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I've been relatively stable with a few jags here and there for almost 2 years, and suddenly I'm experiencing some depression that has me in tears at times, as well as anxiety that results in panic attacks so bad that I feel like I can't breathe. I'm very emotionally labile, reactive to any trigger, sending me to seclusion with my depression. The only thing that has changed is that I swapped Dexedrine to Bontril-PDM for my weight management (and with Bontril-PDM, off-label ADHD management, idiopathic hypersomnia management, and treatment of refractory bipolar depression). I'm thinking this may be the trigger, but I needed to take a break from Dexedrine because my receptors were too desensitized to it and I was starting to gain weight, sleep all day, become very inattentive (like almost having wrecks kind of inattentive), and feel a little depressed. So I may have identified my trigger, but I need to take a good break from Dexedrine so when I resume it, it will work as it did when I first started it. My question is how does one prevent depression (neurochemical, not cognitive)? Is there something that can be temporarily added to my cocktail? I see my pdoc Friday. I have tried lithium and it causes seizures. Depakote makes me a zombie. Lamictal causes horrendous acne. I'd rather not add a second antipsychotic. Increasing the antidepressants seem to do nothing. Should I just get back on Dexedrine ASAP? Or continue to give it a break and try other alternatives? I thought about trying Ritalin again, but a much higher dose than I've tried before, like 40-60 mg in Metadate CD form (the only form I felt anything from with methylphenidate). Concerta and regular Ritalin are useless, and I've heard bad things about Ritalin LA. Any responses or insight would be much appreciated! Thanks in advance!
I feel like I should know this. So I have been having some mild swings, after a mixed depression in December. It's a fairly regular cycle of sluggishness and fog, then hypomania. Some agitation thrown in for fun. So I called my pdoc and he told me to use the PRN Klonopin well, as needed. Heh. Double up if it's bad. So I have been really trying to be more liberal with it, if I keep doing this when I get hypomanic will it prevent the resulting depressive swing?