pulsating muscle in my upper lip. The muscle twitch was very mild and lasted 2 weeks but after it I have sometimes pulsating muscle also in my face. Do you think it is a tardive dyskinesia caused by olanzapine despite I haven’t involuntary body movements? Do you think it could be some other side effect caused by olanzapine or maybe mirtazapine? It’s 8 months that I’ve it. I have been visited by several psychiatrists and neurologists and everyone said it was just stress. Even if I do not have the symptoms of tardive dyskinesia I do not know what else it could be: I’m not stressed and I do not suffer from anxiety, I do not take stimulants, I can sleep, I have had blood tests and I haven’t electrolyte imbalances or hypoglycemia, I did electromyography and had normal results. The thing that worries me most is that there is a very large amount of medical literature that associates tardive dyskinesia with cognitive impairments. If it were to be tardive dyskinesia do you think that the fact that for almost 2 weeks the muscles twitches had almost disappeared means that I am healing? Thank you and greetings from Italy.
  3. Hi, I have been on Remeron for about three years for anxiety, OCD, and depression. I started at 60mg, but that was pretty stimulating after dosing it all at night. Now, I take 22.5mg before sleep. Depending on my legs/hips tension levels, I always get restless legs about 45-60 minutes after my dose, and it keeps me from sleeping right away. I've had this since I started the med, and now that I do yoga/stretching, it's even been worse. Some nights it is very severe. Would lowering to 15mg help? Or anything else? I wonder if it's a histamine or noradrenaline thing. Thanks.
  4. I'm having a hell of a hard time and experiencing rather weird symptoms. Whether they've anything to do with Mirtazapine (Remeron) is something that I strongly feel but can't quite convince any doctor of. I was put on 15 mg of it in spring 2015 for depression and a severe insomnia - I hadn't slept an hour like since 25 nights back then! The benefits showed immediately within a day and surprised myself and my family. I would sleep well and be in a very happy and cheerful mood. Then however, from summer 2016 I developed some strange food intolerances; caffeine, sugar, fruits containing high amounts of fructose, yoghurt, butter and so on. Eating anything of that would cause me jitteriness and insomnia. I steered clear of those foods. From autumn last year though, a lot of those food intolerances have relented and it changed into intolerance towards medicines and supplements that I was on; the thyroid medicine for hypothyroidism, Vitamin D, Calcium, Vitamin E and could never again tolerate any new medicine or supplement. Symptoms resulting from these are, again, jitters, insomnia and a strange kind of feeling of being struck on the head, like I can't hear anything and the thinking becomes very unclear and blurred. Coupled with this is a weird sensation that if a medicine has any potential side-effect (even physical, such as urine retention), I get it at all costs. So I'm steering clear of the culprits here too. However, avoiding the culprits doesn't end my misery, it just helps in avoiding a whole new set of symptoms, because since autumn 2016 I'm under constant brainfog anyway, have heart palpitations immediately after every meal (but worst after breakfast), have concentration and focus issues, lead a life without any hobbies, wishes or desires. Nothing excites me, nothing interests me and nothing catches my attention. Leave tasks pending for months (the most unlike me habbit), have badly lost my sense of humour. My sense of humour was something that I literally used to pride on, and friends from around the world would call me to fresh up if they were having a dull day. My mind feels numb, although it isn´t as if it´s the sedating effect of the Mirtazapine because 90% percent of the nights I don´t sleep well, and on a lot of nights I feel as if I´m asleep with an awake mind! Amidst all this, although initially not effected for the first 17 months, but the libido is not non-existent. If I get them at all, my erections are very tiny and hardly last a minute. The GP who put me on it considered it to be just the effects of anxiety and depression and recommended the doubling of the dose to 30 mg. When I contested that, given that I´ve my doubts of a lot of these issues being brought upon by Mirtazapine itself, she referred me to a psychiatrist. He too strongly denies of Mirtazapine having any hand to play on it and instead thinks it´ll be best to combine it with another antidepressant for day-time. He put me on Paroxetine, boom, a flood of side-effects! Then changed to Fluoxetine (Prozac) - third day on it and having weird feelings. The heart poundings are one and is in fact making me very depressed and hopeless!
