thePunisher Posted April 27, 2006 Share Posted April 27, 2006 I am reading up on my next options in a couple weeks, effexor and cymbalta, I know that higher doses of effexor hit the norepinephrine, but when does cymbalta hit it? Does anyone have an opinion as to which is the better one to try first out of the two I have avoided for a long time? Link to comment Share on other sites More sharing options...
Bianca Posted April 27, 2006 Share Posted April 27, 2006 Cymbalta and Effexor are basically opposite in that way. Cymbalta hits N first and then later the S kicks in. Link to comment Share on other sites More sharing options...
thePunisher Posted April 30, 2006 Author Share Posted April 30, 2006 thx, am I correct that S is the problem with anxiety and the meds that hit the N can make you anxious? I just say that because it seems like strattera and wellbutrin can make you anxious? However I am not sure why the doctor told me they might be my next choices? I have anxiety, ocd - like no compulsions but lots of obsessive thinking and worrying, as well as some add issues that my tdoc says could be alot of my problem. I don't think stims are the way to go because I am anxious - like caffeine bothers me. Cymbalta and Effexor are basically opposite in that way. Link to comment Share on other sites More sharing options...
Guest KManix Posted March 15, 2008 Share Posted March 15, 2008 Like 'thePunisher', my problems are anxiety and obsessive thoughts, OCD without much of the 'C'. After 2 years on Effexor + Lexapro with only minimal improvement, switched to Cymbalta only. No change - until 2 weeks ago when my doctor added a folic acid compound called Deplin. WOW!!! This little trick has kicked the Cymbalta into hi-gear - the improvement was noticable within about 3-4 days, and I feel better than I have in years. Hope this helps someone! I am reading up on my next options in a couple weeks, effexor and cymbalta, I know that higher doses of effexor hit the norepinephrine, but when does cymbalta hit it? Does anyone have an opinion as to which is the better one to try first out of the two I have avoided for a long time? From what I understand Cymbalta hits the N first then the serotin. I was up to 300mg of Effexor per day, and it didn't do much. Switched to Celexa now, not noticing any difference. I was on Paxil before. Meds go round lol. Goodluck with whatever you choose. Are you on any other meds? Tom Link to comment Share on other sites More sharing options...
Zippy Posted March 15, 2008 Share Posted March 15, 2008 In my case Effexor becomes a very different drug at 225 mg. So I think I am getting some norepinepherine at that dose. Link to comment Share on other sites More sharing options...
quiet storm Posted March 16, 2008 Share Posted March 16, 2008 Just wanted to add that cymbalta inhibits serotonin and norepeniphrine at a fairly equal rate. Effexor is pretty much acts like an ssri until you get up to around 200mgs. Cymbalta inhibits both across the enitre dose range Link to comment Share on other sites More sharing options...
Recommended Posts
Archived
This topic is now archived and is closed to further replies.