does cymbalta cause weight gain

[blackbunny19]

i'm suppose to be starting cymbalta soon. But im worried about weight gain side effects. Has anyone gained weight from this drug?

thanks

[revlow]

My think it's supposed to be weight neutral, but I'm not sure. Maybe someone else has the hard facts?

I was on it several months, maybe 5 or 6? (Didn't do anything for my depression.) I actually lost weight while I was on it, but I'm sure that was due to the fact I was: 1) recovering from surgery; 2) developed a rare infection; 3) was on a ton of antibiotics; and 4) from all that had severe nausea and lack of appetite.

Bottom line: don't think my weight loss was at all related to cymbalta.

Hopefully, someone will come along who knows more.

PS - You might want to re-post this in the Non-SSRI Antidepressants forum. Cymbalta is a Non-SSRI antidepressant.

[revlow]

blackbunny19:

I did a search of the PI for Cymbalta. The PI is downloadable here: http://cymbalta.com/index.jsp - the "Prescribing Information" link is on the bottom left of the page.

This is what the search turned up:

=====================================================

Weight Changes

In MDD placebo-controlled clinical trials, patients treated with Cymbalta for up to 9-weeks experienced a mean weight loss of approximately 0.5 kg, compared with a mean weight gain of 0.2 kg in placebo-treated patients.

In DPN placebo-controlled clinical trials, patients treated with Cymbalta for up to 13-weeks experienced a mean weight loss of approximately 1.1 kg, compared with a mean weight gain of 0.2 kg in placebo-treated patients.

=====================================================

So, it appears that if anything Cymbalta causes some weight loss. (Maybe it actually did contribute to mine, if only slightly?)

[Bianca]

I lost weight on Cymbalta.... switched to Lex and gained some back... going back to Cymbalta.

[Velvet Elvis]

It's been weight neutral for me.

[celestia]

i'm suppose to be starting cymbalta soon. But im worried about weight gain side effects. Has anyone gained weight from this drug?

thanks

<{POST_SNAPBACK}>

I have gained weight while on this drug, but it has been from FOOD not cymbalta. I'm a emotional eater. I haven't heard any reports of Cymbalta being a weight gaining drug, in fact the opposite for most.

I can testify to it's efficacy. It raised my from near suicide, (locked up in nuthouse), to just blah. Which is not optimal, but we're still working on it.

The only s/e I had was mild heart racing in the beginning, but it went away after I'd been on it a few weeks. I still take it, 60 mgs. per day. For me, it worked almost overnight. I really needed the norepenephine re-uptake inhibition, apparently.

Go for it! and good luck!

S9