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Found 21 results

  1. Hello People So I'm in the process of tapering off mirtazapine (Remeron) and seem to be having some pretty shitty withdrawal effects. Some are physical (teeth grinding, fatigue), but some are returning/worsening mental health symptoms (shitty mood and emotion regulation, increased depression, anxiety, indecisiveness, and obsession). The goal in tapering off this med is to eliminate it's "hangover effect," so I'm hoping this is just some extended rebound effect/temporary withdrawal symptoms. I can't seem to get out of bed in morning and make it to work on time to save my fucking life in any case, so it would be nice if I could eliminate one factor in that. It's been 2 1/2 weeks since I went down 3.75 measly milligrams, but I don't know if I can take much more of this. Any experience with this? Suggestions? Oh, and when I called my psychiatrist, a nurse called me back and said withdrawal effects should only be physical...bullshit, right?
  2. Hey everyone. I’ve been in a bad way for 4 1/2 years when remeron stopped working for sleep and sudden onset OCD (ruminating thinking, intrusive thoughts, looping songs), treatment resistant insomnia, anxiety- stick in fight flight, panic, 24/7 derealization, brain fog and dizziness set in. Over time with symptoms not going away, depression set in. Obviously my meds were not working. I am on day 11 off Zoloft/remeron after a long taper. I and am wondering when these meds will completely be out of my system. Am I out of the woods yet? Or could withdrawal still jet hard? I’m hoping these meds are part of my problem and some of this hell I’ve been going through will get better. I have felt bad since discontinuation, but I always feel awful, so not sure what’s what. How long does withdrawal typically last? I’m still on 5 mg lorazepam a day (I know that’s a lot and plan to start weaning when I’m ready) 20 mg geodon X2 and 2 mg prazosin. Wondering if my meds could be doing this to me? Ive been on Zoloft for over 14 years, remeron for 8 1/2 years, lorazepam for 8 1/2 years and geodon for 11 1/2 years. As mentioned, I have been wanting to get off Zoloft/remeron (really all my meds) and have been weaning for months off these two, but have been scared to pull the plug. After reading about MAOI’s, which I have never taken and talking to the doctor, I decided to stop to give me the opportunity to try Nardil, but I’m wondering if less is more may be the ticket for me and maybe I should hold off on trying Nardil. I just don’t know.
  3. I realize that I have been having a bad physical reaction to remeron since I started taking it near the end of November. I am currently taking 7.5 mg, cutting down from 15 mg two weeks ago. I was wondering if anyone had stopped taking remeron after being on a 7.5 mg dose or do you need to break that in half? I was also wondering if anyone had gone from remeron to seroquel? I am already having a hard time sleeping and was thinking about going back to my old 50 mg seroquel dose at night instead of the remeron. I will see nurse practitioner on Monday but wanted to hear experiences from other people.
  4. Hello everyone, my name is Nicholas and I'm a 21 years old guy from Italy. I suffered from chronic insomnia from the age of 15 and in mid-February 2017 was prescribed before bedtime the antidepressant mirtazapine at 15 mg and the antipsychotic olanzapine at 2,5 mg. I took them for 2 weeks without improvement. Therefore the psychiatrist increased mirtazapine at 30 mg and olanzapine at 10 mg. Now I believe that he thought I had bipolar disorder type 1 but I hadn’t any mental illnes. I took olanzapine at 10 mg because I think was only a tranquilizer and because I trusted the doctor. Olanzapine made me sleep for 13 hours but I was no longer myself. After 5 days I tried to split the tablet but it gave me a