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Just got a phone call from my pharmacist. She will not fill the Seroquel and Abilify together due to the black box warning about prolonged QT interval causing sudden death. Any of these class of medications, she is urging that I have an EEG to see how my heart is doing before starting any of them. I am 67. I need to be able to sleep and insomnia is a big player in my life. Seroquel helps me sleep, but pharmacist does not want me to mix Seroquel with anything else in any category. So, will stop the Seroquel tonight, only have been on this for 3 days, so I shouldn't have any adverse effects. I do have GAD and panic disorder with insomnia. She did fill Abilify for me, but that is activating (prior experience). I need something to counterbalance the anxiety it provokes and the insomnia. I asked her to check Pamelor, a trycyclic antidepressant and it is not recommended for anyone over 65, only due to sedation issues. I was on Pamelor for 30 years about 10 years ago and went off of it due to having interactions with other medications. I tried to go back on it this year while on Zonegran but it interacted with that medication. I am now off of Zonegran due to a kidney stone. I do feel that Pamelor is the best for my GAD and does aid with sleep. Now that I am a senior trying to take medication I am finding all these obstacles. Reaching out to this community to see if anyone has any suggestions or had experience combining Seroquel an d Abilify. Thanks