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Showing results for tags 'mood-stabilizers'.
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I've been on and off antipsychotics sporadically for the last 7 years since age 22 (since 2011). I'm extremely sensitive to them and have a very high response to every one I've been on. I've gained 145lbs from an increase in appetite and metabolic changes, have severe akathisia that is utterly insane and makes me want to cut my own legs off, I developed severe gynecomastia from Risperdal and Invega respectively (Won the Risperdal lawsuit, but no surgeon will touch me because of my weight), experience anxiety (The most on Abilify), fatigue, drowsiness, impotence (On Fanapt), anhedonia (From aggravated depression on Haldol), blurred vision (On Fanapt), lack of concentration, mild tardive dyskenesia (In combination with TMJ syndrome, I think it's permanent), dry eyes (Can't secrete my own tears), nasal congestion (aggravated, because I have it anyway without taking APs) , disorganized speech (Literally developed a speech impediment from a combination of Fanapt and Topamax), GI issues, etc I've experienced almost every common recorded side effect from this category / class of drugs. The lack of control over my weight and appearance and the akathisia are the worst (that's why they're listed first and reiterated). These drugs have destroyed the relatively abysmal life I had before I developed this illness and presently cut it down to absolutely nothing. I have no life. I spend the majority of my life either going to multiple doctor's appointments for my medical issues or otherwise eating uncontrollably, and pacing back and forth and smoking cigarettes occasionally. I browse the internet with my thoughts racing. I might try to watch a TV show or play video games or play bass guitar like I used to but I can barely hold concentration or focus long enough. I want this to end, I really want out. I want to experience a fraction of life again. I was previously diagnosed Bipolar 1 With Psychotic Features before my 2nd and most recent episode. As I said, I haven't taken APs consistently for 7 years. I've gone off of them twice for pretty significant periods of time before I relapsed. I usually last about 10 or 11 months (almost a year) without symptoms and perform consistently better in life in general with everything gradually going back in my life to when before I was 22. The side effects and depression usually disappear within a week. At 5 to 8 months I'm very stable, but in just under 11 months I start feeling like I'm on top of the world, become severely manic and delusional, hallucinate, experience an episode, and get into legal trouble. The 1st time around, I resisted arrest during a welfare check called in by my parents and went to the hospital and the 2nd time I successfully eluded the cops by motor vehicle on the highway and got caught hours later and went to county jail. I understand I could be facing harsh consequences but I've never been on a heavy mood-stabilizer before. All they do is overload me with APs. After the 1st episode I stopped taking psych meds completely because of how much I despised how I felt except for Zoloft and resisted almost all treatment. I avoid SSRIs now and will this time because I think it may have been responsible for raising my mood too much before the 2nd incident took place. The key to preventing future incidents for me, I believe, is to make the hallucinations and mania more tolerable to where I won't feel the need to act on them. The delusions are a joke, I can easily handle them. I'm currently taking Latuda 20mg and I'm requesting that my psychiatrist allow me to keep 2 or 3 bottles stored in my cabinet or 1 on me at all times in case any symptoms were to occur while taking Lithium. During the last episode, I was frantically searching for antipsychotics or any appropriate psych medication but didn't have them because I threw all of my former meds away after the first episode had taken place. This time I will have them to back me up and if it turns out that I need to suffer immeasurably on Latuda 20mg or another AP for the remainder of my life then so be it but I deserve a chance on a mood stabilizer simply because of what I've gone through and what I'm experiencing on APs. Has anyone ever tried Lithium as monotherapy for schizoaffective disorder or bipolar 1 with psychotic features? I hear it still has some side effects (would like to know what all of those are) but that it's immeasurably more tolerable than antipsychotics. I realize many people use it in combination with an antipsychotic but this is not in reference to that. Is there anything better than those two that's not an AP? This post is simply to inquire about anyone's thoughts or experiences about using Lithium or Lamictal as monotherapy for schizoaffective mania. A dosage and frequency recommendation would also be appreciated from those that have taken it, although I realize that I will ultimately need my psychiatrist to determine that. I found 1 study on this subject from the early to mid 1980's here: https://watermark.silverchair.com/10-1-30.