  5. I am on two antidepressants, and lorazepam prn (1 to 3mg) I still am nervous in a few social settings, especially if I am put on the spot, or if I feel put on the spot- not hard to do to me really. I get social anxiety which is quelled by lorazepam. I have a panic disorder that is now somewhat controlled, but I take lorazepam for certain situations (haircuts- I've had a panic attack during a haircut). I have essential tremor, of the upper body. I sleep better, and cry an awful lot less now that I take antidepressant medication. I find taking the lorazepam calms me when needed but can create mood swings when I take it sporadically. It's like my depression and anxiety rebounds after it clears my system. I feel okay, but not totally okay. Can I fix that, or is this as good as it gets?
  6. Hi I have just joined here out of desperation. It's a long story but feeling as if I can't carry on at the moment. I had severe post natal anxiety, insomnia and depression 10 days after giving birth 4 years ago. was put on mirtazapine 45mg which got me back to myself for a year. I tried to go on contraceptive pills microgynon and loestrin both of which sent me spiralling back into the worst depression. Stopped these and couldn't really get over the hormone problems so added venlafaxine 37.5mg to mirtazapine which worked great for a year. Since December 2015 I have had to increase my venlafaxine 5 times so now I'm on the top dosage of both venlafaxine and mirtazapine. My relapses always happen 10 days before my period and I get so bad I can't even function and have suicidal thoughts so I have to increase my tablets. I am 4 days in to my last increase and 5 days before my period and I just can't cope. My doctor has given me a prescription for a progesterone only mini pill, he has said to take this after my period so middle of next month when I'm feeling better but I am PETRIFIED that it will make me even worse and I can't increase my anti depressants. I honestly feel if this gets any worse I will have to hospitalise myself as I am so tired of fighting this awful thing and it never gets better. I have cervical erosion since the birth of my daughter and had this frozen two months ago and since this my last two periods have been hell and I feel as if I'm having a breakdown. My GP says this procedure wouldn't have affected my hormone levels. I also take supplements Agnus castus, vitamin B6, magnesium, calcium, vitamin d, evening primrose oil, vitamin b complex food supplement and exercise when I am feeling well. I just don't know what to do anymore should I take this contraceptive pill? If anyone has any experience or advice please please contact me I am desperate. Thank you
  7. For years I've been taking remeron at night for sleep and it helps a lot with my appetite. Last week my doctor switched me from remeron 22.5 mg at night to hydroxyzine 50 mg before bed. He said it would be kind of like getting the antihistamine benefits (sleep, appetite) without the noradrenic and serotonin action of the remeron (remeron tends to make be too activating for me, increasing my anxiety). Does this sound about right? I started the switch 2 nights ago and felt alright until just a few hours ago when I started getting really paranoid and feeling like I was panicking and just out of it. My appetite has been good though, I get real hungry about an hour or so after taking the hydroxyzine just like I did with remeron which for me is a bonus. I'm wondering if my dose at 50 mg is too high though. I'm also taking valium 5 mg twice a day and effexor 37.5 mg once a day.
  8. Whenever I've been on remeron, or anything that has strong antihistamine activity, I notice a lot of physical changes. Well the good thing is that it really helps with the physical symptoms of my anxiety, my body which is normally very stiff and tight all over feels more relaxed and loose. But at the same time whenever I stretch real good I get the most agonizing pain in my tendons wherever I stretch. Also my joints hurt a lot in my fingers and toes and I get plantar fasciitis often. Is there any correlation between connective tissue and use of antihistamines or remeron in general?
  9. Whenever I've been on remeron, or anything that has strong antihistamine activity, I notice a lot of physical changes. Well the good thing is that it really helps with the physical symptoms of my anxiety, my body which is normally very stiff and tight all over feels more relaxed and loose. But at the same time whenever I stretch real good I get the most agonizing pain in my tendons wherever I stretch. Also my joints hurt a lot in my fingers and toes and I get plantar fasciitis often. Is there any correlation between connective tissue and use of antihistamines or remeron in general?
