Velvet Elvis Posted December 9, 2006 Share Posted December 9, 2006 According to a new study posted at pubmed New Study Posted at PubMed BACKGROUND: This multicenter, randomized, fixed-dose, double-blind, placebo-controlled study evaluated efficacy of extended-release dexmethylphenidate (d-MPH-ER) in adults with attention-deficit/hyperactivity disorder (ADHD). METHODS: Randomized adults with ADHD (n = 221) received once-daily d-MPH-ER 20 mg, 30 mg, or 40 mg or placebo for 5 weeks. The primary efficacy variable was change from baseline to final visit in DSM-IV ADHD Rating Scale (ADHD-RS) total score. Secondary efficacy parameters included the proportion of patients with improvement >/=30% in ADHD-RS total score and final scores on Clinical Global Impressions-Improvement (CGI-I) scale. RESULTS: Of 218 evaluable patients, 184 completed the study. All d-MPH-ER doses were significantly superior to placebo in improving ADHD-RS total scores. Placebo scores improved by 7.9; d-MPH-ER, 20 mg, improved by 13.7 (p = .006); d-MPH-ER, 30 mg, improved by 13.4 (p = .012); and d-MPH-ER, 40 mg, improved by 16.9 (p PMID: 17137560 [PubMed - as supplied by publisher] http://www.ncbi.nlm.nih.gov/entrez/query.f...t_uids=17137560 Link to comment Share on other sites More sharing options...
Loon-A-TiK Posted December 10, 2006 Share Posted December 10, 2006 stupid question that i should probably know the answer to- is focalin a stim? i'm looking for a non-stim solution to my ADD problem. Link to comment Share on other sites More sharing options...
Maddy Posted December 10, 2006 Share Posted December 10, 2006 yes it is a CNS stimulant. for more info you can go here: http://www.rxlist.com/cgi/generic4/focalinxr_cp.htm Link to comment Share on other sites More sharing options...
Loon-A-TiK Posted December 10, 2006 Share Posted December 10, 2006 drats! it seems like strattera is the only non-stim option, and it didn't do anything. guess it is adderall for me at least for now Link to comment Share on other sites More sharing options...
Velvet Elvis Posted December 11, 2006 Author Share Posted December 11, 2006 It's based on ritalin. It's the right hand isomer of methyphenidate. As such it's more active of NA than DA and thus might not have as many problems when taken in conjunction with an AP. Link to comment Share on other sites More sharing options...
Maceo Posted June 17, 2007 Share Posted June 17, 2007 What is Focalin Like compared to Ritalin? Is it more effective with less side-effects or what? Link to comment Share on other sites More sharing options...
Velvet Elvis Posted June 17, 2007 Author Share Posted June 17, 2007 I found it to have much fewer side effects. I could eat on it and stuff. Link to comment Share on other sites More sharing options...
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