newbie73 Posted April 8, 2006 Share Posted April 8, 2006 My PDoc recently prescribed Risperdal for me to help alleviate a problem with "over-elaboration." I also take Adderall XR for add, but .5mg of Risperdal seems to cause my brain to shut down, I'm less organized and my working memory has become nonexistent. Does anyone know what region of the brain Risperidone is meant to target? If it affects the availability of Dopamine in the frontal cortex, then this is likely going to run against the intended effects of Adderall... Link to comment Share on other sites More sharing options...
dan Posted April 8, 2006 Share Posted April 8, 2006 Well it's comlicated and I'm really not the best person to answer this but I'll try. The short anwer is the whole brain, but: there are diffferent flavours of dopamine which get used in diffferent ways. I think there's 5 types of dopamine: D1, D2, D3, D4 and D5. The theory last time I checked was that AAP's block dopamine D...umm...I think it was 3,4 and 5 receptors which straightens out the limbic region and positive psychotic symptoms and almostt leaves D1 and D2 receptors in the prefrontal cortex. An anti depressent then inhibiits the reuptake of dopamine in the prefrontal cortex and targets mostly d1 and d2 receptors (I'm really not sure about those numbers though). Maybe repost this thread over in Phamacologgy geeks, someone there will know. Dan Link to comment Share on other sites More sharing options...
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