  10. Hi all— I started taking clonazepam for sleep and anxiety on Thursday evening. Today is Sunday. My current dosage is 1mg at bedtime. I am also on mirtazapine, 30mg at bedtime, for depression. On Friday I woke up feeling refreshed, as though I was alive again, after a full night of sleep. That same day I noticed what looked like a bug bug bite on my right cheek which I dismissed as such. On Saturday I had another bug bite under my right eye, again I brushed it off as a bug bite. But today I woke up with the same bites, this time a lot more red, tender, and itchy than the previous days. The right side of my face shows a clear rash starting over my eyebrow through the right side of my nose and finally descending to my right cheek with a splotch under my right eye. I don't feel any worse, nor have I had any changes in vision or anything else that warrants immediate attention. I've notified my doctor and I will be hearing back from him on Monday. Should I be worried? Has anyone else had a similar experience? I don't want to stop taking it because I don't want to stop sleeping again. I wonder if the rash will disappear as my body gets used to the medication. Any feedback is appreciated!
  11. This is my second post. So again, bear with me. I have some issues with substance abuse, depression, and just about every type of anxiety disorder you can find in the DSMs. With my "addictive personality," Adderall has become a drug that I just can't get enough of. I've been taking it for over a year and have come to a conclusion that if I keep taking it, things will only get worse than they are now. I don't have a job and live with my parents. I'm a part-time student and only take a couple courses per semester. It's been years since I held an official job. At first, I thought that Adderall was enhancing my performance--in everything, but that couldn't be further from the truth. The most I've gotten out of it are As in my classes and repetitive artwork that seems to be getting "bland" over time. After a ton of obsessive research, I concluded that mirtazapine might be the key to curing my anxiety and depression, help me gain weight, and quit Adderall. I don't want to get into pharmacology of the combination of Adderall and mirtazapine, because I'm way, way too tired. Anyway, my doctor agreed with me that mirtazapine may be a fantastic option to cure all of what I've stated above. I was prescribed 15 milligrams to take nightly. The first night I was out cold, and the next day wasn't too bad at all. The second day (today) however, I'm cranky, impatient, exhausted, and guilty for not doing anything with my life. I know I want to give this medication a fair shot, but I'm one of those people that read up way too much on other's experiences with medication. The positives so far are that I'm not craving Adderall as much as I usually do, and clonazepam (which I forgot to note) isn't really needed either. Still, with this lethargy there is absolutely no way I could hold a job or even continue in school. All in all, I want to know if anyone can relate, especially if they have been on Adderall and mirtazapine simultaneously. Also, has anyone quit Adderall cold-turkey from a 40mg dose (or over)? If so, how long did it take to get your mental and physical energy back. I have the rest of summer to solve this, but as all people that take pharmacueticals know, seeing a doctor/psychiatrist every two weeks and continued trial-and-error fails takes so much time, money and stress. Thanks.
  12. I got my refill of my mirtazapine 45 mg the other day and my pharmacy had switched to the generic made by apotex which I had never tried before. It is in the manufacturers bottle, and when I open it it smells like really strong chemicals, kind of like paint or something. I know sometimes meds can have a unique smell but this is really potent, and of all the meds I've been on all these years, including all the other makers of mirtazapine, I've never smelled anything like this before. I also don't seem to be responding to the apotex brand, as I've woken up at least once each night which has never happened with any other makers of mirtazapine. My appetite isn't as strong either. Should I be concerned about the toxic smell?
  13. I've been taking Adderall IR for a little while now (few months) taking 30mg at 8am and another 15mg at noon, and recently just added Remeron 15mg every night for sleep. I've been noticing a major fluctuation in my moods about 1-2 hours after taking the Remeron. So in addition to the somewhat slumped feeling I had already from the daytime meds wearing off, once the night med kicks in I am just like totally depressed and out of it. Has anyone else tried this combination and what effects did you see occur?
  14. I was wondering if anyone could give me some advice. Basically, I'm prescribed Mirtazapine 15mg, and due to a mix-up, I can't get my prescription filled until a few days after my current one runs out. So I've got 3 pills left, but its 6 days until I get the next lot. I've accidentally missed one day before, and it's been pretty bad- I have no idea how missing more than one day in a row would affect me, and I can't afford to have to miss university or work. Does anyone have any advice on what would be the best approach out of : A) taking 1 each for the next 3 days, then going without for 3 days. B) taking half of one each day (a problem with this approach is that the resulting 7.5mg dose isn't regarded as having an antidepressant effect). C) taking one every other day.
