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Found 2 results

  1. Hello CrazyBoards, I started 5mg Trintellix a week ago and in a nutshell, felt 40-50% better the very next day. Before I get deafened with shouts of "PLACEBO!", think again since I'm treatment-resistant (20+ years) and never expect meds to work - because they nearly always don't. FTR I've tried tens of med combos, treatments, ECT, dTMS unsuccessfully. They either make me worse, have no effect or help somewhat and then poop-out within 2-4 weeks. Furthermore my mood started dipping significantly 3 days ago so I upped the dose to 7.5mg last night, again not expecting anything and lo and behold, I felt significantly better - like "naturally" or "simply" better today. Has anyone heard of, or experienced such a rapid improvement? Pete
  2. Heyup, I'm taking Vyvanse for my 20+ year treatment-resistant depression and it's working better than anything I've ever tried (the bad news is that the last 3-4 days it's losing its potency and/or taking longer to kick in, but that's another story). I am asking about its variable effectiveness since I also found it to vary even when it was still potent. E.g. Monday my mood would be 6/10 depression (10/10 is best mood) then Tues 4/10 then Weds 7/10. Anyone know why this variability happens? Anyone got any tips? FTR I'm on 150mg Brand Lamictal, Abilify 5mg, 15mg Percocet (for chronic pain), 60mg Vyvanse, 36mg concerta (since the Vyvanse lasts 8 hours max), 20mg Omeprazole (for NERD, GERD's geeky cousin), 100mg trazodone (for sleep), 300 ranitidine (for NERD). I take the meds at the same times every day. Many thanks! Pete
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