strange effect. So I continued for others 15 days at 10 mg because I really needed to sleep. Then in April 2017 I tapered olanzapine in 1 week because I could not live anymore like that. I took it for a total of 48 days. After this I reduced mirtazapine to 15 mg and 1 week later I stop cold turkey. At that time I took the benzodiazepine brotizolam at 0,25 mg for 2 weeks to help me sleep. The withdrawal symptoms were terrible for 4 months and I have not been the same anymore. When I was on mirtazapine and olanzapine I had eyelids fasciculation 2 or 3 times per day. When I quitted olanzapine the eyelids fasciculation ceased. 2 weeks after withdrawal from olanzapine and 1 week from mirtazapine I started to have frequently intermittent muscle twitching in the left thigh and occasionaly pulsating muscles in other parts of the body. After less than a couple of months they have decreased in frequency and intensity but didn’t stop completely. During this period I was forced to take the antidepressant sertraline and the benzodiazepine diazepam because for the new psychiatrist I had obsessive compulsive disorder with an obsession for the damage of antipsychotics. I did not have anything like that and could taper and withdraw after 3 months in July 2017. Now I think maybe that the muscles twitching have diminished because diazepam is also a muscle relaxant. In August 2017 I started to have continuous fasciculations in the legs when I lie down and less frequently when I sit while I never had them when I move. Few times a day I had pulsating muscles also in the arms and the trunc but never in the face. I never had muscle twitches in multiple parts of the body at the same time. In September the muscles twitching moved for 1 week in the lower abdominals. In October 2017 for 2 weeks the muscles twitches suddenly stopped in the legs and continued in the rest of the body about 10 times per day. When the muscles twitching returned they were milder. Sometimes the fasciculations are so mild that when I looked at my calf I saw them without feel them. In the legs they have become more single rapid muscular contractions than pulsating muscles. Soon after I started to have continuos pulsating muscle in my upper lip. The muscle twitch was very mild and lasted 2 weeks but after it I have sometimes pulsating muscle also in my face. Do you think it is a tardive dyskinesia caused by olanzapine despite I haven’t involuntary body movements? Do you think it could be some other side effect caused by olanzapine or maybe mirtazapine? It’s 8 months that I’ve it. I have been visited by several psychiatrists and neurologists and everyone said it was just stress. Even if I do not have the symptoms of tardive dyskinesia I do not know what else it could be: I’m not stressed and I do not suffer from anxiety, I do not take stimulants, I can sleep, I have had blood tests and I haven’t electrolyte imbalances or hypoglycemia, I did electromyography and had normal results. The thing that worries me most is that there is a very large amount of medical literature that associates tardive dyskinesia with cognitive impairments. If it were to be tardive dyskinesia do you think that the fact that for almost 2 weeks the muscles twitches had almost disappeared means that I am healing? Thank you and greetings from Italy.
  5. Hi, I have been on Remeron for about three years for anxiety, OCD, and depression. I started at 60mg, but that was pretty stimulating after dosing it all at night. Now, I take 22.5mg before sleep. Depending on my legs/hips tension levels, I always get restless legs about 45-60 minutes after my dose, and it keeps me from sleeping right away. I've had this since I started the med, and now that I do yoga/stretching, it's even been worse. Some nights it is very severe. Would lowering to 15mg help? Or anything else? I wonder if it's a histamine or noradrenaline thing. Thanks.