  15. Hello. I started taking Mirtazapine at 15 mg two weeks ago and was tapered off of Zyprexa from 5 mg to 2.5 mg. Starting this Sunday, I have been having strange thoughts about harming others to the point of obsession. I've had OCD in the past, but I've never had these type of thoughts before. I've gotten totally off of Zyprexa before so I don't believe it was due to Zyprexa withdrawal. Could it be due to the Remeron?
  16. This is my second post since joining. I am looking to find out any info about what my combination of meds is doing inside my brain. Look at my introduction post if you want to know about my condition. I am now prescribed venlafaxine 150mg in the morning, mirtazapine 30mg and quetiapine fumarate 150mg at night, with clonazapam 2mg PRN. I know how the venlafaxine and mirtazapine theoretically work together to boost 5ht and NE "California Rocket Fuel". I know that since i'm only at 150mg Venlafaxine it is only acting as a SSRI, but i think i probably will have to increase to 225mg soon, changing it to SNRI. My question is what is the quetiapine fumarate 150mg going to do? What are its affects going to be upon 5HT NE DA systems as an adjunct to the "California Rocket Fuel"
  17. I am on 30mg now, and supposed to go up to 45. Pdoc says I will probably need a high dose to combat the OCD anxiety. He says he usually doesn't like to go above 60 mg with this med, but has a few patients on as much as 90 mg. Anyone taken this med at high doses? Was it successful? Seems like a lot of people are on this as an add-on, or for sleep/appetite at lower doses.
  18. This is really embarrassing, but I have had breast soreness since I started mirtazapine about 6 weeks or so ago, and it has not gone away. It started in both breasts, and now it's just on one. I asked my psych about it, and he said the med shouldn't do that, but I wanted to see if this had happened to anyone else. It seems like too much of a coincidence that it started right when I started the med. I am not pregnant or on any hormonal birth control methods.
  19. I have noticed since starting this med, typing or texting is more difficult. I am constantly hitting the wrong keys/buttons. I have never been a great typist, but this is ridiculous. It's a pretty minor complaint, but it sure is annoying. I have to correct everything I type several times more than I normally would. Finding words is harder too, sometimes. Is this normal?
  20. Went for my usual psych appointment yesterday and pending blood tests back (which haven't been taken as I have to wait till NEXT Friday to have them done) they have decided to add in a 'new' AD called Valdoxan. I currently have SAD, GAD, and suffer from anxiety attacks which can be brought on by the constant worry I seem to be under. Has anyone else taken this with Mirtazapine, if so, did it help at all? Currently on 45mg Mirtaz which I take in the morning as I find it has no effects on sleep (same with Zopiclone). My current meds are in my sig, and I'm just asking for any thoughts or comments on this combo Thanks and current thoughts on Valdoxan are more than welcome.
  21. So my pdoc put me on mirtazapine to treat a combo of anxiety (mostly) and depression (moderately). 15 mg. It doesn't really sedate me at all which is a good thing i suppose. No, i do not have insomnia. Is there still a chance it will work or is my body not absorbing it. Like everyone, it makes me really hungry. I hoping after a couple weeks it reduces agitation.
  22. So my pdoc, well she, has me on 100 mg of Lamotrigine. Then, added 15 mg of mirtazapine. The lamotrigine was for treatment resistant depression, the mirtazapine got added to help top that and to help with anxiety/obsessive thinking. Anyway, after adding mirtazapine a week ago, i feel very satisfied. I have this nice satisfied, calm feeling and feel good. No, it does not sedate me for some oddball reason. With the increased appetite, however, i am eating healthy. There is something unique about mirtazapine that recaptures the initial magic i experienced on the ssrisOh and p.s. is it safe liver-wise to take two medications. i cant help but wonder if we are damaging our livers taking a cocktail
  23. So i am going to try and convice my pdoc to prescribe me mirtazapine for residual anxiety. My concern is that it is supposed to enhance norepinephrine and increases frontal lobe activity. this would be bad for generalized anxiety, no?
  24. I am curious about using remeron for refractory anxiety. The problem is that i'm not sure if it really does reduce anxiety or if it just makes you so so sedated that its hard to feel anxious. see ssris pooped out for me a long time ago. i feel like i still need to tweak my serotonin system and i like how remeron is "supposedly" a 5ht2 antagonist. anyway it sounds like for most of the negative reviews no one stuck on it long enough just because they hated sedation
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