lemonflavor Posted June 12, 2006 Share Posted June 12, 2006 Does this mean Zyprexa reduces serotonin? I wonder how Zyprexa helps with depression if this is the case. Also, if it is used with an SSRI (I realize this is what Symbyax is) wouldn't they cancel each other out? Also, does this basically reduce adrenaline? "Zyprexa (olanzapine) is a selective antagonist (i.e. it gets in the way of) for key serotonin (5HT2A/2C Ki=4 and 11 nM), muscarinic (M1-5 Ki=1.9-25 nM), and dopamine (D1-4 Ki=11-31 nM), receptors. It also blocks the action of histamine (H1 Ki=7 nM), and adrenergic (a1 Ki=19 nM) receptors. It also binds weakly (in that you may or may work this way for you) to GABAA, BZD, and b adrenergic receptors (Ki >10 �M)" Link to comment Share on other sites More sharing options...
lemonflavor Posted June 15, 2006 Author Share Posted June 15, 2006 Calling all geeks... Link to comment Share on other sites More sharing options...
Recommended Posts
Archived
This topic is now archived and is closed to further replies.