  6. I'm having a hell of a hard time and experiencing rather weird symptoms. Whether they've anything to do with Mirtazapine (Remeron) is something that I strongly feel but can't quite convince any doctor of. I was put on 15 mg of it in spring 2015 for depression and a severe insomnia - I hadn't slept an hour like since 25 nights back then! The benefits showed immediately within a day and surprised myself and my family. I would sleep well and be in a very happy and cheerful mood. Then however, from summer 2016 I developed some strange food intolerances; caffeine, sugar, fruits containing high amounts of fructose, yoghurt, butter and so on. Eating anything of that would cause me jitteriness and insomnia. I steered clear of those foods. From autumn last year though, a lot of those food intolerances have relented and it changed into intolerance towards medicines and supplements that I was on; the thyroid medicine for hypothyroidism, Vitamin D, Calcium, Vitamin E and could never again tolerate any new medicine or supplement. Symptoms resulting from these are, again, jitters, insomnia and a strange kind of feeling of being struck on the head, like I can't hear anything and the thinking becomes very unclear and blurred. Coupled with this is a weird sensation that if a medicine has any potential side-effect (even physical, such as urine retention), I get it at all costs. So I'm steering clear of the culprits here too. However, avoiding the culprits doesn't end my misery, it just helps in avoiding a whole new set of symptoms, because since autumn 2016 I'm under constant brainfog anyway, have heart palpitations immediately after every meal (but worst after breakfast), have concentration and focus issues, lead a life without any hobbies, wishes or desires. Nothing excites me, nothing interests me and nothing catches my attention. Leave tasks pending for months (the most unlike me habbit), have badly lost my sense of humour. My sense of humour was something that I literally used to pride on, and friends from around the world would call me to fresh up if they were having a dull day. My mind feels numb, although it isn´t as if it´s the sedating effect of the Mirtazapine because 90% percent of the nights I don´t sleep well, and on a lot of nights I feel as if I´m asleep with an awake mind! Amidst all this, although initially not effected for the first 17 months, but the libido is not non-existent. If I get them at all, my erections are very tiny and hardly last a minute. The GP who put me on it considered it to be just the effects of anxiety and depression and recommended the doubling of the dose to 30 mg. When I contested that, given that I´ve my doubts of a lot of these issues being brought upon by Mirtazapine itself, she referred me to a psychiatrist. He too strongly denies of Mirtazapine having any hand to play on it and instead thinks it´ll be best to combine it with another antidepressant for day-time. He put me on Paroxetine, boom, a flood of side-effects! Then changed to Fluoxetine (Prozac) - third day on it and having weird feelings. The heart poundings are one and is in fact making me very depressed and hopeless!
  7. For years I've been taking remeron at night for sleep and it helps a lot with my appetite. Last week my doctor switched me from remeron 22.5 mg at night to hydroxyzine 50 mg before bed. He said it would be kind of like getting the antihistamine benefits (sleep, appetite) without the noradrenic and serotonin action of the remeron (remeron tends to make be too activating for me, increasing my anxiety). Does this sound about right? I started the switch 2 nights ago and felt alright until just a few hours ago when I started getting really paranoid and feeling like I was panicking and just out of it. My appetite has been good though, I get real hungry about an hour or so after taking the hydroxyzine just like I did with remeron which for me is a bonus. I'm wondering if my dose at 50 mg is too high though. I'm also taking valium 5 mg twice a day and effexor 37.5 mg once a day.
  8. Would another antihistamine such as Hydroxyzine be something worth trying instead of Remeron for sleep, appetite, and anxiety? I ask this because every time I have been on remeron it has been amazing the first few weeks. I sleep great, wake up refreshed, and eat well and put on much needed weight, which I'm guessing from it's powerful antihistamine effect. But each time after about a month while I continue to sleep and eat better my anxiety actually gets worse, and I get agitated and edgy a lot, which I'm guessing is from the norepinephrine part kicking in? Would a drug like Hydroxyzine or something similar maybe still give me that feeling like I have the first few weeks on remeron without the negative stuff several weeks later? I just with remeron would keep working forever like it always does those first few weeks.
  9. Whenever I've been on remeron, or anything that has strong antihistamine activity, I notice a lot of physical changes. Well the good thing is that it really helps with the physical symptoms of my anxiety, my body which is normally very stiff and tight all over feels more relaxed and loose. But at the same time whenever I stretch real good I get the most agonizing pain in my tendons wherever I stretch. Also my joints hurt a lot in my fingers and toes and I get plantar fasciitis often. Is there any correlation between connective tissue and use of antihistamines or remeron in general?
  10. Whenever I've been on remeron, or anything that has strong antihistamine activity, I notice a lot of physical changes. Well the good thing is that it really helps with the physical symptoms of my anxiety, my body which is normally very stiff and tight all over feels more relaxed and loose. But at the same time whenever I stretch real good I get the most agonizing pain in my tendons wherever I stretch. Also my joints hurt a lot in my fingers and toes and I get plantar fasciitis often. Is there any correlation between connective tissue and use of antihistamines or remeron in general?