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAcYwggHCBgkqhkiG9w0BBwagggGzMIIBrwIBADCCAagGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMAypxqSBIPHx7kbXfAgEQgIIBeTskilYIIUxtfy4i-FH7a6BQ4SrsYxqZG44q7kWx1rVJdLbZ4PMxE33_FUje8rDj4FoUYJI27hYGzv-06pCL6xPDrbVg7n-g9QzqTwoPiRxgDv2VnqzwifudoudTuskAGEKItv5TfD1_V9opXCFF7vJXJln8ij8NeNkMLUpe_n-Xbp6TtkU7rXYdPCZ9dObhTfmQ4PEHkwKfcJcOVAjXzelMWD1EPzWPxCK5zu1l1d2w8ojnqH68mbvgaDuvBxyPTY-EEdADh9N0NIUPQCWHXZKWE2gEBsG_AbWS-bkPdgjxtXcn8Y_5KljQbU2Geb_ERYYWuWFMEk6CRs7FYte_16TOiCQVlahMabKxw0BdjlqvdGaPYZTKBoBWb9Poswigg8jbF1whmlo7WWRyCLCLdbKt4xkmZCU0qmv_j5FTFzeXsq05ptOFY10M3jpUft1xV75pMsPtVJ8U7d42OYqMksXhZyrA8B5k9XNhfJGS0XgmTTSLHNOdcTY2
I've had two previous major psychotic episodes while off my medication for long periods. These episodes put me into a manic frenzy that caused legal problems. Once where I isolated and resisted arrest on foot and the other where I resisted / eluded by motor vehicle across 3 counties. One occurred during a heat wave in mid-July and the next during frigid temperatures in mid-January, thus extreme temperatures are one of my triggers. Thankfully there was little damage and no one was hurt either time. My lifestyle pattern involves me taking anti-psychotic medication by court order (usually by injection) for 1 to 2 years for probation before going off and feeling consistently better from the lack of adverse side effects (akathisia, drowsiness, suicide ideation, anxiety, panic attacks, anhedonia, hopelessness, severe weight gain, etc). I do well for about 7 to 8 months but then begin to isolate in my apartment and decompensate and become delusional and manic, thinking I possess special abilities and evolutionary traits and can communicate with a higher power. There is some paranoia involved as well. Sometimes I hallucinate. Then I relapse and become frenetic. There is however, little to no depression when I'm off the anti-psychotics. When I take them I'm severely depressed. I have seen a number of psychiatrists since I developed this illness in 2011 at age 22 and been labeled Paranoid Schizophrenic, Schizoaffective, and Bipolar 1 With Mania. None of them are completely synonymous and my current psych can't make up his mind. I'm very sensitive to anti-psychotics. Only 1.25mg of Zyprexa zapped my delusional thinking and hallucinations in a few hours and Invega Sustenna 39mg (what I'm currently taking) is more than enough for treating my symptoms as well. The same thing with 2mg of Abilify. I'm just saying this because I've heard that some individuals need moderate to higher dosages for the medications to be effective. I'm not one of them. Anyway, I came across one psychiatrist who was part of the justice system (in the beginning of my term) who refused to place me on an anti-psychotic claiming I was too focused during my occurrences with the police for him to diagnose me Schizoaffective. He said that I still retained some sanity based on what he was told and wasn't trying to murder anyone or hurt myself. He refuted Schizoaffective Disorder and labeled me Bipolar 1 With Mania And Temporary Psychosis and said I had one of the most extreme cases of Mania he had ever seen. He recommended a heavy mood-stabilizer instead of an anti-psychotic. He said there may be some delusional thinking but I will remain baseline and wont act upon them. Unfortunately, I was extradited within a few weeks and placed out of his care and the next psych I came across was an AP dispenser and convinced me to take it so probation would accept me. The only mood-stabilizer I've tried is Nuerontin or Gabapentin and I wasn't on it long enough to know if it treated my symptoms effectively. I come off probation in December and don't want to get in trouble with the law once again, but at the same time I despise what these anti-psychotics are currently doing to me. Some things I wouldn't wish upon my worst enemy. Being on the anti-psychotic leads to depression, anxiety, suicidal thoughts, akathisia, hating every aspect of life, and weight gain and coming off completely means thinking I have 38 girlfriends and can stop missiles in their tracks. Could a mood-stabilizer be the appropriate balance to end this nightmare? Can someone have Bipolar Mania so severe they develop Psychosis but not actually be Schizoaffective?
I've come across a few academic papers that seem to give hope to people with treatment refractory OCD. These papers suggest that not all OCD may be serotonin-related, and may be related more to high levels of the neurotransmitter glutamate. In which case a number of drugs could show potential benefit. Has anyone here given any a try?