  11. This is my second post. So again, bear with me. I have some issues with substance abuse, depression, and just about every type of anxiety disorder you can find in the DSMs. With my "addictive personality," Adderall has become a drug that I just can't get enough of. I've been taking it for over a year and have come to a conclusion that if I keep taking it, things will only get worse than they are now. I don't have a job and live with my parents. I'm a part-time student and only take a couple courses per semester. It's been years since I held an official job. At first, I thought that Adderall was enhancing my performance--in everything, but that couldn't be further from the truth. The most I've gotten out of it are As in my classes and repetitive artwork that seems to be getting "bland" over time. After a ton of obsessive research, I concluded that mirtazapine might be the key to curing my anxiety and depression, help me gain weight, and quit Adderall. I don't want to get into pharmacology of the combination of Adderall and mirtazapine, because I'm way, way too tired. Anyway, my doctor agreed with me that mirtazapine may be a fantastic option to cure all of what I've stated above. I was prescribed 15 milligrams to take nightly. The first night I was out cold, and the next day wasn't too bad at all. The second day (today) however, I'm cranky, impatient, exhausted, and guilty for not doing anything with my life. I know I want to give this medication a fair shot, but I'm one of those people that read up way too much on other's experiences with medication. The positives so far are that I'm not craving Adderall as much as I usually do, and clonazepam (which I forgot to note) isn't really needed either. Still, with this lethargy there is absolutely no way I could hold a job or even continue in school. All in all, I want to know if anyone can relate, especially if they have been on Adderall and mirtazapine simultaneously. Also, has anyone quit Adderall cold-turkey from a 40mg dose (or over)? If so, how long did it take to get your mental and physical energy back. I have the rest of summer to solve this, but as all people that take pharmacueticals know, seeing a doctor/psychiatrist every two weeks and continued trial-and-error fails takes so much time, money and stress. Thanks.
  12. I was on Prozac, Remeron (15 mg), and Seroquel (200-250 mg) for a while but my depression (particularly anhedonia) is still really severe. I'm having trouble functioning. I've been on Seroquel for a long time and it's really helped me. At one point, it was all I was on. We added Remeron 15 mg, and at some point I'll probably have to go up because it's not quite working enough. The Remeron and Seroquel helped me sleep very well and I felt stable and calm on that combination. But I had no motivation and severe anhedonia so the dr added Wellbutrin. I've been on it twice before, once when I was younger, and the second time a year ago and it was great the first time but the second time I had really severe anxiety with mild paranoia and agitation. We thought the other meds would cancel that effect out of the Wellbutrin, but I am so agitated. I unintentionally gripped my bf so hard today when I was trying to calm myself down that I broke his skin. My dr. wants me to try until Wednesday. I started last Saturday. At what point should I stop? What level of agitation or anxiety is just too much? Do these meds cancel each other out? I've been mood disorder NOS in the past but this dr doesn't think I have that. He's still working at finding out a diagnosis, so unfortunately I can't help too much with that. It's depression and anxiety to really simplify it, with a lot of other symptoms.
  13. Hey guys I'm relatively new here. I've been on many different medications and med combinations in the past. So just curious if any of you have ever been on a cocktail similar to mine. So far it has worked wonders. I've been on this combination for months. The weight gain from the remeron was hard to deal with, but eating better and exercise helped that, and the munchies I got from it became less and less over time. I'm on Propranolol instant release 80mg 3 times a day (I used to take this 3 times a day, but now have weaned myself down to once a day when needed. The whole idea of taking a 'heart medication' still sketches me out. But apparently propranolol has a low side effect profile, I think? Lol) Gabepentin 300mg 3 times a day (however my doc for some reason gives me a monthly script of 270 300mg pills) Remeron 30mg at night Effexor ER 150mg in the Am ( apparently the combo of effexor and remeron is called 'California rocket fuel') A little bit about me. I have depression and generalized anxiety, and currently being tested for possible bipolar disorder. I have had severe substance abuse issues in the past so I have to go the non narcotic route.
  14. I've been taking Adderall IR for a little while now (few months) taking 30mg at 8am and another 15mg at noon, and recently just added Remeron 15mg every night for sleep. I've been noticing a major fluctuation in my moods about 1-2 hours after taking the Remeron. So in addition to the somewhat slumped feeling I had already from the daytime meds wearing off, once the night med kicks in I am just like totally depressed and out of it. Has anyone else tried this combination and what effects did you see occur?
  15. Hi! I'm bipolar 2 and taking lamictal which balanced my mood swings but has made me just depressed. I am now taking remeron at night for sleep and depression and it has helps slightly with sedation (I have been taking 7.5 mg) i want to know if the hunger comes later because it really hasn't madero hungry which is good cause I am terrified of weight gain and would have to stop immediately. But I was wondering if I could still gain weight from it even if I don't eat a lot or eat badly? Also, how long does it take to take effect for depression. Thanks. Also, I'm starting adder all soon for my ADHD. Will that help with any weight gain? Thanks
  16. Hi! I'm bipolar 2 and taking lamictal which balanced my mood swings but has made me just depressed. I am now taking remeron at night for sleep and depression and it has helps slightly with sedation (I have been taking 7.5 mg) i want to know if the hunger comes later because it really hasn't madero hungry which is good cause I am terrified of weight gain and would have to stop immediately. But I was wondering if I could still gain weight from it even if I don't eat a lot or eat badly? Also, how long does it take to take effect for depression. Thanks. Also, I'm starting adder all soon for my ADHD. Will that help with any weight gain? Thanks.
  17. Hello. I started taking Mirtazapine at 15 mg two weeks ago and was tapered off of Zyprexa from 5 mg to 2.5 mg. Starting this Sunday, I have been having strange thoughts about harming others to the point of obsession. I've had OCD in the past, but I've never had these type of thoughts before. I've gotten totally off of Zyprexa before so I don't believe it was due to Zyprexa withdrawal. Could it be due to the Remeron?
  18. This is my second post since joining. I am looking to find out any info about what my combination of meds is doing inside my brain. Look at my introduction post if you want to know about my condition. I am now prescribed venlafaxine 150mg in the morning, mirtazapine 30mg and quetiapine fumarate 150mg at night, with clonazapam 2mg PRN. I know how the venlafaxine and mirtazapine theoretically work together to boost 5ht and NE "California Rocket Fuel". I know that since i'm only at 150mg Venlafaxine it is only acting as a SSRI, but i think i probably will have to increase to 225mg soon, changing it to SNRI. My question is what is the quetiapine fumarate 150mg going to do? What are its affects going to be upon 5HT NE DA systems as an adjunct to the "California Rocket Fuel"
  19. I am on 30mg now, and supposed to go up to 45. Pdoc says I will probably need a high dose to combat the OCD anxiety. He says he usually doesn't like to go above 60 mg with this med, but has a few patients on as much as 90 mg. Anyone taken this med at high doses? Was it successful? Seems like a lot of people are on this as an add-on, or for sleep/appetite at lower doses.
  20. Hi guys and gals, As you can see from my signature, I've been taking 30mg Remeron (mirtazapine, Zispin) for about 5 years. My doctor has me trialing Seroquel at the moment, which is KNOWN to sometimes lead to diabetes. But does Remeron? Has anyone developed prediabetes or full blown diabetes while taking Remeron? Since my pdoc Rx'd Seroquel for me, I thought it would be a good idea to invest in a home glucose meter. I've only taken 4 doses of the Seroquel. I tested my blood glucose and lo and behold I'm getting numbers that suggest prediabetes (105 mg/dl after 8 hour fast, 195 mg/dl 1 hour after eating, and 136 mg/dl 2 hours after meal)---all suggestive of prediabetes and damn close to full blown diabetes. Talked to the doc about it, and he wants me to stop the Seroquel temporarily, and retest blood glucose after 3 days. If still high, then he wants to order lab testing. I tend to doubt that my glucose levels were raised from 4 doses of Seroquel, so I'm leaning more toward it being possibly caused from the Remeron. My last point of reference was 2 years ago when my glucose levels were normal (after 3 years on Remeron). Any comments? This is scaring the crap out of me-----
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